Protein Alignment Srpk79D and dsk1

DIOPT Version :10

• Sequence 1: NP_001246881.1
• Gene: Srpk79D / 40461
• FlyBaseID: FBgn0025702
• Length: 1018
• Species: Drosophila melanogaster
• Sequence 2: NP_595327.1
• Gene: dsk1 / 2539847
• PomBaseID: SPBC530.14C
• Length: 544
• Species: Schizosaccharomyces pombe
• Alignment Length: 702
• Identity: 217/702 - (30%)
• Similarity: 292/702 - (41%)
• Gaps: 249/702 - (35%)

  Fly   323 QEDASQYCRGGYHPVVIGDIFDNRFRVV-RKLGWGHFSTVWLCRDLKDEKYVALKVVKSAPHYIE 386
            :|:|..|..||||||.||:.|.:|..|| |||||||||||||..|...::.||||||:||.||.|
pombe    56 EENAEDYHYGGYHPVYIGEEFHHRRYVVERKLGWGHFSTVWLAYDRAAKRRVALKVVRSAEHYRE 120

  Fly   387 TAADEIRLLEAIRDADPMDVKRERIVRLMNHFTVRGVNGMHTCLVFEALGCSLYKLIVKNNYQGL 451
            |:.||||:|:.||:.|...:.::.|:.|:::|..||.||.|.|:|||.||.:|..||....::|:
pombe   121 TSIDEIRILQKIREGDEKHLGKKHIISLLDYFVHRGPNGAHVCMVFEVLGENLLSLIQSYGHRGV 185

  Fly   452 AIAQVRNIIRQVLEGLDYLHSKCSIIHTDIKPENILLVIDNAAAMNQQIDDEINSLRVKGVDFPD 516
            .:..|:.|..|:|..|||||.:|.|||||:||||:|:.||..|..:
pombe   186 PVGIVKQIAYQLLIALDYLHRECGIIHTDLKPENVLICIDQDALQH------------------- 231

  Fly   517 SYISSIEKQTKSRAKWPLIEPNGSTNTNT-NTSNSTATNSNSSTPLAAVIMSTLDKEDTTTTTSS 580
                              ||...:|::.| |||:|...|:...|..|.:|
pombe   232 ------------------IEAPATTSSPTSNTSSSKTRNNTGYTAKAPII--------------- 263

  Fly   581 TLNSNTTSSLASKYSSLLGDSECNGGLGGSANINNRYRTEKKITAKSSGDCDEDAESDTLGEQST 645
                                                         |.....|..|:     |:.|
pombe   264 ---------------------------------------------KRGQSVDNSAQ-----ERKT 278

  Fly   646 LASTMDSPTDLDPEPELDSKPNTVPEPSEGPIPEQPTPNSTNSSCPSHNTATIAKSKINSNILST 710
            .|.          .|..:|||       .|.:
pombe   279 FAK----------NPTKNSKP-------AGQV--------------------------------- 293

  Fly   711 CTSLTSTNEYCFTNTNTTTASTPSAPPSATPSSAPALASATPPSTCTPSFTQIAPSATAPATSTT 775
                                 .||:|.::|.|..|:|..|....:...|
pombe   294 ---------------------IPSSPFTSTLSRFPSLEGAVSEISLRDS---------------- 321

  Fly   776 CTTSAEFYDGDHKTTSTSTTTTSNAISSATTTTATTTTAIAKLNVHANAIPSQNQSQSSQNNTYT 840
                                                    .|.|.|.|:      ..||.:|:.
pombe   322 ----------------------------------------QKHNSHPNS------PFSSGDNSL- 339

  Fly   841 IQSLIDNSN--------VRVKIADLGNACYDYHHFTEDIQTRQYRSIEVLLGAPYNYTADIWSTA 897
               ::|..|        :.||||||||||:...|||.|:|||||||.||:||..:..:||.||.|
pombe   340 ---ILDGVNGSQEPVPKITVKIADLGNACWTRKHFTNDVQTRQYRSPEVILGCRWGASADCWSFA 401

  Fly   898 CLAFELATGDYLFDPHAGESYSRDEDHLAHIVELLGSIPQSVIFRGKHGLKYFTSYGSLRNITKL 962
            |:.|||.||||||||..|.|||:::||:|.|:|||.:.|:.:...|||....|...|.||||.||
pombe   402 CIIFELLTGDYLFDPRNGNSYSKEDDHIAQIIELLVNYPKQMALSGKHSRDLFNRRGELRNIHKL 466

  Fly   963 KPWSLMNVLVEKYDWDPVEAKKFSDFLLPMLEYNPVIRASAAECLQHPWLEQ 1014
            |.|.|.:||.:||.:....|::.||||.|||.::|..|.:|......|||.:
pombe   467 KFWPLKDVLEQKYHFSAELAQQISDFLSPMLCFDPAKRTNAGYMSNSPWLRE 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Srpk79D	NP_001246881.1	Protein Kinases, catalytic domain	336..>504	CDD:473864	83/168 (49%)
		PHA03307	627..>759	CDD:223039	18/131 (14%)
		Protein Kinases, catalytic domain	<844..1012	CDD:473864	86/175 (49%)
dsk1	NP_595327.1	STKc_SRPK	69..516	CDD:271038	208/685 (30%)