DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Srpk79D and srpk3

DIOPT Version :9

Sequence 1:	NP_001246881.1	Gene:	Srpk79D / 40461	FlyBaseID:	FBgn0025702	Length:	1018	Species:	Drosophila melanogaster
Sequence 2:	XP_031753411.1	Gene:	srpk3 / 100125041	XenbaseID:	XB-GENE-1010990	Length:	753	Species:	Xenopus tropicalis

Alignment Length:	821	Identity:	300/821 - (36%)
Similarity:	411/821 - (50%)	Gaps:	167/821 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   254 STPTSIVDEDK--AQQDFLSLSLSPPLNRRRDMPALRGPFVSLSEPRGTLSTTDEIYPDSSDSSL 316
            :||.....:.:  |||...|....||            |...|.||..         |::.:..|
Frog    36 NTPEGYEKDSRPEAQQKVPSAPPPPP------------PPPPLPEPSP---------PEAEEEIL 79

  Fly   317 YVSDEEQEDASQYCRGGYHPVVIGDIFDNRFRVVRKLGWGHFSTVWLCRDLKDEKYVALKVVKSA 381
            ...||||||.:.||:||||||.|||:|:.|:.|:||||||||||||||.|::.:::||:||||||
Frog    80 GSDDEEQEDPADYCKGGYHPVKIGDLFNGRYHVIRKLGWGHFSTVWLCWDMQGKRFVAMKVVKSA 144

  Fly   382 PHYIETAADEIRLLEAIRDADPMDVKRERIVRLMNHFTVRGVNGMHTCLVFEALGCSLYKLIVKN 446
            .||.|||.|||:||..:|::||.|..::.:|:|::.|.:.|:||||.|:|||.||..|.|.|:|:
Frog   145 QHYTETALDEIKLLRCVRESDPRDPNKDMVVQLIDDFKISGMNGMHVCMVFEVLGHHLLKWIIKS 209

  Fly   447 NYQGLAIAQVRNIIRQVLEGLDYLHSKCSIIHTDIKPENILLVIDNAAAMNQQIDDEINSLRVKG 511
            |||||.|..|::||||||:|||||||||.||||||||||||:.:::|..  :::..|....:..|
Frog   210 NYQGLPIRCVKSIIRQVLQGLDYLHSKCKIIHTDIKPENILMCVEDAYV--RRMAAEATEWQKAG 272

  Fly   512 VDFPDSYISSIEKQTKSRAKWPLIEPNGSTNTNTNTSNSTATNSNSSTPLAAVIMSTL------- 569
            ...|.....|...|.|         |.|..:.|............     |.::...|
Frog   273 APPPSGSAVSTAPQQK---------PIGKISKNKKKKLKKKQKRQ-----AELLEKRLQEIEELE 323

  Fly   570 ---DKEDTTTTTSSTLNSNTTSSLASKYSSLLGDSECNGG---------LGGSANINNRYRTEKK 622
               :::....|.|||:              ||.:.:..|.         |..:|:       |:.
Frog   324 REAERKKAEETVSSTI--------------LLNEQDLEGHPEAKMKSVCLEDAAD-------EEP 367

  Fly   623 ITAKSSGDCDEDAESDTLGEQSTLASTMDSPTDLDPEPEL-DSKPNTVPEP------SEGPI--- 677
            :.....||.||  :.||  |:..:....:...|.|.|||| |:....:..|      ..||.
Frog   368 VNEYERGDNDE--KEDT--EKENIEKDDEDEDDDDAEPELVDTDQTWIESPKTNGHLENGPFSVE 428

  Fly   678 PEQPTPNSTNSSCPSHNTATIAKSKINSNILSTCTSLTSTNEYCFTNTNTTTASTPSAPPSATPS 742
            |:.......:..|.:.....:.:|.:.|:       .|.::.|...|.........::....:..
Frog   429 PQLEDEEDEDDDCLNPEEFNLDESNVESD-------YTYSSSYEQFNGELPNGQHKNSELQFSEF 486

  Fly   743 SAPALASATPPSTCTPSFTQIAPSATAPATSTTCTTSAEFYDGDHKTTSTSTTTTSNAISSATTT 807
            ||.....|...:.|     .:|.|..:..|           |.|.   |:|....|..:|:::|.
Frog   487 SASVFPEALESAAC-----GLAISEDSALT-----------DRDE---SSSCHDRSRTVSASSTG 532

  Fly   808 TATTTTAIAKLNVHANAIPSQNQSQSSQNNTYTIQSLIDNSNVRVKIADLGNACYDYHHFTEDIQ 872
            ....|:.:...::..|.:..:|..:                 :|||||||||||:.:.|||||||
Frog   533 DLPKTSKMRAADLLVNPLDPRNADK-----------------IRVKIADLGNACWVHKHFTEDIQ 580

  Fly   873 TRQYRSIEVLLGAPYNYTADIWSTACLAFELATGDYLFDPHAGESYSRDEDHLAHIVELLGSIPQ 937
            ||||||||||:||.|:..||||||||:|||||||||||:||:||.|||||||:|||:||||:||:
Frog   581 TRQYRSIEVLIGAGYSTPADIWSTACMAFELATGDYLFEPHSGEDYSRDEDHIAHIIELLGNIPR 645

  Fly   938 SVIFRGKHGLK-------------------------------YFTSYGSLRNITKLKPWSLMNVL 971
            .....||:..:                               :||..|.||:|||||||||.:||
Frog   646 HFALSGKYSREFFNRRDHIALITELLGKIPRKFAMLGKYSKDFFTKKGELRHITKLKPWSLFDVL 710

  Fly   972 VEKYDWDPVEAKKFSDFLLPMLEYNPVIRASAAECLQHPWL 1012
            ||||.|...:|.:|:|||.||||..|..||||.|||:||||
Frog   711 VEKYGWPQEDAAQFTDFLTPMLEMVPEKRASAGECLRHPWL 751

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Srpk79D	NP_001246881.1	STKc_SRPK	336..>504	CDD:271038	98/167 (59%)
		S_TKc	347..>492	CDD:214567	90/144 (63%)
		STKc_SRPK	<844..1012	CDD:271038	112/198 (57%)
srpk3	XP_031753411.1	PKc_like	97..>285	CDD:419665	104/189 (55%)
srpk3	XP_031753411.1	PKc_like	<542..751	CDD:419665	114/225 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D290680at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm49010
Panther	1	1.100	-	-	O	PTHR24055
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.110