Protein Alignment Srpk79D and srpk3

DIOPT Version :10

• Sequence 1: NP_001246881.1
• Gene: Srpk79D / 40461
• FlyBaseID: FBgn0025702
• Length: 1018
• Species: Drosophila melanogaster
• Sequence 2: NP_001096257.1
• Gene: srpk3 / 100124819
• XenbaseID: XB-GENE-1010990
• Length: 637
• Species: Xenopus tropicalis
• Alignment Length: 748
• Identity: 275/748 - (36%)
• Similarity: 379/748 - (50%)
• Gaps: 158/748 - (21%)

  Fly   271 SLSLSP--PLNRRRDMPALRG----PFVSLSEPRGTLSTTDEIYPDSSDSSLYVSDEEQEDASQY 329
            ||...|  |.:..:|:|...|    |...:..|.|.|.:               .:|||||...|
 Frog    40 SLDSQPGLPEHSLQDVPLSPGPPPTPPTPVLPPPGPLGS---------------DNEEQEDPGDY 89

  Fly   330 CRGGYHPVVIGDIFDNRFRVVRKLGWGHFSTVWLCRDLKDEKYVALKVVKSAPHYIETAADEIRL 394
            |||||:||.|||:|:.|:.||||||||||||||||.||:.:::|||||||||.||.|||.|||:|
 Frog    90 CRGGYYPVKIGDLFNGRYHVVRKLGWGHFSTVWLCWDLQRKRFVALKVVKSAVHYTETALDEIKL 154

  Fly   395 LEAIRDADPMDVKRERIVRLMNHFTVRGVNGMHTCLVFEALGCSLYKLIVKNNYQGLAIAQVRNI 459
            |:.:||:||.|.|||.||:|::.|.:.||||:|.|:|.|.||..|.|.|:|:||:|:.:..|::|
 Frog   155 LKCVRDSDPSDSKREMIVQLIDDFKISGVNGVHICMVLEVLGHQLLKWIIKSNYEGVPLPCVKSI 219

  Fly   460 IRQVLEGLDYLHSKCSIIHTDIKPENILLVIDNAAAMNQQIDDEINSLRVKGVDFPDSYISSIEK 524
            :||||:||||||:||.||||||||||||:.::                        :.||..:..
 Frog   220 LRQVLQGLDYLHTKCKIIHTDIKPENILMCVE------------------------EGYIRRLAA 260

  Fly   525 QTKSRAKWPLIEPNGSTNTNTNTSNSTATNSNSSTPLAAVIMSTLDKEDTTTTTSSTLNSNTTSS 589
            :.....:..:..|:||.     .|::..::.|.:..::......|.::          .......
 Frog   261 EATIWQQSGMPPPSGSA-----VSSAPPSHQNLNGKVSKNKKKKLKRQ----------QKRQQKL 310

  Fly   590 LASKYSSLLGDSECNGGLGGSANINNRYRTEKKITAKSSGDCDEDAESDTLGEQSTLASTMDSPT 654
            |..:...:....|..|| ....||.:.              |:........|:||:..:.:.|
 Frog   311 LEERLRDIHNMEELGGG-DSCPNIQHH--------------CNPGNHEQHWGQQSSQETAVKS-- 358

  Fly   655 DLDPEPELDSKPNTVPEPSEGPIPEQPTPNSTNSSCPSHNTATIAKSKINSNILSTCTSLTSTNE 719
                    :|....:..|......:|   ...:||..|..|..:|:|..::.:..:|      |.
 Frog   359 --------ESTSQLISNPISSTTGDQ---ECADSSLGSGGTTCLAQSPQSTGLYKSC------NG 406

  Fly   720 YCFTNTNTTTASTPSAPPSATPSSAPALASATPPSTCTPSFTQIAPSATAPATSTTCTTSAEFYD 784
            |                .|.|..|:        |.|.|..|:..|.||          ||.....
 Frog   407 Y----------------SSGTRGSS--------PDTHTSGFSSSALSA----------TSGSAIS 437

  Fly   785 GDHKTTSTSTTTTSNAISSATTTTATTTTAIAKLNVHANAIPSQNQSQSSQNNTYTIQSLIDNSN 849
            |...........:.|.:..|.             :...|.:..||..:
 Frog   438 GYSGVRGRGGILSPNLLFCAA-------------DFLVNPLDPQNADK----------------- 472

  Fly   850 VRVKIADLGNACYDYHHFTEDIQTRQYRSIEVLLGAPYNYTADIWSTACLAFELATGDYLFDPHA 914
            ::||||||||||:.:.||||||||||||::|||:||.|...||||||||:|||||||||||:||:
 Frog   473 IQVKIADLGNACWVHKHFTEDIQTRQYRALEVLIGAGYGTPADIWSTACMAFELATGDYLFEPHS 537

  Fly   915 GESYSRDEDHLAHIVELLGSIPQSVIFRGKHGLKYFTSYGSLRNITKLKPWSLMNVLVEKYDWDP 979
            ||.|:|||||:|||:||||.||......|::..:||:..|.||:|..||.|.|.:||||||:|..
 Frog   538 GEDYTRDEDHIAHIIELLGDIPPHFALSGRYSREYFSRRGELRHIQNLKHWGLFDVLVEKYEWSL 602

  Fly   980 VEAKKFSDFLLPMLEYNPVIRASAAECLQHPWL 1012
            .||.:|:|||:||||:.|..||:|::|||||||
 Frog   603 EEATQFTDFLMPMLEFLPEKRATASQCLQHPWL 635

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Srpk79D	NP_001246881.1	Protein Kinases, catalytic domain	336..>504	CDD:473864	99/167 (59%)
		PHA03307	627..>759	CDD:223039	23/131 (18%)
		Protein Kinases, catalytic domain	<844..1012	CDD:473864	103/167 (62%)
srpk3	NP_001096257.1	STKc_SRPK3	96..635	CDD:271120	251/675 (37%)