DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Csp and DNAJC5

DIOPT Version :9

Sequence 1:	NP_001287144.1	Gene:	Csp / 40459	FlyBaseID:	FBgn0004179	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_079495.1	Gene:	DNAJC5 / 80331	HGNCID:	16235	Length:	198	Species:	Homo sapiens

Alignment Length:	239	Identity:	113/239 - (47%)
Similarity:	135/239 - (56%)	Gaps:	46/239 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 KRKLSTSGDSLYEILGLPKTATGDDIKKTYRKLALKYHPDKNPDNVDAADKFKEVNRAHSILSDQ 72
            :|.|||||:|||.:|||.|.||.|||||:||||||||||||||||.:|||||||:|.||:||:|.
Human     6 QRSLSTSGESLYHVLGLDKNATSDDIKKSYRKLALKYHPDKNPDNPEAADKFKEINNAHAILTDA 70

  Fly    73 TKRNIYDNYGSLGLYIAEQFGEENVNAYFVVTSPAVKAVVICCAVITGCCCCCCCCCCCNFCCGK 137
            |||||||.|||||||:||||||||||.|||::|...||:.:.|.::|.|.||||.|||.|.||||
Human    71 TKRNIYDKYGSLGLYVAEQFGEENVNTYFVLSSWWAKALFVFCGLLTCCYCCCCLCCCFNCCCGK 135

  Fly   138 FKPPVNESHDQYSHLNRPDGNREGNDMPTHLGQPPRLEDVDLDDVNLGAGGAPVTSQPREQAGGQ 202
            .||...|..:...:::                 |..||             |.:.|..||...
Human   136 CKPKAPEGEETEFYVS-----------------PEDLE-------------AQLQSDEREATD-- 168

  Fly   203 PVFAMPPPSGAVGVNPFTGAPVAANENTSLNTTEQTTYTPDMVN 246
                          .|....|.:|.|.|.|......:|..|..|
Human   169 --------------TPIVIQPASATETTQLTADSHPSYHTDGFN 198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Csp	NP_001287144.1	DnaJ	17..>86	CDD:223560	54/68 (79%)
Csp	NP_001287144.1	DnaJ	17..79	CDD:278647	48/61 (79%)
DNAJC5	NP_079495.1	DnaJ	15..>84	CDD:223560	54/68 (79%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	106	1.000	Domainoid score	I6610
eggNOG	1	0.900	-	-		E2759_KOG0716
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9631
Inparanoid	1	1.050	217	1.000	Inparanoid score	I3602
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1401920at2759
OrthoFinder	1	1.000	-	-		FOG0001454
OrthoInspector	1	1.000	-	-		otm41299
orthoMCL	1	0.900	-	-		OOG6_105499
Panther	1	1.100	-	-	O	PTHR44027
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3080
SonicParanoid	1	1.000	-	-		X732
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.860