DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Csp and DNAJB14

DIOPT Version :9

Sequence 1:	NP_001287144.1	Gene:	Csp / 40459	FlyBaseID:	FBgn0004179	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_001026893.1	Gene:	DNAJB14 / 79982	HGNCID:	25881	Length:	379	Species:	Homo sapiens

Alignment Length:	104	Identity:	40/104 - (38%)
Similarity:	54/104 - (51%)	Gaps:	25/104 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SAPGMDKRKLSTSGD--------------------SLYEILGLPKTATGDDIKKTYRKLALKYHP 46
            |.|...|...|.||:                    :.||:||:.|.|..:|:||.|||||||:||
Human    73 SKPNCTKDSTSGSGEGGKGYTKDQVDGVLSINKCKNYYEVLGVTKDAGDEDLKKAYRKLALKFHP 137

  Fly    47 DKN--PDNVDAADKFKEVNRAHSILSDQTKRNIYDNYGS 83
            |||  |   .|.|.||::..|:::||:..||..||..|:
Human   138 DKNHAP---GATDAFKKIGNAYAVLSNPEKRKQYDLTGN 173

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Csp	NP_001287144.1	DnaJ	17..>86	CDD:223560	34/69 (49%)
Csp	NP_001287144.1	DnaJ	17..79	CDD:278647	31/63 (49%)
DNAJB14	NP_001026893.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	55..94		6/20 (30%)
		DnaJ	107..>214	CDD:223560	34/70 (49%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	219..241
		DUF1977	271..371	CDD:370429
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910