DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Csp and dnajc3b

DIOPT Version :9

Sequence 1:	NP_001287144.1	Gene:	Csp / 40459	FlyBaseID:	FBgn0004179	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_571705.1	Gene:	dnajc3b / 58154	ZFINID:	ZDB-GENE-000831-4	Length:	502	Species:	Danio rerio

Alignment Length:	83	Identity:	29/83 - (34%)
Similarity:	46/83 - (55%)	Gaps:	8/83 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 GMDKR----KLSTSGDSLYEILGLPKTATGDDIKKTYRKLALKYHPD---KNPDNVDAADKFKEV 62
            |:|:.    |:|...| .|:|||:.::|...:|.|.|||||.::|||   ...|..:|..||.::
Zfish   381 GLDRAHKLLKISRKRD-YYKILGVSRSANKQEIIKAYRKLAQQWHPDNFQSEADKKEAEKKFIDI 444

  Fly    63 NRAHSILSDQTKRNIYDN 80
            ..|..:|:|...|..:|:
Zfish   445 ASAKEVLTDPEMRQKFDS 462

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Csp	NP_001287144.1	DnaJ	17..>86	CDD:223560	24/67 (36%)
Csp	NP_001287144.1	DnaJ	17..79	CDD:278647	23/64 (36%)
dnajc3b	NP_571705.1	TPR_11	41..107	CDD:290150
		TPR repeat	42..70	CDD:276809
		TPR repeat	75..105	CDD:276809
		TPR_11	77..141	CDD:290150
		TPR repeat	110..137	CDD:276809
		TPR repeat	157..184	CDD:276809
		TPR_11	189..254	CDD:290150
		TPR repeat	190..218	CDD:276809
		TPR repeat	223..253	CDD:276809
		TPR repeat	303..337	CDD:276809
		TPR repeat	342..370	CDD:276809
		TPR	348..375	CDD:197478
		DnaJ	394..>500	CDD:223560	25/70 (36%)
		DnaJ	396..461	CDD:278647	24/65 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592382
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930