DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Csp and dnj-14

DIOPT Version :9

Sequence 1:	NP_001287144.1	Gene:	Csp / 40459	FlyBaseID:	FBgn0004179	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_001257015.1	Gene:	dnj-14 / 180746	WormBaseID:	WBGene00001032	Length:	217	Species:	Caenorhabditis elegans

Alignment Length:	218	Identity:	84/218 - (38%)
Similarity:	109/218 - (50%)	Gaps:	41/218 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 APGMDKRKLSTSGDSLYEILGLPKTATGDDIKKTYRKLALKYHPDKNPD-NVDAADKFKEVNRAH 66
            :|..|.......|..||.:||:.|.||.|:|||.||||||:||||||.| :.:..:.|||:|.|:
Worm    24 SPAADHSHDPKKGLHLYNVLGIQKNATDDEIKKAYRKLALRYHPDKNLDGDPEKTEMFKEINYAN 88

  Fly    67 SILSDQTKRNIYDNYGSLGLYIAEQFGEENVNAYFVVTSPAVKAVVICCAVITG---CCCC---C 125
            ::||:..||.:||..|..||.:.|||||:.....::: .|..|.......::||   ||||   |
Worm    89 AVLSNPNKRRVYDEMGETGLKLMEQFGEDEKILQWML-KPWFKWTFFAFGLLTGGFFCCCCGCMC 152

  Fly   126 CCCCCCNFCCGKFKPPVNESHDQYSHLNRPDGNREGNDMPTHLGQPPRLEDVDLDDVNLGAGGAP 190
            ||.|||||||||:||    .||........||                  ||.:|.        |
Worm   153 CCQCCCNFCCGKYKP----KHDDEFADETSDG------------------DVIVDQ--------P 187

  Fly   191 VTSQPREQAGGQP---VFAMPPP 210
            ..|:|......:.   |.|||||
Worm   188 TASEPMPDTNNRQVPIVIAMPPP 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Csp	NP_001287144.1	DnaJ	17..>86	CDD:223560	36/69 (52%)
Csp	NP_001287144.1	DnaJ	17..79	CDD:278647	33/62 (53%)
dnj-14	NP_001257015.1	DnaJ	39..101	CDD:365959	33/61 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159948
Domainoid	1	1.000	79	1.000	Domainoid score	I5632
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	143	1.000	Inparanoid score	I3047
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1401920at2759
OrthoFinder	1	1.000	-	-		FOG0001454
OrthoInspector	1	1.000	-	-		oto18449
orthoMCL	1	0.900	-	-		OOG6_105499
Panther	1	1.100	-	-	LDO	PTHR44027
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3080
SonicParanoid	1	1.000	-	-		X732
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.930