Protein Alignment Ddx1 and Rs1

DIOPT Version :10

• Sequence 1: NP_524212.2
• Gene: Ddx1 / 40457
• FlyBaseID: FBgn0015075
• Length: 727
• Species: Drosophila melanogaster
• Sequence 2: NP_651970.1
• Gene: Rs1 / 44087
• FlyBaseID: FBgn0021995
• Length: 782
• Species: Drosophila melanogaster
• Alignment Length: 564
• Identity: 148/564 - (26%)
• Similarity: 222/564 - (39%)
• Gaps: 148/564 - (26%)

  Fly   171 KKSNNRQFDDYGEAFGKADVIGCLLDLKNQEVSFTKNGQNLG---------VAFRLPDNLAKETF 226
            ||:.....:|.||....||.:    :...|..||.:  .||.         :.:..|..:...|.
  Fly   130 KKAGEEDEEDEGEKMQFADTV----EANEQITSFYQ--MNLSRPLMRAIGVLGYIYPTPIQASTI 188

  Fly   227 YPAVVLKNAEMQFNFGKTDFKYAPGNGFVGACQAGPEHSKANPITGPAAGAPSAKPAPN--APQA 289
             |..:|                  |....|....|...:.|..:  |.......:|..|  ..:.
  Fly   189 -PVALL------------------GRDICGCAATGTGKTAAYML--PTLERLLYRPLNNKAITRV 232

  Fly   290 IIMEPSRELAEQTYNQIEKFKYHLSNPEVRSLLLIGGVRLEEQKAQLMQGTHIVVGTPGRLEEMI 354
            :::.|:|||..|.| |:.|.....:..:|.  |.|||:.::.|:|.|.|...||:.|||||.:.|
  Fly   233 LVLVPTRELGAQVY-QVTKQLCQFTTIDVG--LAIGGLDVKAQEAVLRQNPDIVIATPGRLIDHI 294

  Fly   355 -NSGLVLLTHCRFFVLDEADALLKQGYTELIDRLHKQIPKITSDGRRLQMVVCSATLHAFEVKKM 418
             |:....|......:|||||.:|.:.:.|.:    |:|  |.|..:..|.::.|||: :.:||.:
  Fly   295 KNTPSFTLDSIEVLILDEADRMLDEYFAEQM----KEI--INSCCKTRQTMLFSATM-SEQVKDL 352

  Fly   419 AERLMHFPTWVDLKGEDAVPETVHHVVCLVDPQMDTTWQSLRQP---IGTDGVHDRDNVHPGNHS 480
            |...:..|..|.:.....|.                  .:|||.   |..|...||:
  Fly   353 AAVSLDKPIKVFVNNNQQVA------------------FNLRQEFIRIREDKEGDRE-------- 391

  Fly   481 KETLSQAVKLLKGEYC--VHAIDKHNMDRAIIFCRTKQDCDNLE---RFLRQRGGKHYSCVCLHG 540
                    .:|....|  .|       |..::|.:||:....|.   ..|..|.|:      |||
  Fly   392 --------PILASLICRTFH-------DHCMVFVQTKKQAHRLHILLGLLGVRAGE------LHG 435

  Fly   541 DRKPQERKENLEMFKRQQVKFLICTDVAARGLDITGLPFMINVTLPDDKTNYVHRIGRVGRAERM 605
            :...|:|.|:|:.||.:|:..||.||||||||||.|:..:||..:|....:|:||:||..||.|.
  Fly   436 NLTQQQRLESLKKFKEEQIDVLIATDVAARGLDIVGVKTVINFVMPITTEHYIHRVGRTARAGRA 500

  Fly   606 GLAISLVATVPEKVWYHGEWCKSRGRSCNNT----------------NLTEVRGCCIWYNEP--- 651
            |:::||......|:      .|...::..:|                .||.:        ||
  Fly   501 GISVSLAGEKERKI------VKDIIKNAESTIKNRIIPPEIIEKYRNKLTSL--------EPEIQ 551

  Fly   652 NLLAE--VEDHLNITIQQVDKTMDVPVNDFDGKVVYGQKNLRTG 693
            |:|.|  .|..|..|.||:.||         .:.:.||.|.|.|
  Fly   552 NILDEEQAERQLAKTEQQLSKT---------ERKLLGQTNERRG 586

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ddx1	NP_524212.2	DEAD-like_helicase_N	4..>73	CDD:475120
		SPRY_DDX1	91..242	CDD:293933	16/79 (20%)
		SrmB	283..613	CDD:440279	104/340 (31%)
Rs1	NP_651970.1	SrmB	156..576	CDD:440279	135/522 (26%)