Protein Alignment Ddx1 and eIF4A

DIOPT Version :10

• Sequence 1: NP_524212.2
• Gene: Ddx1 / 40457
• FlyBaseID: FBgn0015075
• Length: 727
• Species: Drosophila melanogaster
• Sequence 2: NP_476595.1
• Gene: eIF4A / 33835
• FlyBaseID: FBgn0001942
• Length: 403
• Species: Drosophila melanogaster
• Alignment Length: 341
• Identity: 95/341 - (27%)
• Similarity: 165/341 - (48%)
• Gaps: 57/341 - (16%)

  Fly   288 QAIIMEPSRELAEQTYNQIEKFKYHLSNPEVRSLLLIGGVRLEEQKAQLMQGTHIVVGTPGRLEE 352
            ||:|:.|:||||.|....:.....::   :|.|...|||..:.|....|..|.|:|||||||:.:
  Fly   100 QALILAPTRELATQIQRVVMALGEYM---KVHSHACIGGTNVREDARILESGCHVVVGTPGRVYD 161

  Fly   353 MINSGLVLLTHCRFFVLDEADALLKQGYTELIDRLHKQIPKITSDGRRLQMVVCSATLHAFEVKK 417
            |||..::...:.:.|||||||.:|.:|:.:.|..:.|.:|.      .:|:::.|||:.. :|.:
  Fly   162 MINRKVLRTQYIKLFVLDEADEMLSRGFKDQIQDVFKMLPP------DVQVILLSATMPP-DVLE 219

  Fly   418 MAERLMHFPTWVDLKGEDAVPETVHHVVCLVDPQMDTTWQSLRQPIGTDGVHDRDNVHPGNHSKE 482
            ::...|..|..:.:|.|:...|.:......|..:   .|
  Fly   220 VSRCFMRDPVSILVKKEELTLEGIKQFYVNVKQE---NW-------------------------- 255

  Fly   483 TLSQAVKLLKGEYCVHAIDKHNMDRAIIFCRTKQDCDNLERFLRQRGGKHYSCVCLHGDRKPQER 547
                  ||  |..| ...|..::.:::|||.|::..|.|   .::....:::...:|||.:.::|
  Fly   256 ------KL--GTLC-DLYDTLSITQSVIFCNTRRKVDQL---TQEMSIHNFTVSAMHGDMEQRDR 308

  Fly   548 KENLEMFKRQQVKFLICTDVAARGLDITGLPFMINVTLPDDKTNYVHRIGRVGRAERMGLAISLV 612
            :..::.|:....:.||.||:.|||:|:..:..:||..||.::.||:|||||.||..|.|:||:.:
  Fly   309 EVIMKQFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPSNRENYIHRIGRGGRFGRKGVAINFI 373

  Fly   613 ATVPEKV------WYH 622
            .....::      :||
  Fly   374 TDDDRRILKDIEQFYH 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ddx1	NP_524212.2	DEAD-like_helicase_N	4..>73	CDD:475120
		SPRY_DDX1	91..242	CDD:293933
		SrmB	283..613	CDD:440279	93/324 (29%)
eIF4A	NP_476595.1	DEAD-like_helicase_N	6..403	CDD:475120	95/341 (28%)