Protein Alignment Ddx1 and tofu-2

DIOPT Version :10

• Sequence 1: NP_524212.2
• Gene: Ddx1 / 40457
• FlyBaseID: FBgn0015075
• Length: 727
• Species: Drosophila melanogaster
• Sequence 2: NP_504786.2
• Gene: tofu-2 / 179089
• WormBaseID: WBGene00017620
• Length: 433
• Species: Caenorhabditis elegans
• Alignment Length: 315
• Identity: 92/315 - (29%)
• Similarity: 139/315 - (44%)
• Gaps: 74/315 - (23%)

  Fly    95 DRGNALAVTPDGLRCQSREFKEWHGCRATTGVRGKGKFYFEATVTDEGLCRVGWSTQQANLDLGT 159
            |:...|.:...||.|:|...|.|.|.|.|.|:.|.||:|:|.|:|.:|||||||:|...:|::|.
 Worm    15 DQDLHLEIDETGLACKSEVKKRWLGARGTAGLYGNGKYYYEVTITSKGLCRVGWATLGGSLNIGK 79

  Fly   160 CRMGFGFGGTGKKSNNRQFDDYGEAFGKADVIGCLLDLKNQEVSFTKNGQNLGVAFRLPDNLAKE 224
            ....||:||||.||.:::|||||..|...|||||.|||.::.:.::|||:....||.: |...|.
 Worm    80 GLDSFGYGGTGMKSTHKKFDDYGLPFTLNDVIGCYLDLDSRTIWWSKNGEQFPAAFSI-DVKYKN 143

  Fly   225 T---FYPAVVLKNAEMQFNFGKTDFKYAPGNGFVGACQAGPEHSKANPITGPAAGAPSAKPAPNA 286
            :   .:|||:.:|:.:..|||...||:.|||.|.....|
 Worm   144 SNTCLFPAVLCQNSSLSVNFGSQPFKFPPGNQFTAVSDA-------------------------- 182

  Fly   287 PQAIIMEPSRELAEQTYNQIEKFKYHLSNPEVRSLLLIGGVRLEEQKAQLMQGTHIVVGTPGRLE 351
                   |:..:...:|.:...|:                              |:||..|..:|
 Worm   183 -------PNENVNWWSYEEQNSFE------------------------------HVVVKLPFAVE 210

  Fly   352 EMINSGLVLLTHCRFFVLDEADALLKQGYTELIDRLHKQIPK-----ITSDGRRL 401
            |.:::...:  |.:..:.:......||.....|.|..:.|.|     :.:||.||
 Worm   211 EDVHNEFRM--HTKLMLTELKRTQCKQDKDGSIRRTLQPISKTICAFLNTDGGRL 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ddx1	NP_524212.2	DEAD-like_helicase_N	4..>73	CDD:475120
		SPRY_DDX1	91..242	CDD:293933	63/149 (42%)
		SrmB	283..613	CDD:440279	20/124 (16%)
tofu-2	NP_504786.2	SPRY_DDX1	11..167	CDD:293933	65/152 (43%)
		COG2865	227..>321	CDD:442112	10/37 (27%)