Protein Alignment Ddx1 and Ddx1

DIOPT Version :10

• Sequence 1: NP_524212.2
• Gene: Ddx1 / 40457
• FlyBaseID: FBgn0015075
• Length: 727
• Species: Drosophila melanogaster
• Sequence 2: XP_318051.5
• Gene: Ddx1 / 1278460
• VectorBaseID: AGAMI1_006387
• Length: 728
• Species: Anopheles gambiae
• Alignment Length: 730
• Identity: 533/730 - (73%)
• Similarity: 620/730 - (84%)
• Gaps: 5/730 - (0%)

  Fly     1 MTAFEEFGVLPELGMATDELDWTLPTDVQAEAIPLILGGGDVLMAAETGSGKTGAFCLPILQIVW 65
            |||||||||:||:..|.||::|.||||||||||||||||||||||||||||||||||||||||||
Mosquito     1 MTAFEEFGVMPEIAKAIDEMEWMLPTDVQAEAIPLILGGGDVLMAAETGSGKTGAFCLPILQIVW 65

  Fly    66 ETLRDLEEGKAGKGGAIGGAVTPWTMSFFDRGNALAVTPDGLRCQSREFKEWHGCRATTGVRGKG 130
            |||||::|||..|..:..|  .|||.|:.|||.|:|:|||||||||||||||||.|.||||||||
Mosquito    66 ETLRDIKEGKTCKTSSHKG--QPWTFSYTDRGQAMAITPDGLRCQSREFKEWHGSRCTTGVRGKG 128

  Fly   131 KFYFEATVTDEGLCRVGWSTQQANLDLGTCRMGFGFGGTGKKSNNRQFDDYGEAFGKADVIGCLL 195
            |:|:||||||||||||||||:.|:|||||.|.|:||||||||||.:|||.|||||||.|||||:|
Mosquito   129 KYYYEATVTDEGLCRVGWSTEMASLDLGTDRFGYGFGGTGKKSNCKQFDAYGEAFGKQDVIGCML 193

  Fly   196 DLKNQEVSFTKNGQNLGVAFRLPDNLAK-ETFYPAVVLKNAEMQFNFGKTDFKYAPGNGFVGACQ 259
            ||..:|::|:|||.:||.||:|.:..|| .:::|||||||||:.||||:|||||....|:...|.
Mosquito   194 DLDGREIAFSKNGTSLGTAFKLSEADAKNNSYFPAVVLKNAEIAFNFGQTDFKYPLPAGYAAVCN 258

  Fly   260 AGPEHSKANPITGPAAGA--PSAKPAPNAPQAIIMEPSRELAEQTYNQIEKFKYHLSNPEVRSLL 322
            ...|:...||.|||:..|  .:|||.|||||||::||||||||||:|||.|||.||.:||||.||
Mosquito   259 VAKENLTENPNTGPSGSAEGEAAKPKPNAPQAIVIEPSRELAEQTFNQIRKFKKHLKDPEVRELL 323

  Fly   323 LIGGVRLEEQKAQLMQGTHIVVGTPGRLEEMINSGLVLLTHCRFFVLDEADALLKQGYTELIDRL 387
            |||||.:.||...|.:|..|:|.||||||::|..|.|||..||||||||||.||||||||:||||
Mosquito   324 LIGGVNVREQIEVLQRGVDIIVATPGRLEDLIGGGYVLLNSCRFFVLDEADGLLKQGYTEMIDRL 388

  Fly   388 HKQIPKITSDGRRLQMVVCSATLHAFEVKKMAERLMHFPTWVDLKGEDAVPETVHHVVCLVDPQM 452
            ||||||||||||||||||||||||:||||||||||||||||||||||||||||||||||:||||.
Mosquito   389 HKQIPKITSDGRRLQMVVCSATLHSFEVKKMAERLMHFPTWVDLKGEDAVPETVHHVVCMVDPQK 453

  Fly   453 DTTWQSLRQPIGTDGVHDRDNVHPGNHSKETLSQAVKLLKGEYCVHAIDKHNMDRAIIFCRTKQD 517
            |.:|||:|..|.|||||.||||.||:::.||||:|||:|||||.:.|||:|||||||||||||.|
Mosquito   454 DISWQSMRTHIQTDGVHARDNVRPGSNTAETLSEAVKMLKGEYTLKAIDEHNMDRAIIFCRTKLD 518

  Fly   518 CDNLERFLRQRGGKHYSCVCLHGDRKPQERKENLEMFKRQQVKFLICTDVAARGLDITGLPFMIN 582
            |||:||:|||.||:.||||||||||.|:|||.|||.||.::|||||||||||||||||||||:||
Mosquito   519 CDNMERYLRQVGGQKYSCVCLHGDRNPKERKANLEKFKNKEVKFLICTDVAARGLDITGLPFIIN 583

  Fly   583 VTLPDDKTNYVHRIGRVGRAERMGLAISLVATVPEKVWYHGEWCKSRGRSCNNTNLTEVRGCCIW 647
            |||||:|:||||||||||||:|||||.||||:|||||||||:||.|||::|.||.||:|:|||:|
Mosquito   584 VTLPDEKSNYVHRIGRVGRADRMGLAFSLVASVPEKVWYHGQWCSSRGKNCWNTELTDVKGCCMW 648

  Fly   648 YNEPNLLAEVEDHLNITIQQVDKTMDVPVNDFDGKVVYGQKNLRTGSGYEDHVEQLVPTVRKLTE 712
            |:|...|||:||||.:||.|::|.|.||:|:||||||||:|.:.||:||:||||||.|.||:|..
Mosquito   649 YDEKMYLAEIEDHLTVTIPQIEKDMKVPLNEFDGKVVYGEKRMNTGTGYKDHVEQLGPVVRELAR 713

  Fly   713 LELQSQSLFLKRLKV 727
            ||.::|:|:||||.|
Mosquito   714 LEREAQTLYLKRLAV 728

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ddx1	NP_524212.2	DEAD-like_helicase_N	4..>73	CDD:475120	59/68 (87%)
		SPRY_DDX1	91..242	CDD:293933	109/151 (72%)
		SrmB	283..613	CDD:440279	260/329 (79%)
Ddx1	XP_318051.5	None