DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rich and AT3G61480

DIOPT Version :9

Sequence 1:	NP_001262205.1	Gene:	Rich / 40456	FlyBaseID:	FBgn0028500	Length:	1429	Species:	Drosophila melanogaster
Sequence 2:	NP_001326817.1	Gene:	AT3G61480 / 825321	AraportID:	AT3G61480	Length:	1123	Species:	Arabidopsis thaliana

Alignment Length:	1363	Identity:	322/1363 - (23%)
Similarity:	520/1363 - (38%)	Gaps:	372/1363 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MYYPVGWPKRVGLALPGESASIRHICCDAVKILVAAVGDDFLGIW-YANPLIPIAYFRRTEDSLR 64
            ||...|||:.:.| |||   |.|.:.......|:..|....|.:| .:...:.:..:.|.:.|||
plant     1 MYMAYGWPQVIPL-LPG---SQRVVYLKLAGRLLLVVSPSHLELWGSSQQRVRLGKYMRDDKSLR 61

  Fly    65 QYGANQLIVWKPDSRQLALLTASGSLLLYQLDFEANGMGILQQIDPPAASLKRDSAELFIKENIP 129
            :.|.|...||.|||:.:|:||:|..|.:|::.|..      :::.|              .|..|
plant    62 EEGENLQAVWSPDSKLIAVLTSSFFLHIYKIKFTD------KRVKP--------------GERQP 106

  Fly   130 RLSLRELCSVTLGSVITTVC-----CISLSE-------LLLATQSCELLRLQWT----------E 172
                .|||..|:..:::...     .:|:|.       :||......|..:.|.          .
plant   107 ----SELCFATISLLLSEQVPFAGKDLSVSNFVRDSKTMLLGLSDGSLYSISWKGEFGGAFSIGS 167

  Fly   173 LEHAENDLEL---------------PALSS-IKLRDIPFYVQQQPQQSARNVPPLNRD------- 214
            ...|.||..|               |.|:| .|....|..||.:....::.:..||.|
plant   168 HPSASNDDRLLSYTLGNGLVSGVASPTLASDDKFSTKPAIVQLELCTRSKLLFVLNSDGQLVVCS 232

  Fly   215 ------SYVASLEYSPFIGG---CAAVFSDRRAAFLIANHLRFETDHMHGFWVPDVEDASVCSVN 270
                  .|..|:.....:||   ||:|.|::
plant   233 VNKKGLKYTESIRAEKKLGGDAVCASVASEQ---------------------------------- 263

  Fly   271 HKFRLLAYGQESSAVKVYAIDDATGGLEFSHRLILTENI-------LPDSLGSVNELKWSPDGCV 328
               ::||.|.....|::|         :.||.:.|...:       ..|..|.||.:.|:||...
plant   264 ---QILAVGTRKGMVELY---------DLSHSISLLRTVSLHDWGYSADYTGPVNNIAWTPDNSA 316

  Fly   329 LAVSWTNGGLSLWSTFGALLMSTLSWDFGL--------NVDLVCQ-NPLK--IRRLEWSTEGYQL 382
            .||.|.:.||::||..|..||||:. ..||        |....|: .||.  ...::|...||:|
plant   317 FAVGWKSRGLAVWSVSGCRLMSTVR-QIGLTSTSSPKINPKQDCKYEPLMSGTSAIQWDEYGYRL 380

  Fly   383 FMLKLHPEKDKSNVLQLQFVKSALSMNPCMTTSPHILLQGDDCLYLNQGNNLELTYAGSHGTFPS 447
            |..:   |.....:|...|.|..|:......|....::.|||.|.:.|..
plant   381 FATE---EASCDRILAFSFGKCCLNRGVSGKTYVRQVMYGDDRLLMVQAE--------------- 427

  Fly   448 SGLGSDEDISGDGDCLELKQSPHTGSILTESKYWTVLQLPLNYAATNWPIRYAAIDPDGLHLAVA 512
                       |.|.|:|..                |:||::|.:.|||:::.|...||.:||||
plant   428 -----------DTDELKLLH----------------LKLPVSYISQNWPVQHVAASEDGKYLAVA 465

  Fly   513 GRTGLAHYSLVTRRWKLFGNESQEKDFVVSGGLLWWHGFVVMGCYSLLDRTDELRCYPADCKLDN 577
            |..||..|.:..::|::||:.|||:. :...||||....||:..:.....|.||..||. ..||.
plant   466 GLHGLILYDVRFKKWRVFGDVSQEQQ-IHCKGLLWLGKIVVICNFIEASETYELLFYPR-YHLDQ 528

  Fly   578 Q--YGHKLQVRAPVISLNSFRHQLIVLTADGIVSLFN------MSKNSAYALDIECAYELDVKSI 634
            .  ...|:.:..|:: ::.::..::|.....|:.:::      ::.:|...|.:....||.:.:.
plant   529 SSLLCRKVLLGKPMV-MDVYQDYILVSYLPFIIHVYHVKIYGELTPSSKADLQLSTVRELSIMTA 592

  Fly   635 CIHPACI----------VSLTVTNLKNELKPQGQLGGDQAETIIVNVCGRILMIQRDAGEQVPNT 689
            ..|||.:          ..|...||.::|..:     :.:..:|:...|.:.::....|.:..
plant   593 KSHPAAMRFVPDQHPREGELDEDNLSSDLSER-----EPSRCLILRGNGELSLLDLVDGRERE-- 650

  Fly   690 LLATCLASCVEVFWLS--HSLERC-AMRDCLWLYSGAHGMRVWLPILPPGRERREGEQGGAQRLH 751
                 |...||:||::  .|.|:. .:.:..||..|..||:||.|.|        |:....|  .
plant   651 -----LTDSVELFWVTCGQSEEKTNLVEEVSWLDYGHRGMQVWYPSL--------GDDPFMQ--E 700

  Fly   752 SFMSKRIMLSFPLKLYPLVVLFDNVIVLGVENESTLYANEQVSHFS-LPFAVMERKSQIYLHKVL 815
            .|:.....|.|..::|||.:|.:..:|:||....:..|:.:...|. .|      ::|..||.:|
plant   701 DFLQLDPELEFDREVYPLGLLPNVGVVVGVSQRMSFSASAEFPCFEPTP------QAQTILHCLL 759

  Fly   816 RQLIKRNLGYSAWEMAQSCCSLPYFPHALELLLHEVLEEEATSKQPIPD-------------AQL 867
            |.|::|:....|..:||.....|:|.|.||.||..|.:.|.:  :|.|:             :.|
plant   760 RHLLQRDKNEEALLLAQLSAEKPHFSHCLEWLLFTVFDAEIS--RPNPNRNQISGPGHLKKLSLL 822

  Fly   868 PSILDFIREFPVYLETIVQCARKTEIALWPYLFSMAGKPKDLFQMCLQSEQLDTAASYLIILQNL 932
            ....|.|:.||.|.:.:|..||||:...|..|||.||....||:.|.|.....|||.|::::..|
plant   823 RKACDLIKNFPEYYDVVVNVARKTDARHWADLFSAAGISTTLFEDCFQRRWYRTAACYILVIAKL 887

  Fly   933 EPSVVSKQYATMLLDIALQQRKWELAKDLIRFLKAIDPNEIDSPRSSMVVNVKIAPPPQVNTQQQ 997
            |...||:..|..||...|.:..::||.:|:|||.....:...:|..|..::.|:.
plant   888 EGVAVSQYCALRLLQATLDESLYDLAGELVRFLLRSGRDIEQAPTESDSLSPKLL---------- 942

  Fly   998 VNQNADAFNMVLGPIARERSFSTTVTSNLPKDKQAS---GTPGVAPVTESSSAGAPSVVRRRSTK 1059
                  .| ::.|...::.|.          ||.:|   .:|.||.|..
plant   943 ------GF-LIFGSSHKKSSL----------DKSSSFKEQSPHVASVKS---------------- 974

  Fly  1060 QRETFCIDLILQRHARQLLQNHKLMDLGYMCAYLDFHLVSWLSQESERAAKLDDFAGALQALHEE 1124
                     ||:.||..|:...:|..|........|.:|.:|.:|....|:|.:||..|:.:.::
plant   975 ---------ILESHASYLMSGKELSKLVAFVKGTQFDIVDFLQRERYGCAQLQNFAAGLELIGQK 1030

  Fly  1125 LDLPIPFPTAAKDDFAQIRGSLRQTGGGGSSQTSESGYFSLATPNGAATQSPQLQPSIREEEEEL 1189
            |.:            ::::..|             ...|.||.           ..|::.:|
plant  1031 LQM------------SELQNRL-------------DAEFLLAQ-----------MCSVKFKE--- 1056

  Fly  1190 QQPSSLPILKT-RSGSQLSFDNFRYR----RLYSLPTSEDDLA-------VDILPQKLSIKLR 1240
                .:.:|.| ...|::.:|.|||.    :.||: |.|..||       :.||..|||...|
plant  1057 ----WIVVLATLLQRSEVLYDIFRYDLRLWKAYSV-TLESHLAFAQYHDLLQILEAKLSATSR 1114

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rich	NP_001262205.1	WD40 repeat	265..312	CDD:293791	8/53 (15%)
Rich	NP_001262205.1	RIC1	713..974	CDD:284476	84/274 (31%)
AT3G61480	NP_001326817.1	WD40	29..489	CDD:225201	132/575 (23%)
		WD40 repeat	67..126	CDD:293791	19/82 (23%)
		WD40 repeat	131..183	CDD:293791	9/51 (18%)
		WD40 repeat	191..243	CDD:293791	11/51 (22%)
		WD40 repeat	306..344	CDD:293791	16/38 (42%)
		WD40 repeat	349..406	CDD:293791	14/59 (24%)
		WD40 repeat	412..442	CDD:293791	12/71 (17%)
		RIC1	673..928	CDD:399802	84/272 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	158	1.000	Domainoid score	I1295
eggNOG	1	0.900	-	-		E1_KOG2006
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H13806
Inparanoid	1	1.050	264	1.000	Inparanoid score	I953
OMA	1	1.010	-	-		QHG55710
OrthoDB	1	1.010	-	-		D261419at2759
OrthoFinder	1	1.000	-	-		FOG0003567
OrthoInspector	1	1.000	-	-		otm2734
orthoMCL	1	0.900	-	-		OOG6_103873
Panther	1	1.100	-	-	LDO	PTHR22746
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3432
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.880