DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rich and R06F6.12

DIOPT Version :9

Sequence 1:	NP_001262205.1	Gene:	Rich / 40456	FlyBaseID:	FBgn0028500	Length:	1429	Species:	Drosophila melanogaster
Sequence 2:	NP_001022277.1	Gene:	R06F6.12 / 174666	WormBaseID:	WBGene00023418	Length:	417	Species:	Caenorhabditis elegans

Alignment Length:	235	Identity:	54/235 - (22%)
Similarity:	88/235 - (37%)	Gaps:	51/235 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   166 LRLQWTELEHAENDLELPALSSIKLRDIPFYVQQQPQQSARNVPPLNRDSYVASLEYSPFIGGCA 230
            ||::  ..:|.|..:|........|......|:...||....|.....|.|.|..
Worm    43 LRVE--SAKHEEEIVEQQQQQPEDLEQGDMIVEDGDQQFMNMVQITQEDMYEAGF---------- 95

  Fly   231 AVFSDRRAAFLIANHLRFETDHMHGFWVPDVEDASVCSVNHKFRLLAYGQESSAVKVYAIDDATG 295
                |..|.|.: |||..|..::            |.:::.:.:.....||.:...|  |:|.:.
Worm    96 ----DVEAGFEL-NHLTEEQLNI------------VVAISQQRQAKQNEQEHNEEVV--IEDGSH 141

  Fly   296 GLEFSHRLILTENILPDSLGSVNELKWSPDGCVL-----AVSWTNGGLSLWSTFGALLMSTLSWD 355
            .....|.:|  ||.. :..|:..|.::..:|.::     .:...:||:::.|......:|. |..
Worm   142 HHMVHHEMI--ENQF-EGDGNGPEEEYDGNGQIIDNAMHIILTNDGGVNITSKQKQFYVSP-SEI 202

  Fly   356 FGLNVDLVCQNPLKIRRLEWSTEG-YQLFMLKLHPEKDKS 394
            ..||:||   |.|       |||. :||..|.|.|.|:|:
Worm   203 ANLNIDL---NNL-------STENVHQLVQLALPPIKEKA 232

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rich	NP_001262205.1	WD40 repeat	265..312	CDD:293791	10/46 (22%)
Rich	NP_001262205.1	RIC1	713..974	CDD:284476
R06F6.12	NP_001022277.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2006
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900