DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment olf413 and Moxd2

DIOPT Version :9

Sequence 1:	NP_001262204.1	Gene:	olf413 / 40453	FlyBaseID:	FBgn0037153	Length:	760	Species:	Drosophila melanogaster
Sequence 2:	NP_647457.2	Gene:	Moxd2 / 194357	MGIID:	2388042	Length:	619	Species:	Mus musculus

Alignment Length:	563	Identity:	165/563 - (29%)
Similarity:	250/563 - (44%)	Gaps:	76/563 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 FNLFLLLLLLA--SGVRAASKLATRSNKTSGSSTASGVGAGTAATSAAAAAASGTPIWDHAIDLN 116
            |.|||||:|.|  .|.|.......|.::....|                          .|:.|.
Mouse     7 FRLFLLLVLAAFSQGKRLGPTSPLRYSRFLDPS--------------------------RAVFLR 45

  Fly   117 DDFRILWQIINQDITFEIQARTLGYVGFGFSPDGNLAGADMAIGWV-DKGQTYFQDRHVTRNGDP 180
            .||....:|    ||||:|.:|.|:||.|.:......|:|:.:|.| ..|..||.|:|:......
Mouse    46 WDFDYEAEI----ITFELQVQTTGWVGLGITDRYTFVGSDLVVGGVLPNGNVYFSDQHLLDEDTL 106

  Fly   181 EPVVDPSQDYMLMLGYENATHTVLRFRRKLDTCDPSHDIAITNDTMRLLYMYHAQDPPHGSVRPG 245
            |.  |.|||..|:...|:|..|.:||.|...|||| ||..||:||||:|..|          .|.
Mouse   107 EQ--DGSQDAELLRLTEDAVSTTMRFSRPFRTCDP-HDRDITSDTMRVLAAY----------GPD 158

  Fly   246 TLPDPARAFRPYRPMVLMQRAQLPMPSPTHDERVRVLELRNEDVELPAGDLPLFWCKMFKLEDIN 310
            .:|..:|.....:.:.|:|..|........|..:..|::.|  ..:|..| ..:.|....|..::
Mouse   159 DIPKMSREHTFVKSIFLLQMLQYDDQDAPEDTIIHDLKISN--FIIPEDD-TTYACTFLPLPIVS 220

  Fly   311 RKHHLIRYEPIY--DSSSSVHYLQHITLHECQGAHAELEEMAREQGRPCLGARSIPLACNAIVAS 373
            :|||:.::|||.  .:.:.||   |:.::.| |..:.|.....|    |.|:......|:.::|.
Mouse   221 KKHHIYKFEPILVERNETMVH---HVLVYAC-GNSSVLPTGIGE----CYGSDPAFSLCSHVIAG 277

  Fly   374 WSRGSEGFTYPHEAGYPIESR-QAKYYLMETHYNNLKPDFAQLHARQMADNSGLKIYFTHVLRPN 437
            |:.|...:.:|.:.|..|.:. ..::..:|.||:|    |..|..  :.|.||:::::|..||..
Mouse   278 WAVGGLSYQFPDDVGISIGTPFDPQWIRLEIHYSN----FQNLPG--IRDTSGMRLFYTSHLRKY 336

  Fly   438 DAGTLSIGMDPNWRHIIPPGQKRVVSEGQC----IEDCTGYAFPQQGINIFAVMMRTHQIGKEVK 498
            |.|.|.:|:.....|.||||.:..:|.|.|    .|:..|  .|...|.|.|.::.||..|:.::
Mouse   337 DMGVLQLGISVFPIHFIPPGAEAFLSYGLCKTDKFEELNG--APVSDIYISACLLHTHLAGRSLQ 399

  Fly   499 LRQIRQTEELPPIAHDSNIDVAYQDFRRLPQSVHSMPGDRLIAECIYDSSSRKAITLGGLTMKEE 563
            ..|.|...:|..:..|.:.|...|:.|.||..|...|||.|:.||.|.:..|..:|.||.:...|
Mouse   400 ALQYRNGTQLQVVCKDFSYDFNLQESRDLPHPVVIKPGDELLIECHYQTLDRDFMTFGGASTINE 464

  Fly   564 SCTVLTLYYPRQKKLTTCHSLPSLPTVLHSLGIEQLATDSNPV 606
            .|.:...|||| ..:::|...|.:..|.:.||.|   ...||:
Mouse   465 MCLIFFFYYPR-INISSCMGYPDIIYVTNELGEE---ASENPM 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
olf413	NP_001262204.1	DOMON_DOH	111..243	CDD:187689	50/132 (38%)
		Cu2_monooxygen	282..407	CDD:279429	31/127 (24%)
		Cu2_monoox_C	438..583	CDD:281675	49/148 (33%)
Moxd2	NP_647457.2	DOMON_DOH	36..172	CDD:187689	54/178 (30%)
		Cu2_monooxygen	194..314	CDD:279429	32/134 (24%)
		Cu2_monoox_C	337..482	CDD:281675	48/147 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846800
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3568
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59784
OrthoDB	1	1.010	-	-		D1472750at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10157
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.860