DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RpLP0 and rla-0

DIOPT Version :9

Sequence 1:	NP_001262202.1	Gene:	RpLP0 / 40451	FlyBaseID:	FBgn0000100	Length:	317	Species:	Drosophila melanogaster
Sequence 2:	NP_492766.1	Gene:	rla-0 / 172943	WormBaseID:	WBGene00004408	Length:	312	Species:	Caenorhabditis elegans

Alignment Length:	318	Identity:	209/318 - (65%)
Similarity:	256/318 - (80%)	Gaps:	7/318 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVRENKAAWKAQYFIKVVELFDEFPKCFIVGADNVGSKQMQNIRTSLRGLAVVLMGKNTMMRKAI 65
            ||||:::.|||.||.|:||||:|:|||.:||.|||||||||.||.::||.|.:|||||||:|||:
Worm     1 MVREDRSTWKANYFTKLVELFEEYPKCLLVGVDNVGSKQMQEIRQAMRGHAEILMGKNTMIRKAL 65

  Fly    66 RGHLENNPQLEKLLPHIKGNVGFVFTKGDLAEVRDKLLESKVRAPARPGAIAPLHVIIPAQNTGL 130
            ||||..||.||||||||..||||||||.||.|:|.||||::..|||:.|||||..|.:|.||||:
Worm    66 RGHLGKNPSLEKLLPHIVENVGFVFTKEDLGEIRSKLLENRKGAPAKAGAIAPCDVKLPPQNTGM 130

  Fly   131 GPEKTSFFQALSIPTKISKGTIEIINDVPILKPGDKVGASEATLLNMLNISPFSYGLIVNQVYDS 195
            |||||||||||.|||||::|||||:|||.::|.||||||||:.|||||.::||||||:|.||||.
Worm   131 GPEKTSFFQALQIPTKIARGTIEILNDVHLIKEGDKVGASESALLNMLGVTPFSYGLVVRQVYDD 195

  Fly   196 GSIFSPEILDIKPEDLRAKFQQGVANLAAVCLSVGYPTIASAPHSIANGFKNLLAIAATTEVEFK 260
            |::::||:||:..|:||.:|..||.|:|:|.|:|.|||:||..||:|||.:|:|.:||.|:|.||
Worm   196 GTLYTPEVLDMTTEELRKRFLSGVRNVASVSLAVNYPTLASVAHSLANGLQNMLGVAAVTDVSFK 260

  Fly   261 EATTIKEYIKDPSKFAAAA-SASAAPAAGGATEKKEEAKKPESESEEEDDDMGFGLFD 317
            ||.|||.:|.||||||||| :|:|||||.....||||.|      ||.||||||||||
Worm   261 EAETIKAFIADPSKFAAAAPAAAAAPAAAAPAAKKEEPK------EESDDDMGFGLFD 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RpLP0	NP_001262202.1	PTZ00135	1..275	CDD:240285	180/273 (66%)
		Ribosomal_P0_L10e	8..182	CDD:240221	122/173 (71%)
		Ribosomal_60s	232..>285	CDD:278836	34/53 (64%)
rla-0	NP_492766.1	PTZ00135	1..312	CDD:240285	207/316 (66%)
		Ribosomal_P0_L10e	9..182	CDD:240221	122/172 (71%)
		Ribosomal_60s	232..311	CDD:278836	52/84 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159074
Domainoid	1	1.000	146	1.000	Domainoid score	I2812
eggNOG	1	0.900	-	-		E1_COG0244
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6517
Inparanoid	1	1.050	423	1.000	Inparanoid score	I987
Isobase	1	0.950	-	0	Normalized mean entropy	S250
OMA	1	1.010	-	-		QHG62173
OrthoDB	1	1.010	-	-		D1102823at2759
OrthoFinder	1	1.000	-	-		FOG0003199
OrthoInspector	1	1.000	-	-		oto18848
orthoMCL	1	0.900	-	-		OOG6_100781
Panther	1	1.100	-	-	LDO	PTHR45699
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2259
SonicParanoid	1	1.000	-	-		X1858
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	17	16.790