DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7130 and DNAJB14

DIOPT Version :9

Sequence 1:	NP_649380.1	Gene:	CG7130 / 40450	FlyBaseID:	FBgn0037151	Length:	128	Species:	Drosophila melanogaster
Sequence 2:	NP_001026893.1	Gene:	DNAJB14 / 79982	HGNCID:	25881	Length:	379	Species:	Homo sapiens

Alignment Length:	147	Identity:	49/147 - (33%)
Similarity:	73/147 - (49%)	Gaps:	27/147 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 KDYYKILGIERNASSEDVKKGYRRMALRYHPDKNDHPQAEEQFREVVAAFEVLFDKEKREIYDQH 67
            |:||::||:.::|..||:||.||::||::|||||..|.|.:.|:::..|:.||.:.|||:.||..
Human   107 KNYYEVLGVTKDAGDEDLKKAYRKLALKFHPDKNHAPGATDAFKKIGNAYAVLSNPEKRKQYDLT 171

  Fly    68 GEEGLKCDDEPAATF-------AQPTPDMLPFMCAVGGTVLFAFAAYKTFQFFN----------- 114
            |.|...|:.:....|       |..||:.| |....||    .|.:.....|.|
Human   172 GNEEQACNHQNNGRFNFHRGCEADITPEDL-FNIFFGG----GFPSGSVHSFSNGRAGYSQQHQH 231

  Fly   115 ----RKKEATHGDGSSS 127
                .::|...|||..|
Human   232 RHSGHEREEERGDGGFS 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7130	NP_649380.1	DnaJ	4..65	CDD:278647	27/60 (45%)
DNAJB14	NP_001026893.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	55..94
		DnaJ	107..>214	CDD:223560	42/111 (38%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	219..241		2/21 (10%)
		DUF1977	271..371	CDD:370429
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810