DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7139 and N4BP2L1

DIOPT Version :9

Sequence 1:	NP_649378.1	Gene:	CG7139 / 40448	FlyBaseID:	FBgn0027532	Length:	969	Species:	Drosophila melanogaster
Sequence 2:	NP_001340556.1	Gene:	N4BP2L1 / 90634	HGNCID:	25037	Length:	335	Species:	Homo sapiens

Alignment Length:	223	Identity:	78/223 - (34%)
Similarity:	105/223 - (47%)	Gaps:	34/223 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 SGGTHRKYATAEAPSSIRMCPASNLNSNQSNKQFNSICQRAQAGHKLMIIMRGPSGSGKSTLAES 122
            |.|.|| |||.      .:.|       |....:...|.|     .|.||    |...|......
Human   106 SKGFHR-YATG------GIYP-------QEMSTYTQECSR-----YLGII----SEQNKDPALVD 147

  Fly   123 LLRQAHLLDRHQV-RDFVLSSDDYFKTRRG-YVFNPTLLPAAHEWNQQRVRDKAASGWSPIIVDN 185
            |:.|..|  :|.. |..:.|:||:|....| |.|||..|..||||||:|.|....:|.||||:||
Human   148 LMCQRQL--QHDFPRALIFSTDDFFFREDGAYEFNPDFLEEAHEWNQKRARKAMRNGISPIIIDN 210

  Fly   186 TNTMVWEMQPYVQFAVRHGYVIELLEPNTSWCKSASKLAQKNVHNVPRENIQRMLERFER-TTAG 249
            ||...|||:||...|:.:.|.:...||:|.|..:..:||::|:|.|.||.|.||.||:|. .|..
Human   211 TNLHAWEMKPYAVMALENNYEVIFREPDTRWKFNVQELARRNIHGVSREKIHRMKERYEHDVTFH 275

  Fly   250 ELIQLMKETKYSVELPQLRNHPPLPAVP 277
            .::...|.::.:      ||.....|:|
Human   276 SVLHAEKPSRMN------RNQDRNNALP 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7139	NP_649378.1	NK	105..277	CDD:302627	65/174 (37%)
		AAA_33	105..245	CDD:290396	59/141 (42%)
		GluZincin	606..>707	CDD:301352
		DUF1771	812..868	CDD:285756
		SMR	877..960	CDD:214676
N4BP2L1	NP_001340556.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..38
		P-loop_NTPase	46..>103	CDD:328724
		AAA_33	165..269	CDD:330919	50/103 (49%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	121	1.000	Domainoid score	I5690
eggNOG	1	0.900	-	-		E1_KOG2401
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D48413at33208
OrthoFinder	1	1.000	-	-		FOG0001378
OrthoInspector	1	1.000	-	-		otm40831
orthoMCL	1	0.900	-	-		OOG6_106095
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1948
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.750