DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7139 and YPL199C

DIOPT Version :9

Sequence 1:	NP_649378.1	Gene:	CG7139 / 40448	FlyBaseID:	FBgn0027532	Length:	969	Species:	Drosophila melanogaster
Sequence 2:	NP_015125.1	Gene:	YPL199C / 855902	SGDID:	S000006120	Length:	240	Species:	Saccharomyces cerevisiae

Alignment Length:	169	Identity:	43/169 - (25%)
Similarity:	77/169 - (45%)	Gaps:	33/169 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   805 LRDF-----EETRNMAAHHSQLKAECYLKAKQ-------AVQRGNSSVALYYSEIAKLHKQKIDV 857
            :||:     ||.:.:    .:|..|.|.|..|       |.|:|:..:|...||.:|...:..:.
Yeast    15 VRDYNHSTDEEYQRL----RRLADEAYKKRDQLSHESQTAYQQGDKKLAHELSEKSKAQLKTAED 75

  Fly   858 FNQRAANCIMEVHRHTQNNPDLLDLHYLHTVEAISCLD----LFLDRHITVLRNTTRVYKHVFII 918
            ||.:||..:. |..:..::.:.:|||.|:..||:..|.    ..:|.:...|.          :|
Yeast    76 FNMQAAEYVF-VENNADSSSNEIDLHGLYVKEALFILQKRIKFAIDHNEPQLN----------VI 129

  Fly   919 TGRGLHSANGVSTIKNRVKARLGERRLR--WQEVNPGLL 955
            .|:||||.||::.:|..::....:..:|  .::.|.|:|
Yeast   130 VGKGLHSQNGIAKLKPSIEEFCAKHGIRNHLEKGNSGVL 168

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7139	NP_649378.1	NK	105..277	CDD:302627
		AAA_33	105..245	CDD:290396
		GluZincin	606..>707	CDD:301352
		DUF1771	812..868	CDD:285756	16/62 (26%)
		SMR	877..960	CDD:214676	22/85 (26%)
YPL199C	NP_015125.1	DUF1771	28..89	CDD:400763	17/65 (26%)
YPL199C	NP_015125.1	SMR	94..172	CDD:214676	22/85 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2401
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3681
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001378
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1948
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.790