DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG7139 and cnp

DIOPT Version :9

Sequence 1:NP_649378.1 Gene:CG7139 / 40448 FlyBaseID:FBgn0027532 Length:969 Species:Drosophila melanogaster
Sequence 2:XP_009297613.1 Gene:cnp / 325896 ZFINID:ZDB-GENE-030521-29 Length:424 Species:Danio rerio


Alignment Length:553 Identity:111/553 - (20%)
Similarity:177/553 - (32%) Gaps:201/553 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly   283 EESKLLEAPVPAPAENAFKLNANAQTWVPYEHGAPSYWSQTVNSVDTGDATVPEIPDALGAAAPV 347
            |:::.::..||...|.|.:....::   |....||...|:........ ||.||.|.....:|  
Zfish     4 EQNQEVQEAVPETQEVAAQQEEKSE---PKSEEAPQAPSEAAADPPAA-ATEPEKPQEREPSA-- 62

  Fly   348 KSELSIIDLLREENQIKVVPSKAESSGAKPLEMHSLDCPNEPKGFAHLRQMYPNKQLAGLWDLFV 412
                       ||.|      ||..|.|.|.:      |:||:..:                   
Zfish    63 -----------EEQQ------KATESAAPPAK------PSEPEAKS------------------- 85

  Fly   413 KCQADVDWAVDILLKEDELNAATGSDQIGFEE---TIDSEEAAQFQCDCDKAVEAQESPISTPIC 474
                          .||.........|...||   .::||...|.    ::||:..||....|:.
Zfish    86 --------------PEDSSEKTPEQQQKSSEEPSLQVNSEPEKQE----EEAVKEAESKKEEPVK 132

  Fly   475 ASPTLPVSKTESKPQRQPRNKRASAPTNKELQLKIQNCFVLGDEQYSEHTRKIRDIRNGILDQPT 539
            .:.:.|.:..|.||:...:::     |.|....|:|                             
Zfish   133 EADSKPAAVNEVKPEESEKSE-----TTKAEGEKVQ----------------------------- 163

  Fly   540 VPKLLEAPEEPELEEQEEEEDPEENTLLEIDLGGTLIEQLRAQFHTEDELLPPEQELPTATKIFM 604
            ||.......||..|.:.||:.||    |.:..|..|:::             .|:.:..||..|:
Zfish   164 VPDSDGVQAEPPKEAEPEEKKPE----LPLFYGWFLLKE-------------EEERIKCATMDFL 211

  Fly   605 PRQLAKQLYMLWMEAVFNQLEEIRQQTMR--DDEQFARLLKHPGYADC---------SESPSNVA 658
                 |.|..|  ||....:.|...:..:  |.||:   .::|....|         :|.....|
Zfish   212 -----KTLDTL--EAFKEHISEFTSEANKEVDLEQY---FQNPLPLHCTTKFCDYGKAEGAKEYA 266

  Fly   659 ELLDMELAWSIYNSEQLAAKKAAELTARKQTPTDIATHLTKMKLCET----FPD----------- 708
            ||..::.|..  .||:|:      :||...||   .|...::.|.||    :|:           
Zfish   267 ELQVVKEATG--KSEELS------VTALIVTP---RTFGARVALTETQLNLWPEGEDKVGVAPTL 320

  Fly   709 ------VPTDTVLEVF--AATGSNYVQT----VEVL--------------DSNVKSMLSKAELYD 747
                  :|..:...|.  .:.|...|||    :|:|              |....|.||:...| 
Zfish   321 LPGVESLPAGSRAHVTLGCSAGVEAVQTGLDLLEILVLQKEGKEGTQVEMDMGTLSYLSEGRWY- 384

  Fly   748 KALREG-------EKLSEQMALEERRQQQQQKQ 773
            .||||.       ...||...:.::.::..:|:
Zfish   385 LALREAITADTTFSSFSEDKPVSDQGKKDGEKK 417

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7139NP_649378.1 NK 105..277 CDD:302627
AAA_33 105..245 CDD:290396
GluZincin 606..>707 CDD:301352 27/115 (23%)
DUF1771 812..868 CDD:285756
SMR 877..960 CDD:214676
cnpXP_009297613.1 RR_TM4-6 <58..>136 CDD:283990 25/139 (18%)
CNPase 188..402 CDD:283525 51/248 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG2401
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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