DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Act79B and ARP7

DIOPT Version :9

Sequence 1:	NP_001262200.1	Gene:	Act79B / 40444	FlyBaseID:	FBgn0000045	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_015359.1	Gene:	ARP7 / 856146	SGDID:	S000006238	Length:	477	Species:	Saccharomyces cerevisiae

Alignment Length:	462	Identity:	96/462 - (20%)
Similarity:	186/462 - (40%)	Gaps:	114/462 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDCYVG-----DEAQSKRGILSL 68
            :|:.|||....|||:..:.|:.:.||...:...:|     |:.:...|     |.|..||....:
Yeast     8 VVIHNGSHRTVAGFSNVELPQCIIPSSYIKRTDEG-----GEAEFIFGTYNMIDAAAEKRNGDEV 67

  Fly    69 KYPIE-HGIITNWDDMEKVWHHTFYNELRVAPEEHPVLLTEAPLNPK---ANREKMTQIMFETFN 129
            ...:: .|:..|||.:|..|.:.:..:|:|:|||.|:::|....|.|   |..|:..::.|:..|
Yeast    68 YTLVDSQGLPYNWDALEMQWRYLYDTQLKVSPEELPLVITMPATNGKPDMAILERYYELAFDKLN 132

  Fly   130 SPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLM--- 191
            .|...:.|:.:....:.|:::..|:|.|....:..||.:|..:.:|::|....| |..|:.:
Yeast   133 VPVFQIVIEPLAIALSMGKSSAFVIDIGASGCNVTPIIDGIVVKNAVVRSKFGG-DFLDFQVHER 196

  Fly   192 ------------------KILTERGYSFTTTAER--------------EIVRDIKEKLCYVALDF 224
                              |..|:..|..:|..::              |:.|..||:....|...
Yeast   197 LAPLIKEENDMENMADEQKRSTDVWYEASTWIQQFKSTMLQVSEKDLFELERYYKEQADIYAKQQ 261

  Fly   225 EQ--EMATAAASTSL----------EKSYEL-PDGQVITIG-NERFRTPEALFQPSFLG---MES 272
            ||  :|......|:|          :|::.. |..:.:|:. .|.::..|.||:|..:.   ...
Yeast   262 EQLKQMDQQLQYTALTGSPNNPLVQKKNFLFKPLNKTLTLDLKECYQFAEYLFKPQLISDKFSPE 326

  Fly   273 CGIHETVYQSIMKCDVDIR------------------------------------KDLYA----N 297
            .|:...:.:|:.|....|.                                    :.:|:    |
Yeast   327 DGLGPLMAKSVKKAGASINSMKANTSTNPNGLGTSHINTNVGDNNSTASSSNISPEQVYSLLLTN 391

  Fly   298 NVLSGGTTMYPGIADRMQKEITALAP----STIKIKIIAPPERKYSVWIGGSILASLSTFQ-QMW 357
            .:::|.|::..|:..|:.||::...|    :|...:::.  :||...|:|...:|:|.::. ..|
Yeast   392 VIITGSTSLIEGMEQRIIKELSIRFPQYKLTTFANQVMM--DRKIQGWLGALTMANLPSWSLGKW 454

  Fly   358 ISKQEYD 364
            .||::|:
Yeast   455 YSKEDYE 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Act79B	NP_001262200.1	PTZ00281	1..376	CDD:173506	96/462 (21%)
ARP7	NP_015359.1	COG5277	1..471	CDD:227602	96/462 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810