DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Act79B and Ankrd36

DIOPT Version :9

Sequence 1:	NP_001262200.1	Gene:	Act79B / 40444	FlyBaseID:	FBgn0000045	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_076305.2	Gene:	Ankrd36 / 76389	MGIID:	1923639	Length:	1415	Species:	Mus musculus

Alignment Length:	341	Identity:	66/341 - (19%)
Similarity:	106/341 - (31%)	Gaps:	126/341 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 NWDDMEKV--WHHTFYNELRVAPEEHPVLLTEAPL--NPKANREKM---------TQIMFETFNS 130
            |.|.::::  :.|...|...:..|:.|.|.|:.|:  :|......:         ..|.|.  ..
Mouse   289 NTDAVDELGSFAHRPSNSEPIEEEDEPSLSTKPPVVQSPVLTESNLWAGYPADWPEPIKFS--RQ 351

  Fly   131 PAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPI---YEGYALPHAILRL------------- 179
            ||:|...:.                ..|..|.:||:   .:|.|||.....:
Mouse   352 PAVYNPTEW----------------REDMESRSVPLESKQQGAALPGKEANIQTQQQLQTRAFKE 400

  Fly   180 ------DLAGRD-LTDYLMKILTE--------RGYSFTTTA--------EREIVRDIKEKLCYVA 221
                  ||..|: ..|.|:.:|..        :.:..|..|        |||.|.:.:||...:.
Mouse   401 PGANDPDLPSRENAKDELVSLLAPLEEKKPQMKEFPVTEAAKFQTDVKLEREGVLEFEEKGLEIC 465

  Fly   222 LDFEQEMATAAASTSLEKSYELPDGQVITIGNERFRTPEALFQPSFLGMESCGIHETVYQSIMKC 286
            .|...|   ||.||   :||.:          .||..|:                      :...
Mouse   466 QDSNLE---AAEST---ESYSI----------LRFAKPD----------------------VSDP 492

  Fly   287 DVDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTIKIKIIAPPERKYSVWIGGSILASLS 351
            :...|||.|..:...         .||:::.:.|...|..:.|..:||..:         |...|
Mouse   493 EPTARKDEYKLDTKD---------EDRLERHLLAPKASQHQAKQTSPPPVQ---------LQERS 539

  Fly   352 TFQQMWISKQEYDESG 367
            ...:|..:..|.|.||
Mouse   540 QGPEMDTASDEEDTSG 555

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Act79B	NP_001262200.1	PTZ00281	1..376	CDD:173506	66/341 (19%)
Ankrd36	NP_076305.2	Ank_2	37..130	CDD:289560
		ANK repeat	37..64	CDD:293786
		ANK	61..186	CDD:238125
		ANK repeat	68..97	CDD:293786
		ANK repeat	99..130	CDD:293786
		ANK repeat	132..163	CDD:293786
		Ank_2	137..229	CDD:289560
		ANK	162..>240	CDD:238125
		ANK repeat	165..196	CDD:293786
		ANK repeat	198..229	CDD:293786
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900