DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Act79B and Actr6

DIOPT Version :9

Sequence 1:	NP_001262200.1	Gene:	Act79B / 40444	FlyBaseID:	FBgn0000045	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_080190.1	Gene:	Actr6 / 67019	MGIID:	1914269	Length:	396	Species:	Mus musculus

Alignment Length:	408	Identity:	105/408 - (25%)
Similarity:	191/408 - (46%)	Gaps:	56/408 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 SALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDCYVGDEAQSKRGILSLKYP 71
            :.||:|||:...|.|::.|..  :|.|:...|.:...:......:.    ||.:...|:..: .|
Mouse     2 TTLVLDNGAYNAKIGYSHDSV--SVIPNCQFRSKTARLKTFTANQI----DEIKDPSGLFYI-LP 59

  Fly    72 IEHGIITNWDDMEKVWHHTFYNEL-RVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNSPAMYV 135
            .:.|.:.|||...:||.:.|..|: :|...:..:::||...|..:.:|.|.:|:||.:.
Mouse    60 FQKGYLVNWDVQRQVWDYLFGKEMYQVDFLDTNIIITEPYFNFTSIQESMNEILFEEYQ------ 118

  Fly   136 AIQAVLSLYASGRTTG------------IVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTD 188
             .||||.:.|...:..            |::|||...:|.||.........||:|:::.|:.||:
Mouse   119 -FQAVLRVNAGALSAHRYFRDNPSELCCIIVDSGYSFTHIVPYCRSKKKKEAIIRINVGGKLLTN 182

  Fly   189 YLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATA---AASTSLEKSYELPD----- 245
            :|.:|::.|  ......|..::..:||.:|||:.||.::|..|   ....::...|.|||
Mouse   183 HLKEIISYR--QLHVMDETHVINQVKEDVCYVSQDFYRDMDIAKLKGEDNTVMIDYVLPDFSTIK 245

  Fly   246 -------------------GQVITIGNERFRTPEALFQPSFLGMESCGIHETVYQSIMKCDVDIR 291
                               .|::.:.||||..||.||.||.:|::..||.|.:..||.....:::
Mouse   246 KGFCKPREEMVLSGKYKFGEQILRLANERFAVPEILFNPSDIGIQEMGIPEAIVYSIQNLPEEMQ 310

  Fly   292 KDLYANNVLSGGTTMYPGIADRMQKEITALAPSTIKIKIIAPPERKYSVWIGGSILASLSTFQQM 356
            ...:.|.||:||.:::||..:|:..|:..|.|:...:.::.|.......|.||.:::....|:.|
Mouse   311 PHFFKNIVLTGGNSLFPGFRERVYSEVRCLTPTDYDVSVVLPENPITYSWEGGKLISENDDFEDM 375

  Fly   357 WISKQEYDESGPGIVHRK 374
            .:::::|:|:|..:...|
Mouse   376 VVTREDYEENGHSVCEEK 393

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Act79B	NP_001262200.1	PTZ00281	1..376	CDD:173506	105/408 (26%)
Actr6	NP_080190.1	ACTIN	2..394	CDD:214592	105/408 (26%)
Actr6	NP_080190.1	COG5277	2..393	CDD:227602	104/406 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.861654	Normalized mean entropy	S1456
OMA	1	1.010	-	-		QHG54227
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.880