DRSC/TRiP Functional Genomics Resources

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Protein Alignment Act79B and POTEC

DIOPT Version :9

Sequence 1:NP_001262200.1 Gene:Act79B / 40444 FlyBaseID:FBgn0000045 Length:376 Species:Drosophila melanogaster
Sequence 2:NP_001131143.1 Gene:POTEC / 388468 HGNCID:33894 Length:542 Species:Homo sapiens


Alignment Length:267 Identity:50/267 - (18%)
Similarity:89/267 - (33%) Gaps:95/267 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly    14 GSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMV-----GMGQKDCYV---------------GDE 58
            |||....|.:||               |....:     .||:..|:.               ||.
Human    74 GSGTSNVGTSGD---------------HDNSFMKTLRSKMGKWCCHCFPCCRGSGKSNVGAWGDY 123

  Fly    59 AQSKRGILSLKYPIEHGIITNWDDMEKVWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQI 123
            ..|  ..:..:|.:..      :|::|:....::.  :|..::..|:|.:..:| |.:::|.|.:
Human   124 DDS--AFMEPRYHVRR------EDLDKLHRAAWWG--KVPRKDLIVMLRDTDMN-KRDKQKRTAL 177

  Fly   124 MFETFNS-----------------------PAMYVAIQ-----AVLSLYASGRTTGIVLDSGDGV 160
            ...:.|.                       .|:..|:|     .||.|...|....|..:.|:..
Human   178 HLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADQNIPDEYGNTT 242

  Fly   161 SHTVPIYEGYALPHAILRLDLAGRD--------LTDYLMKILTERGYSFTTTAEREIVRD-IKEK 216
            .|.....|...:..|:|   |.|.|        ||..|:.:..::         :::|:. ||:|
Human   243 LHYAVHNEDKLMAKALL---LYGADIESKNKCGLTPLLLGVHEQK---------QQVVKFLIKKK 295

  Fly   217 LCYVALD 223
            ....|||
Human   296 ANLNALD 302

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Act79BNP_001262200.1 PTZ00281 1..376 CDD:173506 50/267 (19%)
POTECNP_001131143.1 ANK 1 138..171 7/35 (20%)
Ank_4 143..193 CDD:290365 8/52 (15%)
ANK 167..292 CDD:238125 25/137 (18%)
ANK 2 172..201 3/28 (11%)
ANK repeat 174..203 CDD:293786 2/28 (7%)
Ank_2 177..269 CDD:289560 17/94 (18%)
ANK repeat 205..236 CDD:293786 8/30 (27%)
ANK 3 205..234 7/28 (25%)
ANK 233..357 CDD:238125 19/82 (23%)
ANK repeat 238..269 CDD:293786 8/33 (24%)
ANK 4 238..267 8/31 (26%)
Ank_2 243..335 CDD:289560 17/72 (24%)
ANK repeat 271..302 CDD:293786 8/39 (21%)
ANK 5 271..300 7/37 (19%)
ANK repeat 304..335 CDD:293786
ANK 6 304..333
ANK 7 337..373
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 369..494
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5277
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_100127
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.710

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