DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Act79B and alp5

DIOPT Version :9

Sequence 1:	NP_001262200.1	Gene:	Act79B / 40444	FlyBaseID:	FBgn0000045	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_595820.1	Gene:	alp5 / 2541318	PomBaseID:	SPBP23A10.08	Length:	433	Species:	Schizosaccharomyces pombe

Alignment Length:	440	Identity:	129/440 - (29%)
Similarity:	205/440 - (46%)	Gaps:	84/440 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 EEASALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDCYVGDE--AQSKRGIL 66
            :|.||:|:|.||...:.||:|:|.|:.|.||..|.       ...|::  ..|:|  .:|..| :
pombe     9 DEVSAIVIDPGSKWTRIGFSGEDIPKCVLPSYCGE-------FSDGRR--LFGEEYIYKSNPG-M 63

  Fly    67 SLKYPIEHGIITNWDDMEKVWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNSP 131
            .:|..|.:|.:.|||....:|.:....:|:..|.|||:|:||...||..||.|..:.|||:...|
pombe    64 EIKNAIRNGWVENWDVTVDLWRYGLEQQLKTNPLEHPILITEPFDNPPENRVKTLETMFESLRCP 128

  Fly   132 AMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTE 196
            |.|:|.|...:.:|||:.|..::|.|...|....||:|:.|.........:|..:.|.|.:.|.:
pombe   129 ATYLAKQETCAAFASGKGTACLVDIGAERSSVSAIYDGFVLQKGYQVQHFSGNAINDILAQTLRD 193

  Fly   197 RGY-------------------------------SFTTTAEREIVRDIKEKLCYVALDFEQEMAT 230
            :.:                               |:.....:.:..:.||:...::     ::..
pombe   194 KNFEVMPKYLVKSKNPVEIGQPANCELRPRDTTDSYHQFQVQRVYDEWKEECALIS-----DVPF 253

  Fly   231 AAASTSLEKSYELPDGQVITIGNERFRTPEALFQP---------------------------SFL 268
            ::.:|..|..:|.|||..:..|.||::.||.||.|                           |..
pombe   254 SSETTIAESEFEFPDGSRMMFGAERYQIPEHLFVPGSDEEMNEEPSKPIEQTENNEVSQQDSSVT 318

  Fly   269 GMES--CGIHETVYQSIMKCDVDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTIKIKII 331
            ...|  .||.:.....|.:||||||..|..|.::.|||::..|.:.|:|.|::.|.|.: ::||.
pombe   319 NTSSRILGIPQLFQNCISECDVDIRASLLNNVIVCGGTSLMQGFSLRLQNELSKLYPGS-RLKIH 382

  Fly   332 AP---PERKYSVWIGGSILASLSTFQQMWISKQEYDESGP---GIVHRKC 375
            |.   .||.|:.|:|||||:||.||.|:|||:|||:|.|.   .::.::|
pombe   383 ASGHVVERSYASWLGGSILSSLGTFHQLWISRQEYEEHGSDRLALIEKRC 432

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Act79B	NP_001262200.1	PTZ00281	1..376	CDD:173506	129/440 (29%)
alp5	NP_595820.1	COG5277	6..425	CDD:227602	128/431 (30%)
alp5	NP_595820.1	Actin	11..433	CDD:278451	128/438 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810