Protein Alignment Act79B and ACTR2

DIOPT Version :9

• Sequence 1: NP_001262200.1
• Gene: Act79B / 40444
• FlyBaseID: FBgn0000045
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_001005386.1
• Gene: ACTR2 / 10097
• HGNCID: 169
• Length: 399
• Species: Homo sapiens
• Alignment Length: 393
• Identity: 177/393 - (45%)
• Similarity: 253/393 - (64%)
• Gaps: 20/393 - (5%)

  Fly     1 MCDEEASALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRP------RHQGVMVGMGQK-DCYVGDE 58
            |..:....:|.|||:|..|.|:||.:.|..:||::||||      :...:.:...:| |..||||
Human     1 MDSQGRKVVVCDNGTGFVKCGYAGSNFPEHIFPALVGRPIIRSTTKVGNIEIKNNKKMDLMVGDE 65

  Fly    59 AQSKRGILSLKYPIEHGIITNWDDMEKVWHHTFYNE-LRVAPEEHPVLLTEAPLNPKANREKMTQ 122
            |...|.:|.:.||:|:||:.|||||:.:|.:||..| |.:......:||||.|:||..||||:.:
Human    66 ASELRSMLEVNYPMENGIVRNWDDMKHLWDYTFGPEKLNIDTRNCKILLTEPPMNPTKNREKIVE 130

  Fly   123 IMFETFNSPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLT 187
            :||||:....:||||||||:|||.|..||:|:||||||:|..|:|||::|||...|||:||||:|
Human   131 VMFETYQFSGVYVAIQAVLTLYAQGLLTGVVVDSGDGVTHICPVYEGFSLPHLTRRLDIAGRDIT 195

  Fly   188 DYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAAASTSLEKSYELPDGQVITIG 252
            .||:|:|..|||:|..:|:.|.||.||||||||..:.|||...|..:|.|.:||.||||::|.:|
Human   196 RYLIKLLLLRGYAFNHSADFETVRMIKEKLCYVGYNIEQEQKLALETTVLVESYTLPDGRIIKVG 260

  Fly   253 NERFRTPEALFQPSFLGMESCGIHETVYQSIMKCDVDIRKDLYANNVLSGGTTMYPGIADRMQKE 317
            .|||..|||||||..:.:|..|:.|.::.:|...|:|.|.:.|.:.|||||:|||||:..|:::|
Human   261 GERFEAPEALFQPHLINVEGVGVAELLFNTIQAADIDTRSEFYKHIVLSGGSTMYPGLPSRLERE 325

  Fly   318 ITAL-----------APSTIKIKIIAPPERKYSVWIGGSILAS-LSTFQQMWISKQEYDESGPGI 370
            :..|           ..|..||:|..||.||:.|::||::||. :......|:::|||.|.|..:
Human   326 LKQLYLERVLKGDVEKLSKFKIRIEDPPRRKHMVFLGGAVLADIMKDKDNFWMTRQEYQEKGVRV 390

  Fly   371 VHR 373
            :.:
Human   391 LEK 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Act79B	NP_001262200.1	PTZ00281	1..376	CDD:173506	177/393 (45%)
ACTR2	NP_001005386.1	ACTIN	6..393	CDD:214592	176/386 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820