Protein Alignment CG7470 and ALDH7A1

DIOPT Version :9

• Sequence 1: NP_001246877.1
• Gene: CG7470 / 40443
• FlyBaseID: FBgn0037146
• Length: 776
• Species: Drosophila melanogaster
• Sequence 2: NP_001173.2
• Gene: ALDH7A1 / 501
• HGNCID: 877
• Length: 539
• Species: Homo sapiens
• Alignment Length: 571
• Identity: 113/571 - (19%)
• Similarity: 188/571 - (32%)
• Gaps: 152/571 - (26%)

  Fly   263 PWEDGAKLMHTYTSDDSNSIEFGKKSKVGTGGMDSKVKAATWALDRGVSVVICNGMQEKAIKTII 327
            ||...|..|.|..   .|..::....::|....:..|...:|.....|....|....|...:
Human    21 PWSRPAAFMSTLL---INQPQYAWLKELGLREENEGVYNGSWGGRGEVITTYCPANNEPIAR--- 79

  Fly   328 GGRKVGTFFTEATESANAVPVEVMAENARTGSRQMQALTPAQRASAVNTLADLLVSREKFILDAN 392
                        ...|:....|...:.||...:....:...:|...|..:.|.|  |||.
Human    80 ------------VRQASVADYEETVKKAREAWKIWADIPAPKRGEIVRQIGDAL--REKI----- 125

  Fly   393 AKDLAEAQKSGLAKPLLSRLSLNPAKLKNLSVGLKQIAED--------SHKNVGRVLRRTRLADQ 449
                         :.|.|.:||...|:....||..|...|        |....|.:|...|....
Human   126 -------------QVLGSLVSLEMGKILVEGVGEVQEYVDICDYAVGLSRMIGGPILPSERSGHA 177

  Fly   450 LELKQVTVPIGVLLVIFESRPDSLPQVA-----ALAMASANGLLLKGGKEAAHSNKALMELVKEA 509
            | ::|.. |:|::.:|   ...:.|...     |:||...|..|.||....:..:.|:.:::.:.
Human   178 L-IEQWN-PVGLVGII---TAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKV 237

  Fly   510 LATVGAEHAV-SLVSTREEISDLLSMENHIDLIIPRGSSDLVRSI-----QQQSLHIPVLGHAEG 568
            |.......|: ||.....:|...::.:..::|:...||:.:.:.:     ::....:..||   |
Human   238 LEDNKLPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLMVQERFGRSLLELG---G 299

  Fly   569 VCHVYIDRDADLEKALRIARDAKCDYPAA-----------CNAMETLLIHEDLMSGAIFGDVCNM 622
            ...:....||||...:          |:|           |.....|.|||     :|..:|.|.
Human   300 NNAIIAFEDADLSLVV----------PSALFAAVGTAGQRCTTARRLFIHE-----SIHDEVVNR 349

  Fly   623 LKREGVKIYAGPRLNQQLTFGP-----------PAAKSLKHEYGALECCIEVV--------PSL- 667
            ||:...:|..|...:..:.:||           .|.:..|.|.|.:....:|:        |::
Human   350 LKKAYAQIRVGNPWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIV 414

  Fly   668 -----DEAINHIHTYG--------SSHTDVIVTENDAAARQFLGSVDSACVFHNASSRFADGFRF 719
                 |.:|.|..|:.        .:..:|....|:  .:|.|    |:.:|.....|.   ||:
Human   415 TGLGHDASIAHTETFAPILYVFKFKNEEEVFAWNNE--VKQGL----SSSIFTKDLGRI---FRW 470

  Fly   720 --GLGAEVGISTARIHARGPV--GVEGLLTTKWILEGQDHAAADFAEGGGR 766
              ..|::.||....|...|..  |..|         |:.|.      ||||
Human   471 LGPKGSDCGIVNVNIPTSGAEIGGAFG---------GEKHT------GGGR 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7470	NP_001246877.1	AAK_P5CS_ProBA	49..337	CDD:239789	12/73 (16%)
		P5CS	50..775	CDD:130164	113/571 (20%)
		ALDH_F18-19_ProA-GPR	349..753	CDD:143398	94/470 (20%)
ALDH7A1	NP_001173.2	ALDH_F7_AASADH	53..527	CDD:143448	106/536 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910