Protein Alignment Chs2 and chs2

DIOPT Version :10

• Sequence 1: NP_524209.3
• Gene: Chs2 / 40442
• FlyBaseID: FBgn0029091
• Length: 1393
• Species: Drosophila melanogaster
• Sequence 2: XP_073785914.1
• Gene: chs2 / 563347
• ZFINID: ZDB-GENE-060503-320
• Length: 1249
• Species: Danio rerio
• Alignment Length: 1395
• Identity: 452/1395 - (32%)
• Similarity: 668/1395 - (47%)
• Gaps: 307/1395 - (22%)

  Fly    10 DYFMRSRKQ----RDKPSLWDSFQDPPSKKTSGSDADWKKLQFCLKLFKICTY--LLVFAVVLAT 68
            |...:..||    ..:...||..::.|..:.....   ||...|||.| .||.  ||||.:.|.:
Zfish    12 DVHKKEHKQDEQKEQEQKFWDVCREVPIIQNEQMP---KKRMHCLKWF-ACTVVGLLVFILALLS 72

  Fly    69 SVFANLIYLYMAGNTGGTGPRVQVCSKYPVLRHGQVEAVASELDQIAWVWALIFAFAAPELLTFL 133
            .  .:.:.|...||                   .|.:.:.|:....| :.|:.|....|.:|..|
Zfish    73 K--TSFLLLITFGN-------------------NQTDIIHSDKKPTA-LLAIGFVLVGPNVLLLL 115

  Fly   134 RALRICMFKREQRPSGLEVGLVTLFELLHVVGLALLTFTVLPALDVTRGAILGCCVCFVPALLNL 198
            ::....:||....|:...|..|...|:|..:|.|:||...:|..|:....::...|..:.|:..:
Zfish   116 KSTWKFIFKSATMPAKKTVFWVLCVEILVALGAAVLTIVAMPHFDIVTNVMILNSVSILSAVFQV 180

  Fly   199 LTGTRVRWRSADSLVLGLSILALVAQGSV-----FLVWPSLSDSMEVQLLAIPLLLISFRWWENF 258
            :.....:.|....::..|||:.:|. |.|     :||:.| |..:.:.|.....:.:|..||||:
Zfish   181 VAECLAKERKRLIMLPVLSIIFIVL-GYVLFVVNYLVFES-SFCITIGLAIFGTICVSMNWWENY 243

  Fly   259 ANTHEAIAY--IIRTIRCTRSRYHTYLYLAPLKVLVFAGMGFILHGHEFVEYFGRFRDAWRPHLI 321
            :....::..  |.:.|..:|:..:....|..: ::..|.:|      .:|...|   |.|
Zfish   244 STLFNSLHLKGISKDIGKSRNAVNIISSLTRI-LITSAVIG------AYVTLTG---DGW----- 293

  Fly   322 TLVQSNGDPDALLLAQANVSITAPPRRTLFTMQSSPNSVFYALAAQVGAAYLCHIFGKFACKIKI 386
                     :::.|....|.|.....:||                   ::.||..|...|||:..
Zfish   294 ---------NSVKLVFETVVIALVVIQTL-------------------SSALCRWFVVVACKMHA 330

  Fly   387 QKFSYALPLSLAGPATVCLVTFLAQLRASDPCSLHGFMP--------DYLSLLALGGSVEEL--- 440
            .:.|:.:|:..|  :.:.|..||:.|....|.|.:..:|        :::.|| |..:::.|
Zfish   331 LRRSFFMPMYFA--SVIVLAVFLSPLVVKFPVSNYTSIPLDKSESSVEWVKLL-LADAIKTLLTR 392

  Fly   441 ---------GQRCLD-YALWLWPLWWLAQVWTCLHIWQPHNDRNAPTEKLFVCPWYCGLLVDQCS 495
                     |..||. .||:    |||..|.:.::||.....|...|:.|||...|.|..::|..
Zfish   393 DIVVNMKTEGLVCLGCSALF----WWLGLVLSTVYIWFLKIHRIERTQDLFVQRMYEGAFLEQSL 453

  Fly   496 MMNRRIVDWSEEYLAIKSDLTAPRDPVVALAADINASRDIQEEDKVPQLI---VCATMWHETEDE 557
            ::|.|        ..|:..:                     ::.|..|:|   :||||||||.||
Zfish   454 LLNTR--------FEIRKKI---------------------KDKKCAQIIRVFLCATMWHETYDE 489

  Fly   558 MMEFLKSIVRLDEDQCARRMARTHLNGGKADDEYYELETNIFFDDAFVSDPRQCQNKRNPPINEY 622
            ||:.:.|:.|||    |.| .:|    ||..|  .|.|.:::|||||..|    .|:|....|||
Zfish   490 MMKIIISMFRLD----AYR-PKT----GKHSD--IEFEFHVYFDDAFKDD----SNQRERLANEY 539

  Fly   623 VKTLTRTIDKAAFEVYGVNIRIKP-------PLK----IETPYGGRLVWTLPGRTKMVAHLKNKD 676
            |:.|...|.    |||.:.....|       ||.    |.|||||||.:|||....|:.|||:|.
Zfish   540 VEILVEVIK----EVYIIFSEEDPCVFKKMQPLPTQKIISTPYGGRLEYTLPKGNVMMVHLKDKQ 600

  Fly   677 KIRHKKRWSQVMYMYYLLGYRIME--------------TKELSPRRKAVIAENTFILALDGDIDF 727
            .|||||||||:||:||:||:|:.:              .||...|.:    |||:|||||||.||
Zfish   601 LIRHKKRWSQIMYLYYILGWRLNKQYYEKFEAGEEPDLLKEKLKRER----ENTYILALDGDTDF 661

  Fly   728 QPRAVRLLIDRMKAVDELGAACGRIHPVGRGPMVWYQRFEYAIGHWLQKATEHVIGCVLCSPGCF 792
            ||.||.|||||:|...|:|||||||||.|.|||||||:||||:||||||..|||.||||||||||
Zfish   662 QPSAVMLLIDRLKLYPEVGAACGRIHPTGTGPMVWYQKFEYAVGHWLQKTAEHVFGCVLCSPGCF 726

  Fly   793 SLFRASALMENSVMKRYTMISSEAMKMVQYDQGEDRWLCTLLLKAGSRVEYCAASDAYTHAPESF 857
            ||||.:||:|::||||||..:|||...||||||||||||||||:.|.||||.|||||||:||:.|
Zfish   727 SLFRGAALVEDNVMKRYTTKASEASHYVQYDQGEDRWLCTLLLQQGWRVEYNAASDAYTNAPQDF 791

  Fly   858 NEFYNQRRRWVPSTIANIFDILADADTVVKKNNSISTMYVWYQGMLMIGTVLGPGTIFLMMVGAL 922
            .|||||||||.|||:||..|:|.......::|:|||.:|:.||.:.|..::|||.||.||:.|:.
Zfish   792 KEFYNQRRRWGPSTMANTIDLLGSGQLTSQRNSSISKLYILYQIISMAASILGPATICLMISGSF 856

  Fly   923 VAVFSIDIWTAFLWNFFPILLFILACVYLKQKFQLLIAFVISSVYCLVMMAVLIGIIVQMLEDGP 987
            |.:|:::..||......|..::::.|..||...|:.||.::|.:|..:|...::.||..:::...
Zfish   857 VFIFNMNENTALALAIVPPTVYLILCFKLKSDTQIRIAAIMSIIYAFLMAGTILSIIGDLVKQNT 921

  Fly   988 -LAPASLFFLLVAVQITIAGFMHPQEFWALLCGVIYYITIPSMYMLLMIFSVFNMNDVSWGTREA 1051
             |.|:.||.:.:.:...|...:|||||..::.|::|:|.|||.|:||.|:|:.|||:|||||||:
Zfish   922 FLTPSGLFLIGMVMLYVITAALHPQEFSLVVYGLLYFICIPSGYLLLAIYSIVNMNNVSWGTRES 986

  Fly  1052 ------------------------PVLKDDGKDAVD-------------------EANNYLPGWL 1073
                                    |.|:.:.:.:.:                   ::.|..|
Zfish   987 GGQTKTSAVNSLKKKFMNATCCKCPCLEYEDETSKEILPAETITKTETSQITLDIQSANVFP--- 1048

  Fly  1074 NDPLLID-------------------SELGEVSLMEQRFWKDLIKQYLKPLELSREQKQAMADGL 1119
            ..|..:|                   ||. ::|..|..||.::..:||:||..::||::.:|:.|
Zfish  1049 TSPYSLDRKPWIQRLQPKFGFWLKSKSEC-KLSTDEVSFWMEMQNKYLEPLMENKEQQEKIANDL 1112

  Fly  1120 KELRNMIAFAFVMVNAIFVLIVFLLQLKKEFLHLEWP-IDP------TDFVSFDRDNLMVGIYRQ 1177
            :||||.:.|.|...||:::...|.||...:.:.::.| |.|      |:.:|
Zfish  1113 RELRNKVTFVFFFCNALWLAATFFLQTIGDAVSIKIPKIYPNGTHSSTETLS------------- 1164

  Fly  1178 YKELDPIGLCFVIFFGLILIIQFLAMFFHRFATLCQLLATTQVDWFRTGGQFTDEDAATELKGSA 1242
               ||||.|.|::.|.::||:|||.|.:||..||...:|.                |.||:|..
Zfish  1165 ---LDPIALMFLLSFAVLLIMQFLGMLYHRIYTLIHYVAY----------------ADTEIKAH- 1209

  Fly  1243 VSIARKLQRPKRLFDDDEDGDPHYDEVLMD 1272
               .::.::..::.|.:     |:.|...|
Zfish  1210 ---RKQSEQVAQIVDSN-----HHQETTED 1231

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Chs2	NP_524209.3	Chitin_synth_C	546..874	CDD:133033	201/352 (57%)
		BcsA	<789..976	CDD:440828	97/186 (52%)
		SLC5-6-like_sbd	903..>1055	CDD:444915	57/176 (32%)
chs2	XP_073785914.1	None