Protein Alignment Chs2 and Has3

DIOPT Version :10

• Sequence 1: NP_524209.3
• Gene: Chs2 / 40442
• FlyBaseID: FBgn0029091
• Length: 1393
• Species: Drosophila melanogaster
• Sequence 2: NP_032243.2
• Gene: Has3 / 15118
• MGIID: 109599
• Length: 554
• Species: Mus musculus
• Alignment Length: 507
• Identity: 96/507 - (18%)
• Similarity: 171/507 - (33%)
• Gaps: 188/507 - (37%)

  Fly   603 AFVSDPRQCQNKRNPPINEYVKTLTRTIDKAAFEVYGVNIRIKPPLKI----------------- 650
            |:..||            ||::...|:..:.||          |.||:
Mouse    94 AYQEDP------------EYLRKCLRSAQRIAF----------PNLKVVMVVDGNRQEDTYMLDI 136

  Fly   651 ------ETPYGGRLVWTL----PGRTKMVAHL-KNKDKIRH----------KKRWS---QVMYMY 691
                  .|...|..||..    .|..:..|.| :..:::|.          .::|.   :|||..
Mouse   137 FHEVLGGTEQAGFFVWRSNFHEAGEGETEASLQEGMERVRAVVWASTFSCIMQKWGGKREVMYTA 201

  Fly   692 YLLGYRIMETKELSPRRKAVIAENTFILALDGDIDFQPRAVRLLIDRMKAVDE---LGAACGRIH 753
            :                ||:.....:|...|.|....|...   |:.::.::|   :|...|.:.
Mouse   202 F----------------KALGNSVDYIQVCDSDTVLDPACT---IEMLRVLEEDPQVGGVGGDVQ 247

  Fly   754 PVGRGPMVWYQRFEYAIGHWL----QKATEHVIGCVLCSPGCFSLFRASALMENSVMKRY----- 809
            .:.:... |.. |..::.:|:    ::|.:...|||.|..|...::|      ||:::::
Mouse   248 ILNKYDS-WIS-FLSSVRYWMAFNVERACQSYFGCVQCISGPLGMYR------NSLLQQFLEDWY 304

  Fly   810 --TMISSEAMKMVQYDQGEDRWLCTLLLKAGSRVEYCAASDAYTHAPESFNEFYNQRRRWVPSTI 872
              ..:.|:.      ..|:||.|...:|..|.|.:|.|.|...|..|..:..:.||:.||
Mouse   305 HQKFLGSKC------SFGDDRHLTNRVLSLGYRTKYTARSKCLTETPTRYLRWLNQQTRW----- 358

  Fly   873 ANIFDILADADTVVKKNNSISTMY--VWYQ----GMLMIGTVLGPGTIFLMMVGALVAVFSIDIW 931
                          .|:.....:|  :|:.    .|.....|.|....||  :..::.:|    :
Mouse   359 --------------SKSYFREWLYNSLWFHKHHLWMTYESVVTGFFPFFL--IATVIQLF----Y 403

  Fly   932 TAFLWNFFPILLFIL------------ACVYLKQKFQLLIAFVISSVYCLVMMAVLIGIIVQMLE 984
            ...:||   ||||:|            || :|:...::    :..|:|.|:.|:.|:
Mouse   404 RGRIWN---ILLFLLTVQLVGIIKATYAC-FLRGNAEM----IFMSLYSLLYMSSLL-------- 452

  Fly   985 DGPLAPASLFFLLV------------AVQITIAGFMHPQEFW-ALLCGVIYY 1023
                 ||.:|.:..            .:.:...|.: |...| |:|.|.:.|
Mouse   453 -----PAKIFAIATINKSGWGTSGRKTIVVNFIGLI-PVSIWVAVLLGGLAY 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Chs2	NP_524209.3	Chitin_synth_C	546..874	CDD:133033	62/325 (19%)
		BcsA	<789..976	CDD:440828	44/211 (21%)
		SLC5-6-like_sbd	903..>1055	CDD:444915	30/146 (21%)
Has3	NP_032243.2	GT2_HAS	87..365	CDD:133056	63/344 (18%)