Protein Alignment CG7458 and TPO3

DIOPT Version :10

• Sequence 1: NP_649374.1
• Gene: CG7458 / 40441
• FlyBaseID: FBgn0037144
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: NP_015482.1
• Gene: TPO3 / 856279
• SGDID: S000006360
• Length: 622
• Species: Saccharomyces cerevisiae
• Alignment Length: 577
• Identity: 117/577 - (20%)
• Similarity: 186/577 - (32%)
• Gaps: 187/577 - (32%)

  Fly    78 STVVHRCTVPQCD---SPSSVYEEDWLGFTIPKKNSAWDD--CHRYAANISDAISGYT----DPS 133
            ||.:.|....|.|   ||||  .||.|.....:|....|.  .:..|.::...|...|    ||.
Yeast   106 STAISRTRTRQIDGASSPSS--NEDALESDNNEKGKEGDSSGANDEAPDLDPEIEFVTFVTGDPE 168

  Fly   134 GQY----CLKEYFTITSETCGRDFKFRDEEKTISTEFGIYC--------EDEWKLSMVGTINNVG 186
            ..:    .::..:|:.....           .|...:|..|        |.::.:.|...|.:|.
Yeast   169 NPHNWPAWIRWSYTVLLSIL-----------VICVAYGSACISGGLGTVEKKYHVGMEAAILSVS 222

  Fly   187 -QFVGIPLGGYF----ADRYGRRTMLAVAGSVSALMGVIRSLSSNYSMFLVFEFLD--------M 238
             ..:|..||...    :|.||||....|:..:..:..:..:|:.|....|...||.        .
Yeast   223 LMVIGFSLGPLIWSPVSDLYGRRVAYFVSMGLYVIFNIPCALAPNLGSLLACRFLCGVWSSSGLC 287

  Fly   239 AVGST---LFPT-------AFLLAIELVGPKRRVAAATIITIFYALGEAFLGFLASQVQHWRWLL 293
            .||.:   :||:       ||......|||              .:|....||::
Yeast   288 LVGGSIADMFPSETRGKAIAFFAFAPYVGP--------------VVGPLVNGFIS---------- 328

  Fly   294 RVLYAPAVLQILFLWI--LPESVRWLLSQGAEEKASNVL--RRAARINQRPLPEEQLNDLLTSNR 354
               .:...:.::| |:  ....|.|::|....|..:.|:  |:|||:.:.           |.|
Yeast   329 ---VSTGRMDLIF-WVNMAFAGVMWIISSAIPETYAPVILKRKAARLRKE-----------TGN- 377

  Fly   355 QKLSQANESQ----YPIMRAV----VFFSLR----IANC---CLCW-------FTHTLI------ 391
            .|:....|:|    ..:|||.    ::||:.    :|.|   ||.:       |...:|
Yeast   378 PKIMTEQEAQGVSMGEMMRACLLRPLYFSVTEPVLVATCFYVCLIYSLLYAFFFAFPVIFGELYG 442

  Fly   392 ----ALGLSLNSVNLGG-----------NKYTNF-----------MLNGFIQIPGLLLPLVIMDR 430
                .:||....:.:|.           |||...           :|...|..|...:.|.|:..
Yeast   443 YKDNLVGLMFIPIVIGALWALATTFYCENKYLQIVKQRKPTPEDRLLGAKIGAPFAAIALWILGA 507

  Fly   431 VGRRHSLCASMLLCAICMGASAAVPADNYAGSLALFLIGKLAITCSFQILYFFTSEIFPTNVRNT 495
            ...:|         .|.:|.::|..|..:...|..:.:....|.|..|    :.|....|.|
Yeast   508 TAYKH---------IIWVGPASAGLAFGFGMVLIYYSLNNYIIDCYVQ----YASSALATKV--- 556

  Fly   496 LLSLCSMVGRIGSMLAPQTPLLAKYYIYAPQILFATFALISGFLTLAFPETADKVLP 552
              .|.|..|             |.:.::..| ::....|..|...|||..||...||
Yeast   557 --FLRSAGG-------------AAFPLFTIQ-MYHKLNLHWGSWLLAFISTAMIALP 597

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7458	NP_649374.1	MFS_SLC22	150..544	CDD:340875	92/482 (19%)
TPO3	NP_015482.1	MFS_Tpo1_MDR_like	182..608	CDD:340881	98/499 (20%)