DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7458 and OCT3

DIOPT Version :9

Sequence 1:	NP_649374.1	Gene:	CG7458 / 40441	FlyBaseID:	FBgn0037144	Length:	572	Species:	Drosophila melanogaster
Sequence 2:	NP_173089.1	Gene:	OCT3 / 838209	AraportID:	AT1G16390	Length:	518	Species:	Arabidopsis thaliana

Alignment Length:	570	Identity:	132/570 - (23%)
Similarity:	222/570 - (38%)	Gaps:	117/570 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 SLDAILVR-IGQFGRYQIINYVLLCVPMLFNAFFSISYVFTASTVVHRCTVPQ-----CDSPSSV 95
            ||:..:.| ||.||..|.:...|:.....|:|..:...|||.|..:..|....     |::.||.
plant    24 SLEETIERCIGDFGWAQFLQAALVSFAWFFDAQQTFITVFTDSQPMWHCDNSDRVDSVCNTSSSN 88

  Fly    96 YEEDWLGFTIPKKNSAWDDCHRYAANISDAISGYTDPSGQYCLKEYFTITSETCGRDFKFRDEEK 160
            .      .|:|.:..:||                        |..:.:|.|
plant    89 L------CTLPNQTWSWD------------------------LNPHVSIIS-------------- 109

  Fly   161 TISTEFGIYCEDEWKLSMVGTINNVGQFV-GIPLGGYF-------------AD-RYGRRTMLAVA 210
                |:|:.|              .|.|: |.|...:|             || ..||:.||.::
plant   110 ----EWGLQC--------------AGSFLKGFPASSFFLGCLIGGLALSTLADSSLGRKNMLLLS 156

  Fly   211 GSVSALMGVIRSLSSNYSMFLVFEFLDMAVGSTLFPTAFLLAIELVGPKRRVAAATIITIFYALG 275
            ..:.:|..::.:.|::..::....||:....:|:...|.:|:.||||.|.|.....:....:.||
plant   157 CLIMSLSSMLTAFSTSIWVYAFLRFLNGCGRATIGTCALVLSTELVGKKWRGQVGAMGFFCFTLG 221

  Fly   276 ---EAFLGFLASQVQHWRWLLRVLYAPAVLQ-ILFLWILPESVRWLLSQGAEEKASNVLR----R 332
               ...||:: ::...||.|......|.::. .|....:.||.|||:.:|.:|:|.::|:    .
plant   222 FLSLPMLGYI-NEGNSWRNLYVWTSIPTLIYCCLVRSFVRESPRWLIVKGRKEEAVSILQSIASN 285

  Fly   333 AARINQRPLPEEQLNDLLTSNRQKLSQANESQYPIMRAVVFFS---LRIANCCLCWFTHTLIALG 394
            |..::...|..|..||        .|::|...|..::.:|..|   .|:....:..|...::..|
plant   286 AITMSFTNLCFEVEND--------QSKSNPDVYDALKILVRKSWSFRRLLAAMVVGFGIGMVYYG 342

  Fly   395 LSLNSVNLGGNKYTNFMLNGFIQIPGLLLPLVIMDRVGRRHSLCASMLLCAICMGASAAVPA--D 457
            :.|...||..|.|...:.|...:.|..|:....:|::.||.:|.....|    .|.|:|:.|  .
plant   343 MPLALTNLNFNLYLGVVFNALSEFPAFLITFFFIDKINRRDALIGFTAL----SGISSALIAVLG 403

  Fly   458 NYAGSL--ALFLIGKLAITCSFQILYFFTSEIFPTNVRNTLLSLCSMVGRIGSMLAPQTPLLAK- 519
            ...|||  .|.|:...:...:|.:...:|.|:|||.|||:.:|:.......|.:.:|......:
plant   404 QQLGSLQIVLELVSFFSACTAFNMTLIYTIEMFPTCVRNSAISMVRQALVFGGVFSPVMVAAGRE 468

  Fly   520 --YYIYAPQILFATFALISGFLTLAFPETADKVLPTTIEEARDLNQAKRR 567
              ::.|.   ||.....:.|......|||...||..|::|......|||:
plant   469 NQFWSYG---LFGLIIGLCGLFVFGLPETRGSVLCDTMDEEEYKTLAKRQ 515

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7458	NP_649374.1	2A0119	46..554	CDD:273328	123/545 (23%)
CG7458	NP_649374.1	MFS	161..544	CDD:119392	96/415 (23%)
OCT3	NP_173089.1	MFS_OCT_plant	87..492	CDD:340936	104/482 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	1	1.010	-	-		D762280at2759
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.030