DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7458 and OCT4

DIOPT Version :9

Sequence 1:	NP_649374.1	Gene:	CG7458 / 40441	FlyBaseID:	FBgn0037144	Length:	572	Species:	Drosophila melanogaster
Sequence 2:	NP_188702.2	Gene:	OCT4 / 821613	AraportID:	AT3G20660	Length:	526	Species:	Arabidopsis thaliana

Alignment Length:	562	Identity:	150/562 - (26%)
Similarity:	253/562 - (45%)	Gaps:	89/562 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 AGGDEDNSLDAILVR-IGQFGRYQIINYVLLCVPMLFNAFFSISYVFTASTVVHRCTVPQCDSPS 93
            |.|:|...:|.:|.| .|:|||:|:.::||.|:.....||.::..:|.......||....|...|
plant    26 AEGEERLCIDEMLQRYCGEFGRWQLKHFVLTCIAWALEAFHTMVMIFADQEPEWRCVGSDCRVGS 90

  Fly    94 SVYEEDWLGFTIPKKNSAWDDCHRYAANISDAISGYTDPSGQYCLKEYFTITSETCGRDFKFRDE 158
            ...|.|         .|:|:                                 .|.|:.
plant    91 LNCELD---------PSSWE---------------------------------WTAGKG------ 107

  Fly   159 EKTISTEFGIYCEDEWKLSMVGTINNVGQFVGIPLGGYFAD-RYGRRTMLAVAGSVSALMGVIRS 222
            ..|:| |:|:.|.|::|:.:|..:...|..:|..:.|:.:| :.||:..|.|...::|:.|:..:
plant   108 SSTVS-EWGLICGDKYKVGLVQALFFAGCMIGAGVFGHLSDSKLGRKGSLTVVCIINAIFGIATA 171

  Fly   223 LSSNYSMFLVFEFLDMAVGSTLFPTAFLLAIELVGPKRRVAAATIITIFYALGEAFLGFLASQVQ 287
            .|.||..::|..||.......:..|||:||.|.:||.:|..|......|::.|.|.|..:|...:
plant   172 FSPNYWTYVVLRFLTGFSTGGVGLTAFVLATEPIGPSKRGVAGMSTFYFFSAGIAVLSGIAYVFR 236

  Fly   288 HWRWLLRVLYAPAVLQILFLWILP---ESVRWLLSQGAEEKASNVLRRAARINQRPLPEE---QL 346
            .||.|..|...|::|.:|.  ::|   ||.||.|.:|..::|..::...|:.|.|.:|..   .|
plant   237 SWRELFIVSSLPSLLFLLI--VIPFISESPRWYLVRGKVDEAMKLMHSIAKTNGRHIPAGVTLAL 299

  Fly   347 NDLLTSNRQKLSQANESQY------PIMRAVVFFSLRIANCCLCWFTHTLIALGLSLNSVNLGGN 405
            :|.:.:|..:.:.|.|...      |:||..:..|:.|:      ||.:::..|||||..||..|
plant   300 DDDVENNNGERNTAVEGSLKDVILSPLMRMRLVISVAIS------FTVSIVYYGLSLNVGNLKTN 358

  Fly   406 KYTNFMLNGFIQIPGLLLPLVIMDRVGRRH-SLCASMLLCAICM------GASAAVPADNYAGSL 463
            .|.|..:|...::|...:..|::|:.||:. |:......|..|:      ||.........:|.|
plant   359 LYLNVFVNAVSEMPAFAITAVLLDKYGRKPLSIGTQWFSCVFCLVGFSVWGAGPWKSVRMVSGVL 423

  Fly   464 ALFLIGKLAITCSFQILYFFTSEIFPTNVRNTLLSLCSMVGRIGSMLAPQTPLLAKYYIYAPQIL 528
            .:|     .:..::.:|:.:.:|:|||.|||..|...:...::|::|||...:|.:   ..|..:
plant   424 GIF-----GMAGTYNLLFIYIAELFPTVVRNAALGCATQAAQMGAILAPFVVVLGE---ELPFGV 480

  Fly   529 FATFALISGFLTLAFPETADKVLPTTIEEARDLNQAKRRSER 570
            ||...|:.|.|....|||.:|.|..|:   ..:::|:..|.|
plant   481 FAVCGLVGGGLAFYLPETLNKPLYDTM---FGMHEAESESNR 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7458	NP_649374.1	2A0119	46..554	CDD:273328	140/527 (27%)
CG7458	NP_649374.1	MFS	161..544	CDD:119392	114/402 (28%)
OCT4	NP_188702.2	MFS_OCT_plant	90..496	CDD:340936	121/470 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010