Protein Alignment CG7458 and slc22a21

DIOPT Version :9

• Sequence 1: NP_649374.1
• Gene: CG7458 / 40441
• FlyBaseID: FBgn0037144
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: NP_001295487.1
• Gene: slc22a21 / 799908
• ZFINID: ZDB-GENE-091118-62
• Length: 546
• Species: Danio rerio
• Alignment Length: 543
• Identity: 156/543 - (28%)
• Similarity: 270/543 - (49%)
• Gaps: 39/543 - (7%)

  Fly    45 IGQFGRYQIINYVLLCVPMLFNAFFSISYVFTASTVVHRCTVPQCDSPSSVYEEDWLGFTIPKKN 109
            :|.:|.:|...:.|||:.::.|.|..:|.||...|..|.|.:|:..:.::    .|...::|:..
Zfish    13 LGAWGPFQKTVFSLLCLSIIPNGFTGLSIVFLGDTPAHHCRIPETLNLTA----GWRNASVPRPQ 73

  Fly   110 SAWDD----CHRYAANISDAISGYTD----PSGQYCLKEYFTITSETCGRDFKFRDE--EKTIST 164
            ...|.    |:|...   |.:..|:|    |.....:.|   |..|.|...:.:..|  ..||.:
Zfish    74 PHGDPRASRCYRLRL---DLVKNYSDGGLLPGLDVNVSE---IPREECADGWIYDKEIYSSTIVS 132

  Fly   165 EFGIYCEDEWKLSMVGTINNVGQFVGIPLGGYFADRYGRRTMLAVAGSVSALMGVIRSLSSNYSM 229
            |:.:.|.|:||..:..:|...|...|..:.|..:||:||:.:|.|..::..|..|::..|.::.:
Zfish   133 EWDLVCSDDWKSPLTSSIFFCGVLTGSVISGPVSDRFGRKIVLFVTMAIQTLFTVVQVFSPSWQI 197

  Fly   230 FLVFEFLDMAVGS-TLFPTAFLLAIELVGPKRRVAAATI-ITIFYALGEAFLGFLASQVQHWRWL 292
            | .|.|..:.:|. :.:..||:|.:|::....|...:|: :.:|:::|...|...|..::.||.|
Zfish   198 F-CFLFFIVGMGQISNYVAAFVLGMEILSSSVRDVYSTLGVCLFFSIGYMILPLAAFFLRDWRSL 261

  Fly   293 LRVLYAPAVLQILFLWILPESVRWLLSQGAEEKASNVLRRAARINQRPLPEEQLNDLLTSNRQKL 357
            :..|..|....|...|.:|||.|||||||..::|..::|:||:||:...|     |::.    .|
Zfish   262 MLALTIPGFFYIPLWWFIPESPRWLLSQGRVQEAEAIIRKAAKINRVTAP-----DVIF----PL 317

  Fly   358 SQANESQYPIMRAVVFFSLRIAN-------CCLCWFTHTLIALGLSLNSVNLGGNKYTNFMLNGF 415
            .|:.|....:....|...|:.:|       .||.|...::....||||:.:|.||.|.|.:|:..
Zfish   318 MQSTEDAGGVQSFSVCELLKSSNIRYMTGLLCLIWMAVSIGYCALSLNTSSLHGNIYLNCLLSAV 382

  Fly   416 IQIPGLLLPLVIMDRVGRRHSLCASMLLCAICMGASAAVPADNYAGSLALFLIGKLAITCSFQIL 480
            :::|.||:..:::....|||.|.:::.|..:.:.....:|.|..:.:|||.::||..::.:|.|:
Zfish   383 VEVPALLMAWLMLRLAPRRHCLASTLALGGLVLLLILLIPEDQSSVTLALVMLGKFGLSAAFSII 447

  Fly   481 YFFTSEIFPTNVRNTLLSLCSMVGRIGSMLAPQTPLLAKYYIYAPQILFATFALISGFLTLAFPE 545
            |..|:|::||.:|||.|..|||..|:|.:.||....|..|:...|.||.....::||.|:...||
Zfish   448 YPVTAELYPTVLRNTALGACSMSSRVGGISAPYFNYLGSYHRSLPYILIGGINVLSGLLSFLLPE 512

  Fly   546 TADKVLPTTIEEARDLNQAKRRS 568
            :....||.||.:.:.:...|:.|
Zfish   513 SRGSALPETIGQMQTVKGLKKHS 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7458	NP_649374.1	2A0119	46..554	CDD:273328	152/526 (29%)
		MFS	161..544	CDD:119392	119/391 (30%)
slc22a21	NP_001295487.1	2A0119	14..521	CDD:273328	152/526 (29%)
		MFS	146..511	CDD:119392	112/374 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	4.020