Protein Alignment CG7458 and Slc22a23

DIOPT Version :9

• Sequence 1: NP_649374.1
• Gene: CG7458 / 40441
• FlyBaseID: FBgn0037144
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: NP_001028339.1
• Gene: Slc22a23 / 73102
• MGIID: 1920352
• Length: 689
• Species: Mus musculus
• Alignment Length: 613
• Identity: 142/613 - (23%)
• Similarity: 234/613 - (38%)
• Gaps: 119/613 - (19%)

  Fly    20 HADAEAATQTAG---GDEDNSLDAILVRIGQFGRYQIINYVLLCVPMLFNAF--FSISYV----- 74
            |:...|||....   .|.|.|:...|..:|  |.||....||..:|.||..|  ||.|::
Mouse    63 HSSCCAATAAPSLLLLDYDGSVLPFLGGLG--GGYQKTLVVLTWIPALFIGFSQFSDSFLLDQPD 125

  Fly    75 -----------FTASTVVHRC-TVPQCDSPSSV--YEEDWLGFTIPKKNSAWD------------ 113
                       ...:||..|. .:....|||:.  ....| |.|..:.||: |
Mouse   126 FWCRGAGKGTELAGATVTGRWGDMGNWTSPSATPFSTASW-GTTSNRSNSS-DTPPLPSPPGKGN 188

  Fly   114 -----DCHRYAANISDAISGYTDPSGQYCLKEYFTITSETCGRDFKFRDEEKTISTEFGIYCEDE 173
                 |||.:...|...:.                                :.:.:::.:.|::.
Mouse   189 NDSNCDCHAWDYGIRTGLI--------------------------------QNVVSKWDLVCDNT 221

  Fly   174 WKLSMVGTINNVGQFVGIPLGGYFADRYGRRTMLAVAGSVSALMGVIRSLSSNYSMFLVFEFLDM 238
            ||:.:......||...|..:.|..||..|||.:|..:.....:.|:..:||.|.:||....|.:.
Mouse   222 WKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVLLFSTIFILIFGLTVALSVNVTMFSTLRFFEG 286

  Fly   239 AVGSTLFPTAFLLAIELVGPKRRVAAATIITIFYAL-GEAFLGFLASQVQHWRWLLRVLYAPAVL 302
            ...:.:..|.:.|.|||..|.:|. ..|::..|.|: |:..:..||:..:.|:.|..::..|.:|
Mouse   287 FCLAGIILTLYALRIELCPPGKRF-IITMVASFVAMAGQFLMPGLAALCRDWQVLQALIICPFLL 350

  Fly   303 QILFLWILPESVRWLLSQGAEEKASNVLRRAARINQRPLPEEQLNDLLTSNRQKLSQANESQYPI 367
            .:|:..|.|||:|||::....|.|..::....:.| ...||..:..::....::||: ...:..|
Mouse   351 MLLYWSIFPESLRWLMATQQFESAKKLILYLTQKN-CVSPESDIKGVMPELEKELSR-RPKKVCI 413

  Fly   368 MRAVVFFSL--RIANCCLCWFT----HTLIALGLSLNSVN--LGGNKYTNFMLNGFIQIPGLLLP 424
            ::.|...:|  .|...|:...|    |...|..:..:.|.  |..|.|.::.....|.:...|..
Mouse   414 VKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMGHEVKVPLLENFYADYYTMASIALASCLAM 478

  Fly   425 LVIMDRVGRRHSLCASMLLCA---------------------------ICMGASAAVPADNYAGS 462
            .:::..:|||..|...|:|.|                           :.:|.|.:| .|.:  |
Mouse   479 CLVVKFLGRRGGLLLFMILTALASLLQLGLLNLIGKYSQHPDSELQLKLAVGMSDSV-KDKF--S 540

  Fly   463 LALFLIGKLAITCSFQILYFFTSEIFPTNVRNTLLSLCSMVGRIGSMLAPQTPLLAKYYIYAPQI 527
            :|..::|..|......:..||.:||.||.:|...|.|.......|.:.||...|..:...:...|
Mouse   541 IAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQKGYFLHHI 605

  Fly   528 LFATFALISGFLTLAFPETADKVLPTTI 555
            :||...||.....|..||:.::.||..|
Mouse   606 IFACCTLICIICILLLPESRNQNLPENI 633

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7458	NP_649374.1	2A0119	46..554	CDD:273328	133/581 (23%)
		MFS	161..544	CDD:119392	100/418 (24%)
Slc22a23	NP_001028339.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..55
		2A0119	98..631	CDD:273328	128/572 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	162..188		6/27 (22%)
		MFS	230..>359	CDD:119392	36/129 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.100