DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7458 and slc22a13b

DIOPT Version :9

Sequence 1:	NP_649374.1	Gene:	CG7458 / 40441	FlyBaseID:	FBgn0037144	Length:	572	Species:	Drosophila melanogaster
Sequence 2:	XP_017209322.1	Gene:	slc22a13b / 556601	ZFINID:	ZDB-GENE-061013-532	Length:	549	Species:	Danio rerio

Alignment Length:	549	Identity:	166/549 - (30%)
Similarity:	258/549 - (46%)	Gaps:	71/549 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 ILVRIGQFGRYQIINYVLLCVPMLFNAFFSISYVFTASTVVHRCTVPQCDSPSSVYEEDWLGFTI 105
            ||..:|:||.:|....|.:|:|.:|.||.....||||.:..|.|
Zfish     7 ILSSVGEFGAFQKRLLVAVCLPNIFTAFHMFGQVFTAISFPHYC--------------------- 50

  Fly   106 PKKNSAWDDCHRYAANISDA----ISGYTDPSGQY--C------------LKEYFTITSETC--G 150
               ||:|  ..|.|.|:::.    ::...|..|||  |            ::.|...|:.:|  |
Zfish    51 ---NSSW--ILRQAPNLTEEKQLNLTVPLDSKGQYESCKMFTPVEMDIEDIEHYGINTTTSCIDG 110

  Fly   151 RDFKFRDEEKTISTEFGIYCEDEWKLSMVGTINNVGQFVGIPLGGYFADRYGRRTMLAVAGSVSA 215
            ..:|...:..|:.|||.:.||::.......:|...|..||..|.|..||:||||....::..:..
Zfish   111 WVYKAPKDSSTLITEFDLVCENKVYSEASQSIYMAGLLVGALLFGPMADKYGRRFATLLSLFLQF 175

  Fly   216 LMGVIRSLSSNYSMFLVFEFLDMAVGSTLFP---TAFLLAIELVGPKRRVAAATIITIFYALGEA 277
            |.||..:.|.|..:::...|:   ||:|:..   ..|:|..|..|..:|.....:...|:|:|..
Zfish   176 LSGVGVAFSPNIYVYIALRFV---VGTTISGISINTFVLGTEWCGSAKRALFTILSHCFFAIGLM 237

  Fly   278 FLGFLASQVQHWRWLLRVLYAPAVLQILFLWILPESVRWLLSQGAEEKASNVLRRAARINQRPLP 342
            .|..:|..:::||.|..||.||..|..::.||||||.||||:||..:.|...:.:|||||.|.:.
Zfish   238 LLSGVAYGIRNWRVLQLVLSAPVGLFFIYYWILPESARWLLTQGKLDSAKREILKAARINGRKVS 302

  Fly   343 EEQLNDLLTSNRQKLSQANESQYPIMRAVVFFSLRIANCCLCWFTHTLIALGLSLNSVNLGGNKY 407
            |..|:.:...|..|.|    :...:.| |.:...|....|..||..:|:..|:|||..|.|.:.|
Zfish   303 ENLLDKMEAENTAKSS----TMIDLFR-VGYLRKRALIMCYMWFVTSLVYYGVSLNVGNFGLDIY 362

  Fly   408 TNFMLNGFIQIPGLLLPLVIMDRVGRRHSLCASMLLCAICMGASA-----AVPADNYAGSLALFL 467
            ...::.|..:.|..|....::.|.|||  :|.|::|   .:|.:|     |:||........:.:
Zfish   363 LTQLIFGMAEFPARLSCFPLIQRFGRR--ICQSVVL---LLGGTACLIIPAIPAKYPIVVTVIAV 422

  Fly   468 IGKLAITCSFQILYFFTSEIFPTNVRNTLLSLCSMVGRIGSMLAPQTPLLAKYYIYAPQILFATF 532
            |||.::..||.|:|.:|:|::||.||...:.|.||..|:..:|||...||..|:...|.|::.:.
Zfish   423 IGKFSLAASFSIVYVYTAELYPTVVRQNGVGLNSMCARVAGILAPLIGLLDVYHHAIPMIIYGSL 487

  Fly   533 ALISGFLTLAFPETADKVLPTTIEEARDL 561
            ..:.|.||...|||    |.|.:::..|:
Zfish   488 PFVGGALTFLLPET----LNTDLQDHTDI 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7458	NP_649374.1	2A0119	46..554	CDD:273328	162/535 (30%)
CG7458	NP_649374.1	MFS	161..544	CDD:119392	126/390 (32%)
slc22a13b	XP_017209322.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	5.030