DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7458 and oatx

DIOPT Version :9

Sequence 1:	NP_649374.1	Gene:	CG7458 / 40441	FlyBaseID:	FBgn0037144	Length:	572	Species:	Drosophila melanogaster
Sequence 2:	XP_017208528.1	Gene:	oatx / 555218	ZFINID:	ZDB-GENE-070115-1	Length:	567	Species:	Danio rerio

Alignment Length:	541	Identity:	152/541 - (28%)
Similarity:	260/541 - (48%)	Gaps:	26/541 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 ILVRIGQFGRYQIINYVLLCVPMLFNAFFSISYVFTASTVVHRCTVPQCDSPSSVYEEDWLGFTI 105
            :|..:|.|||:|:|:..||.:|.|..|..::...|||....|.|.:|...:..:......|...|
Zfish     6 LLDEVGGFGRFQMIHVTLLSIPGLLMASQNLLNNFTAGVPEHHCRIPNVTTAMNDSTTTLLRAFI 70

  Fly   106 PKKNS-AWDDCHRYAAN----ISDAIS--GYTDPSGQYCLKEYFTITSETCGRDFKFRDEE--KT 161
            |..:| ....|.||...    |:|.:|  ..|:            :.:|.|...:.:...|  .:
Zfish    71 PLDSSLTLSKCSRYKDTQWHLITDKLSHGNATE------------LQTEGCADGWTYDKSEFISS 123

  Fly   162 ISTEFGIYCEDEWKLSMVGTINNVGQFVGIPLGGYFADRYGRRTMLAVAGSVSALMGVIRSLSSN 226
            |.:|:.:.|.......|..||...|...|..:.|..:||:||:.:|..:....||:|...:|:.:
Zfish   124 IVSEWDLVCTLRPLKQMSQTIYMGGVLTGAIIFGGLSDRFGRKALLIWSYFQLALLGSFTALAPS 188

  Fly   227 YSMFLVFEFL-DMAVGSTLFPTAFLLAIELVGPKRRVAAATIITIFYALGEAFLGFLASQVQHWR 290
            |.::.:|.|| .|:|...:. .|..|.:|.:..|.|....|:.:.|:..|:..|..:|..::.||
Zfish   189 YVVYCIFRFLTGMSVSGVIL-NAVSLKVEWIPTKTRTLVGTLSSFFFTFGQMVLAGVAYSLRDWR 252

  Fly   291 WLLRVLYAPAVLQILFLWILPESVRWLLSQGAEEKASNVLRRAARINQRPLPEEQLN-DLLTSNR 354
            .:...:..|..:..::.|...||.|||:..|..|:|..:|.|.|:||.:|...|::. :.|.|:.
Zfish   253 KIQMAVCLPFFIFFMYSWWFSESARWLVLNGRSEEALKLLHRVAKINGKPEMTEKITLEELESHM 317

  Fly   355 QKLSQANESQYPIMRAVVFFSLRIANCCL--CWFTHTLIALGLSLNSVNLGGNKYTNFMLNGFIQ 417
            ||..|:::|.|.:...:...::|..:.||  .||:.:....||:::....|.|.|...::.|.:.
Zfish   318 QKEVQSSKSIYTVFDLLRTPTMRKISMCLMVVWFSTSFAYYGLAMDLQKFGVNIYLMQVIFGAVD 382

  Fly   418 IPGLLLPLVIMDRVGRRHSLCASMLLCAICMGASAAVPADNYAGSLALFLIGKLAITCSFQILYF 482
            .|..|:.|:::..:|||.:..|.:|:.|..:.|:..||.|......||.::||...:.||..:|.
Zfish   383 FPAKLVALLMLSFLGRRLTQGACLLVSASIIFANIFVPEDMQVTRTALAVLGKGFTSASFTCVYL 447

  Fly   483 FTSEIFPTNVRNTLLSLCSMVGRIGSMLAPQTPLLAKYYIYAPQILFATFALISGFLTLAFPETA 547
            ||.|::||.:|.|.:...|.:.|||||.||...:|.......|.|::...|:|:|.:....|||.
Zfish   448 FTGELYPTVIRQTGMGFVSTMSRIGSMAAPAVLILDDILPALPSIVYGGSAVIAGLIAFLLPETL 512

  Fly   548 DKVLPTTIEEARDLNQAKRRS 568
            :..||.||::..:..:.|..:
Zfish   513 NIPLPDTIDDVEEKWEKKNNT 533

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7458	NP_649374.1	2A0119	46..554	CDD:273328	148/520 (28%)
CG7458	NP_649374.1	MFS	161..544	CDD:119392	112/386 (29%)
oatx	XP_017208528.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	6.030