DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7458 and Orct2

DIOPT Version :9

Sequence 1:	NP_649374.1	Gene:	CG7458 / 40441	FlyBaseID:	FBgn0037144	Length:	572	Species:	Drosophila melanogaster
Sequence 2:	NP_001262907.1	Gene:	Orct2 / 42890	FlyBaseID:	FBgn0086365	Length:	567	Species:	Drosophila melanogaster

Alignment Length:	591	Identity:	168/591 - (28%)
Similarity:	279/591 - (47%)	Gaps:	101/591 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 DAILVRIGQFGRYQIINYVLLCVPMLFNAFFSISYVFTASTVVHRCTVP-----QCDSPSSV--- 95
            |..::.:|.|||||.|.|.|:|:..:..||..::.||..:....||.:|     ..|.|:.:
  Fly     4 DEAIIHLGDFGRYQKIIYFLICLTSIPVAFHKLAGVFLLAKPDFRCALPFENGSSYDLPTHLWNL 68

  Fly    96 --------------YEEDWLGFTIPKKNSAWDDCHRYAANISDAISGYTDPSGQYCLKEYFTITS 146
                          |.|::|..:||:.::....|           |.|.....:| |....|..:
  Fly    69 SYPENERCSYYDVDYTEEYLNGSIPRSSNETKTC-----------SSYVYDRSKY-LNSAVTEWN 121

  Fly   147 ETCGRDFKFRDEEKTISTEFGIYCEDEWKLSMVGTINNVGQFVGIPLGGYFADRYGRRTMLAVAG 211
            ..|||||.....:               .|.|:|.:      :|..:.|..:|:|||:.:|..:.
  Fly   122 LVCGRDFMAATSD---------------SLFMLGVL------LGSIVFGQLSDKYGRKPILFASL 165

  Fly   212 SVSALMGVIRSLSSNYSMFLVFEFLDMAVGST---LFPTAFLLAIELVGPKRRVAAATIITIFYA 273
            .:..|.||:..::..|   ..:.|..:.||:|   :|..|:::|:|:|||.:|:.|...:.:|::
  Fly   166 VIQVLFGVLAGVAPEY---FTYTFARLMVGATTSGVFLVAYVVAMEMVGPDKRLYAGIFVMMFFS 227

  Fly   274 LGEAFLGFLASQVQHWRWLLRVLYAPAVLQILFLWILPESVRWLLSQGAEEKASNVLRRAARINQ 338
            :|.......|..|..||||...|..|.::.:.:.||:|||.||||.:|.::.|...:::|||.|:
  Fly   228 VGFMLTAVFAYFVHDWRWLQIALTLPGLIFMFYYWIIPESARWLLLKGRKDCAIANMQKAARFNK 292

  Fly   339 RPLPEEQLNDLL---TSNRQKLSQANESQ---------------YPIMR--AVVFFSLRIANCCL 383
            ..:.:|.|::||   .::.:|..|..|.|               ||.:|  .::.|        |
  Fly   293 VEISDEALSELLDEGENSEEKAKQKLEDQELDEGPPPSVWDLFCYPNLRRKTLLIF--------L 349

  Fly   384 CWFTHTLIALGLSLNSVNLGGNKYTNFMLNGFIQIPGLLLPLVIMDRVGRRHSLCASMLLCAICM 448
            .|...:.:..|||.|:.|||||...||:::|.::||..:..|:.::|.|||..||..:::..:.:
  Fly   350 DWLVTSGVYYGLSWNTSNLGGNVLLNFVISGAVEIPAYIFLLLTLNRWGRRSILCGCLVMAGLSL 414

  Fly   449 GASAAVPADNYAGSLALFLIGKLAITCSFQILYFFTSEIFPTNVRNTLLSLCSMVGRIGSMLAPQ 513
            .|:..:|...:...:|..::||||||.|:..:|.|::|.|||.|||..|...|||.||..|:||.
  Fly   415 LATVIIPQRMHTLIVACAMLGKLAITASYGTVYIFSAEQFPTVVRNVALGAASMVARISGMMAPF 479

  Fly   514 TPLLAKYYIYAPQILFATFALISGFLTLAFPETADKVLPTTIEEAR------------DLNQAKR 566
            ...||..:...|.::..:..|::|.|:|..|||.:|.:..||.:..            :..|..|
  Fly   480 LNFLATIWKPLPLLICGSLTLVAGLLSLLLPETHNKPMLETIADGERFGKKTKADVYLETGQELR 544

  Fly   567 RSERSP 572
            ..|..|
  Fly   545 APEAQP 550

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7458	NP_649374.1	2A0119	46..554	CDD:273328	161/552 (29%)
CG7458	NP_649374.1	MFS	161..544	CDD:119392	122/405 (30%)
Orct2	NP_001262907.1	2A0119	11..520	CDD:273328	161/552 (29%)
Orct2	NP_001262907.1	MFS	127..503	CDD:119392	121/407 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458336
Domainoid	1	1.000	100	1.000	Domainoid score	I351
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I321
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	7.000