Protein Alignment CG7458 and Slc22a14

DIOPT Version :9

• Sequence 1: NP_649374.1
• Gene: CG7458 / 40441
• FlyBaseID: FBgn0037144
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: NP_001032838.1
• Gene: Slc22a14 / 382113
• MGIID: 2685974
• Length: 629
• Species: Mus musculus
• Alignment Length: 578
• Identity: 139/578 - (24%)
• Similarity: 255/578 - (44%)
• Gaps: 92/578 - (15%)

  Fly    35 DNSLDAILVRIGQFGRYQIINYVLLCVPMLFNAFFSISYVF--TASTVVHRCTVPQCDSP----- 92
            |:...:::..||:||.:|....||..:|.:.:.||..|:.|  ||..       |.|::.
Mouse    48 DDKFASVMDAIGEFGTFQWRLVVLTFIPSILSTFFIFSHHFLLTAQR-------PYCNTSWILEV 105

  Fly    93 -SSVYEEDWLGFTIPK-KNSAWDDCHRYAANISDAIS------GYTDPSGQYCLKEYFTITSETC 149
             .::.|::.|..|:|: .|.::..|..|.....|..|      .||                |||
Mouse   106 GPNLTEDEQLNLTLPRAPNGSFLTCLMYIPVPWDLDSIIHFGLNYT----------------ETC 154

  Fly   150 --GRDFKFRDEEKTISTEFGIYCEDEWKLSMVGTINNVGQFVGIPLGGYFADRYGRRTMLAVAGS 212
              |..:.|. ..:::..||.:.|.:|.......|:...|...|..|.|:.:|:.||..::.::..
Mouse   155 KFGWIYPFA-HTRSLINEFDLVCGNEPNKENGLTVFLSGVLTGSLLFGFLSDKLGRYPIILLSLL 218

  Fly   213 VSALMGVIRSLSSNYSMFLVFEFL--DMAVGSTLFPTAFLLAIELVGPKRRVAAATIITIFYALG 275
            ...:.|...:..|::..:|.|.|.  ..:||..:...:  |.:|.:..:.|..|..:...|..:|
Mouse   219 GFLIFGFGTAFVSSFYQYLFFRFFVAQASVGYAICSVS--LVMEWLVGEHRAQAVILQHSFLTIG 281

  Fly   276 EAFLGFLASQVQHWRWLLRVLYAPAVLQILFLWILPESVRWLLSQGAEEKASNVLRRAARINQRP 340
            ...|..||.:|.|||.|..:...|....|..:|:|.||.|||:.:|..|:|..||..||.:|::.
Mouse   282 VILLTGLAYKVVHWRLLCLLGGMPMFPLICNIWVLRESPRWLMVRGKVEEAKKVLCYAAEVNKKT 346

  Fly   341 LPEEQLNDLLTSNRQKLSQA-------NESQYPIMRAVVFFSLRIANCCLCWFTHTLIALGLSLN 398
            :|...||:|..|.: |:::|       |:..:.::.|:        .|  .|||.:.|:..|:|.
Mouse   347 IPLNLLNELQISGK-KVAKASILDFCTNQHLFKVVLAI--------GC--VWFTVSYISFTLNLK 400

  Fly   399 SVNLGGNKYTNFMLNGFIQIPGLLLPLVIMDRVGRRHSLCASM-LLCAICMGASAAVPADNYAGS 462
            ..:.|.:.|...|:...:.:|..|..:::::..||:.:|..:: |:.::|: ....:|.:..:..
Mouse   401 MNDFGLDVYFVQMVRSIVAVPARLCCIILLEYFGRKWALNLTLFLVTSMCL-FLLFLPQEPKSTI 464

  Fly   463 LALFLIGKLAITCSFQILYFFTSEIFPTNVRNT---LLSLCSMVGRIGSM-----LAPQTPLLAK 519
            :...::.:.::..:..|.:.:|:|:.||.:|:|   ::||..:.|.|.|:     ...|.|:.
Mouse   465 ILTLMLAEFSMAGTLSIFFIYTAELLPTVLRSTGLGMVSLAWVAGAISSVAIFKQTKTQLPIF-- 527

  Fly   520 YYIYAPQILFATFALISGFLTLAF----PETADKVLPTTIE-EARDLNQAKRRSERSP 572
                        |..:...|.|.|    |||..:.|..:|| ..||..:.|.|::..|
Mouse   528 ------------FCCLCCVLALCFSSLVPETGSQSLRDSIEYNIRDSIEPKDRNKDVP 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7458	NP_649374.1	2A0119	46..554	CDD:273328	130/546 (24%)
		MFS	161..544	CDD:119392	95/404 (24%)
Slc22a14	NP_001032838.1	2A0119	59..553	CDD:273328	130/545 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167844040
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.040