DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7458 and CarT

DIOPT Version :9

Sequence 1:	NP_649374.1	Gene:	CG7458 / 40441	FlyBaseID:	FBgn0037144	Length:	572	Species:	Drosophila melanogaster
Sequence 2:	NP_610052.1	Gene:	CarT / 35334	FlyBaseID:	FBgn0032879	Length:	674	Species:	Drosophila melanogaster

Alignment Length:	565	Identity:	155/565 - (27%)
Similarity:	253/565 - (44%)	Gaps:	59/565 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 DEDNSLDAILVRIGQFGRYQIINYVLLCVPMLFN-AFFSISYVFTASTV-VHRCTVPQ-CDSPSS 94
            ||...||.:|..||:||:||.:....:|:|.... .|.:.:.:|.|.|. .:.|.:|: .|.|.
  Fly    31 DEAFDLDDLLPTIGEFGKYQKLLVFGICLPACIPCGFCAFNQLFMADTPDDYWCRIPELLDLPL- 94

  Fly    95 VYEEDWLGFTIPKK----NSAWDDCHRYAANISDAI-SGYTD------PSGQYCLKEYFTITSET 148
               |.....:|||:    ...:..|:.|..|.:..: ||..|      |:..:.|.:
  Fly    95 ---EQRKSLSIPKELDNDELVYSKCYTYGVNWTQLLESGEEDDLTTMEPNASWPLIK-------- 148

  Fly   149 CGRDFKFRDEE--KTISTEFGIYCEDEWKLSMVGTIN----NVGQFVGIPLGGYFADRYGRRTML 207
            |.:.:::....  .:|..:|.:.|:.:    :..||.    |.|..||:.|.|...||.|||...
  Fly   149 CPQGWEYNTSVVWSSIVIDFDLVCDQD----IYPTIGLAALNTGGPVGVYLFGLLNDRGGRRLSY 209

  Fly   208 AVAGSVSALMGVIRSLSSNYSMFLVFEFLDMAVGSTL---FPTAFLLAIELVGPKRRVAAATIIT 269
            .|..:......::.|||.:   |..:....:.||.|:   :...|::::||||...|.....:..
  Fly   210 FVCLATLLAGSLMTSLSKD---FWTWAGSRVIVGLTIPAVYQIPFIISLELVGENYRSFVTVMTC 271

  Fly   270 IFYALGEAFLGFLASQVQHWRWLLRVLYAPAVLQILFLWILPESVRWLLSQGAEEKASNVLRRAA 334
            .||..|...|..:....:.|..|..:...|.....|:::::|||.||||.:|..|:|..:|.|.|
  Fly   272 TFYTSGIMLLSGVTYLERDWVRLSYITSLPFYAYFLYMFVMPESPRWLLMRGRLEEALKILERMA 336

  Fly   335 RINQRPLPE--------EQLNDLLTSNRQKLSQ---ANESQYPIMRAVVFFSLRIANCCLCWFTH 388
            ::|.|..||        :...|.|...::|::.   |:..:.|.||      |:.....|.||.:
  Fly   337 KVNGREFPEAVHLKLEAQIRRDKLKKQKKKMANVGLADLCRTPNMR------LKTILITLSWFAN 395

  Fly   389 TLIALGLSLNSVNLGGNKYTNFMLNGFIQIPGLLLPLVIMDRVGRRHSLCASMLLCAICMGASAA 453
            ..:.||||.....||.|:|.:|.|:..:::|..|.....||..|||..|..||:|..:....:..
  Fly   396 ETVYLGLSYYGPALGTNQYVSFFLSAVVELPSYLCCWYFMDTWGRRWPLSLSMILGGVACVITVM 460

  Fly   454 VPADNYAGSLALFLIGKLAITCSFQILYFFTSEIFPTNVRNTLLSLCSMVGRIGSMLAPQTPLLA 518
            :|.|....:|.|:|:.|..::.||.|:|.|..|::||.||...:...|.:|.:|.:..|....|.
  Fly   461 LPDDAVDETLVLYLVSKALLSASFLIIYPFAGELYPTQVRGIGIGASSYIGGLGLIGIPFITYLG 525

  Fly   519 KYYIYAPQILFATFALISGFLTLAFPETADKVLPTTIEEARDLNQ 563
            |..:..|.::....:::.|...|..|||....||.||||..:..:
  Fly   526 KDNLKLPLVIMGFLSMLGGMTGLRLPETLHHRLPQTIEEGEEFGK 570

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7458	NP_649374.1	2A0119	46..554	CDD:273328	145/541 (27%)
CG7458	NP_649374.1	MFS	161..544	CDD:119392	112/400 (28%)
CarT	NP_610052.1	2A0119	44..561	CDD:273328	145/541 (27%)
CarT	NP_610052.1	MFS	182..551	CDD:119392	107/377 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	100	1.000	Domainoid score	I351
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I321
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	5.060