DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7458 and Slc22a13

DIOPT Version :9

Sequence 1:	NP_649374.1	Gene:	CG7458 / 40441	FlyBaseID:	FBgn0037144	Length:	572	Species:	Drosophila melanogaster
Sequence 2:	NP_001119757.1	Gene:	Slc22a13 / 316062	RGDID:	1306840	Length:	551	Species:	Rattus norvegicus

Alignment Length:	544	Identity:	142/544 - (26%)
Similarity:	247/544 - (45%)	Gaps:	51/544 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 ILVRIGQFGRYQIINYVLLCVPMLFNAFFSISYVFTASTVVHRCTVP-----------------Q 88
            ::..:|.|||:|:...:|:.:|...:|||..|.||......|.|:|.                 .
  Rat     7 VMAEVGDFGRFQVRLTILMGIPNFLSAFFVFSQVFMVLDEAHYCSVSWVKNHTFNLSAAEQLAVS 71

  Fly    89 CDSPSSVYEEDWLGFTIPKKNSAWDDCHRYAANISDAI-SGYTDPSGQYCLKEYFTITSETCGRD 152
            ..:.::...|..|.|..|..|::.:|...:..|.:.|. ||:..|
  Rat    72 IPNDTAGRPESCLMFRPPPDNASLEDILSHRFNETQACDSGWDYP-------------------- 116

  Fly   153 FKFRDEEKTISTEFGIYCEDEWKLSMVGTINNVGQFVGIPLGGYFADRYGRRTMLAVAGSVSALM 217
               .:...::..||.:.||.|.......::...|..||..:.|...|..|||..|.:...:|.:.
  Rat   117 ---ENRPPSLKNEFDLVCERENLKRTSQSVFMAGLLVGALVFGPVCDWIGRRPSLLMQLLLSGIA 178

  Fly   218 GVIRSLSSNYSMFLVFEFLDMAVGSTLFPTAFLLAIELVGPKRRVAAATIITIFYALGEAFLGFL 282
            .:..:..|::.:::...|......:....::.:|..|.||..||..|..:....:|||...|..|
  Rat   179 SMATAFVSSFELYMTLRFALATANAGFLLSSNVLLSEWVGTSRRTRAMVLAQSNFALGLMALAGL 243

  Fly   283 ASQVQHWRWLLRVLYAPAVLQILFLWILPESVRWLLSQGAEEKASNVLRRAARINQRPLPEEQLN 347
            |..|::||.|..:...|..|.:.:.|:||||.|||||||..|:|..::::||.:|.|||..|.||
  Rat   244 AYGVRNWRLLQIIGTTPIFLLVFYFWVLPESPRWLLSQGRTEEAKQLVQKAALVNGRPLASELLN 308

  Fly   348 DLLTSNRQKLSQANE-SQYPIMRAVVFFSLRIANCCLCWFTHTLIALGLSLNSVNLGGNKYTNFM 411
            .|:.........|.: .::|.:|.|....:.:      ||..:|:..||.....:.|.:.|...:
  Rat   309 QLVPEKTGPSGNALDLFRHPQLRKVTLILIAV------WFVDSLLYYGLGFQVGDFGLDIYLTQV 367

  Fly   412 LNGFIQIPGLLLPLVIMDRVGRRHSLCASMLLCAICMGASAAVPADNYAGSLALFLIGKLAITCS 476
            :.|.:::|..|..:.:|:::||:.|...::.|..:.......:|.|....:.||.::||.|.:.:
  Rat   368 IFGVVEVPARLSSIPMMEKLGRKWSQLCTLTLAGVMCVIIIFIPGDLPTVATALAVVGKFASSAA 432

  Fly   477 FQILYFFTSEIFPTNVRNTLLSLCSMVGRIGSMLAPQTPLLAKYYIYAPQILFATFALISGFLTL 541
            |.|.|.:|:|:.||.:|.|.:.|.|:..|:|.::.|...||.:|:...|.::|.:..:.:|.|..
  Rat   433 FTISYVYTAELLPTIIRQTGMGLVSIFSRVGGIITPLVMLLEQYHKAIPMLIFGSLPIGAGLLCA 497

  Fly   542 AFPETADKVLPTTIEEARDLNQAK 565
            ..|||..:.|..|::   ||.|.:
  Rat   498 LLPETRGQTLKDTLQ---DLEQGQ 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7458	NP_649374.1	2A0119	46..554	CDD:273328	138/526 (26%)
CG7458	NP_649374.1	MFS	161..544	CDD:119392	107/383 (28%)
Slc22a13	NP_001119757.1	2A0119	12..510	CDD:273328	138/526 (26%)
Slc22a13	NP_001119757.1	MFS	139..500	CDD:119392	102/366 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.030