Protein Alignment CG7458 and Slc22a21

DIOPT Version :10

• Sequence 1: NP_649374.1
• Gene: CG7458 / 40441
• FlyBaseID: FBgn0037144
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: XP_008765965.1
• Gene: Slc22a21 / 303140
• RGDID: 1561735
• Length: 555
• Species: Rattus norvegicus
• Alignment Length: 546
• Identity: 163/546 - (29%)
• Similarity: 275/546 - (50%)
• Gaps: 23/546 - (4%)

  Fly    39 DAILVRIGQFGRYQIINYVLLCVPMLFNAFFSISYVFTASTVVHRCTVPQCDSPSSVYEEDWL-- 101
            |.:...:|::|.:|.:.:.||...::.|.|..:|.||..::..|||.||...:.||.:....:
  Rat     5 DELTAFLGEWGPFQRLIFFLLSASIIPNGFTGLSAVFLTASPEHRCLVPDTVNLSSAWRNHSIPL 69

  Fly   102 ----GFTIPKKNSAWDDCHRY-AANISDAISGYTDPSGQYCLKEYFTITSETCGRDFKFRDEE-- 159
                |..:|.|      |.|| .|.|::..:...:|.....||:   :..|.|...:::..|.
  Rat    70 EMKDGRQVPHK------CRRYRLATIANFSALGLEPGEDVDLKQ---LELENCLDGWEYSKEVFL 125

  Fly   160 KTISTEFGIYCEDEWKLSMVGTINNVGQFVGIPLGGYFADRYGRRTMLAVAGSVSALMGVIRSLS 224
            .||.||:.:.|.|.||..:..::..||..:|..:.|..:||:||:.:|.....:......::..|
  Rat   126 STIVTEWNLVCNDAWKAPLTTSMFYVGVLLGSFISGQLSDRFGRKPVLFWTMGMHTGFSFLQVFS 190

  Fly   225 SNYSMF-LVFEFLDMAVGSTLFPTAFLLAIELVGPKRRVAAATI-ITIFYALGEAFLGFLASQVQ 287
            .|:.|| |:|..:.|...|. :..||:|..|::....|:..||: |.||:|.|...|...|..::
  Rat   191 VNFEMFTLLFALVGMGHISN-YVAAFVLGTEILSKSIRIIFATLGICIFFAFGFMVLPLFAYFIR 254

  Fly   288 HWRWLLRVLYAPAVLQILFLWILPESVRWLLSQGAEEKASNVLRRAARINQRPLPEEQLNDLLTS 352
            .||.||..:..|.||.....|.:|||.|||:|||..::|..::|:||:.|....|....:...|:
  Rat   255 DWRMLLMAITLPGVLCGALWWFIPESPRWLISQGRVKEAEVIIRKAAKFNGIVAPSTIFDPSETT 319

  Fly   353 NRQKLSQANESQYPIMRAVVFFSLRIAN--CCLCWFTHTLIALGLSLNSVNLGGNKYTNFMLNGF 415
            |.|..:..|...:.|...|...::||..  ..:.|.|.::...||||::.||.||.|.|..|...
  Rat   320 NLQDGNAKNTQSHHIYDLVRTRNIRILTIMSIILWLTISVGYFGLSLDTPNLNGNIYVNGFLLAA 384

  Fly   416 IQIPGLLLPLVIMDRVGRRHSLCASMLLCAICMGASAAVPADNYAGSLALFLIGKLAITCSFQIL 480
            :::|..:|..:::..|.||:|:..|:.|....:.....||:|....|.||.::||..||.::.::
  Rat   385 VEVPAYVLAWLLLQHVTRRYSMAGSLFLGGSVLLILQLVPSDLLYLSTALVMVGKFGITSAYSMV 449

  Fly   481 YFFTSEIFPTNVRNTLLSLCSMVGRIGSMLAPQTPLLAKYYIYAPQILFATFALISGFLTLAFPE 545
            |.:|:|::||.|||..:.:.|...|:||:|:|....|..|..:.|.|:..:..:::..:|..|||
  Rat   450 YVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRHLPYIVMGSLTILTAIITFFFPE 514

  Fly   546 TADKVLPTTIEEARDLNQAKRRSERS 571
            ::...||.||:|.:.:.:.:|.|..|
  Rat   515 SSGVSLPDTIDEMQKVKRIRRVSAMS 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7458	NP_649374.1	MFS_SLC22	150..544	CDD:340875	121/399 (30%)
Slc22a21	XP_008765965.1	2A0119	12..523	CDD:273328	156/520 (30%)