Protein Alignment CG7458 and Slc22a6

DIOPT Version :10

• Sequence 1: NP_649374.1
• Gene: CG7458 / 40441
• FlyBaseID: FBgn0037144
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: NP_058920.1
• Gene: Slc22a6 / 29509
• RGDID: 69338
• Length: 551
• Species: Rattus norvegicus
• Alignment Length: 540
• Identity: 139/540 - (25%)
• Similarity: 259/540 - (47%)
• Gaps: 24/540 - (4%)

  Fly    41 ILVRIGQFGRYQIINYVLLCVPMLFNAFFSISYVFTASTVVHRCTVPQCDSPSSVYEEDWLGFTI 105
            :|.::|..||:|:|...::..|:|..|..:....|||:...|.|..|   :.:::.::..|...:
  Rat     6 LLKQVGGVGRFQLIQVTMVVAPLLLMASHNTLQNFTAAIPPHHCRPP---ANANLSKDGGLEAWL 67

  Fly   106 P-KKNSAWDDCHRYAA-NISDAISGYTDPSGQYCLKEYFTITSETC--GRDFKFRDEEKTISTEF 166
            | .|....:.|.|:.: .........|:.:|        |..:|.|  |..:.......||.||:
  Rat    68 PLDKQGQPESCLRFTSPQWGPPFYNGTEANG--------TRVTEPCIDGWVYDNSTFPSTIVTEW 124

  Fly   167 GIYCEDEWKLSMVGTINNVGQFVGIPLGGYFADRYGRRTMLAVAGSVSALMGVIRSLSSNYSMFL 231
            .:.|.......:..::..||..:|..:.||.|||.|||.:|.:....:|:.|...:.:.||:::.
  Rat   125 NLVCSHRAFRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAAYAPNYTVYC 189

  Fly   232 VFEFLDMAVGSTLFPTAFLLAIELVGPKRRVAAATIITIFYALGEAFLGFLASQVQHWRWLLRVL 296
            ||..|.....:::......|.:|.:....|....|:|...|:||:..|..:|..|.|||.|..|:
  Rat   190 VFRLLSGMSLASIAINCMTLNVEWMPIHTRAYVGTLIGYVYSLGQFLLAGIAYAVPHWRHLQLVV 254

  Fly   297 YAPAVLQILFLWILPESVRWLLSQGAEEKASNVLRRAARINQRPLPEEQLN-DLLTSNRQK---L 357
            ..|..:..::.|...||.||..|.|..:.....|:|.||||.:.....:|: ::|.::.||   |
  Rat   255 SVPFFIAFIYSWFFIESARWYSSSGRLDLTLRALQRVARINGKQEEGAKLSIEVLRTSLQKELTL 319

  Fly   358 SQANESQYPIMRAVVFFSLRIANCCL--CWFTHTLIALGLSLNSVNLGGNKYTNFMLNGFIQIPG 420
            |:...|...::|..   :||....||  .||..:....||.::....|.:.|...::.|.:.:|.
  Rat   320 SKGQASAMELLRCP---TLRHLFLCLSMLWFATSFAYYGLVMDLQGFGVSMYLIQVIFGAVDLPA 381

  Fly   421 LLLPLVIMDRVGRRHSLCASMLLCAICMGASAAVPADNYAGSLALFLIGKLAITCSFQILYFFTS 485
            ..:..::::.:|||.:..||:||..||:..:..:|..:.....:|.::||..:..||..::.:|.
  Rat   382 KFVCFLVINSMGRRPAQMASLLLAGICILVNGIIPKSHTIIRTSLAVLGKGCLASSFNCIFLYTG 446

  Fly   486 EIFPTNVRNTLLSLCSMVGRIGSMLAPQTPLLAKYYIYAPQILFATFALISGFLTLAFPETADKV 550
            |::||.:|.|.|.:.|.:.|:||:::|...:.|::|...|..:|....:::..:|...|||..:.
  Rat   447 ELYPTVIRQTGLGMGSTMARVGSIVSPLVSMTAEFYPSMPLFIFGAVPVVASAVTALLPETLGQP 511

  Fly   551 LPTTIEEARDLNQAKRRSER 570
            ||.|:::.:..::.|:..::
  Rat   512 LPDTVQDLKSRSRGKQNQQQ 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7458	NP_649374.1	MFS_SLC22	150..544	CDD:340875	107/399 (27%)
Slc22a6	NP_058920.1	2A0119	11..515	CDD:273328	136/517 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	514..551		2/18 (11%)