Protein Alignment CG7458 and Slc22a12

DIOPT Version :9

• Sequence 1: NP_649374.1
• Gene: CG7458 / 40441
• FlyBaseID: FBgn0037144
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: NP_033229.3
• Gene: Slc22a12 / 20521
• MGIID: 1195269
• Length: 553
• Species: Mus musculus
• Alignment Length: 548
• Identity: 145/548 - (26%)
• Similarity: 249/548 - (45%)
• Gaps: 55/548 - (10%)

  Fly    41 ILVRIGQFGRYQIINYVLLCVPMLFNAFFSISYVFTASTVVHRCTVPQCDS-------PSSVYEE 98
            :|.|:|..||:|:...|.|..|:|:....::...|:|:...|||.||..|:       |..:..:
Mouse     6 LLDRVGGLGRFQLFQTVALVTPILWVTTQNMLENFSAAVPHHRCWVPLLDNSTSQASIPGDLGPD 70

  Fly    99 DWLGFTIPK------------KNSAWD--DCHRYAANISDAISGYTDPSGQYCLKEYFTITSETC 149
            ..|..:||.            :...|.  :.:..|.|.|||.   |:|.....:.::.|..|
Mouse    71 VLLAVSIPPGPDQQPHQCLRFRQPQWQLTESNATATNWSDAA---TEPCEDGWVYDHSTFRS--- 129

  Fly   150 GRDFKFRDEEKTISTEFGIYCEDEWKLSMVGTINNVGQFVGIPLGGYFADRYGRRTMLAVAGSVS 214
                       ||.|.:.:.|..:....|..:|...|..||..:.|:.:||:|||.:|..:..:.
Mouse   130 -----------TIVTTWDLVCNSQALRPMAQSIFLAGILVGAAVCGHASDRFGRRRVLTWSYLLV 183

  Fly   215 ALMGVIRSLSSNYSMFLVFEF-LDMAVGSTLFPTAFLLAIELVGPKRRVAAATIITIFYALGEAF 278
            ::.|...:....:.::.:|.| |..||...:..||.|| :|....:......|:..:.::.|:..
Mouse   184 SVSGTAAAFMPTFPLYCLFRFLLASAVAGVMMNTASLL-MEWTSAQGSPLVMTLNALGFSFGQVL 247

  Fly   279 LGFLASQVQHWRWLLRVLYAPAVLQILFLWILPESVRWLLSQGAEEKASNVLRRAARINQRPLPE 343
            .|.:|..|:.||.|...:.||..|..::.|.||||.|||::.|..::....|:|.|.:|:|....
Mouse   248 TGSVAYGVRSWRMLQLAVSAPFFLFFVYSWWLPESARWLITVGKLDQGLQELQRVAAVNRRKAEG 312

  Fly   344 EQLN-DLLTSNRQKLSQANES--------QYPIMRAVVFFSLRIANCCLCWFTHTLIALGLSLNS 399
            :.|. ::|.|..::....:::        ..|.:|.....|:      ||||.......||:|:.
Mouse   313 DTLTMEVLRSAMEEEPSRDKAGASLGTLLHTPGLRHRTIISM------LCWFAFGFTFYGLALDL 371

  Fly   400 VNLGGNKYTNFMLNGFIQIPGLLLPLVIMDRVGRRHSLCASMLLCAICMGASAAVPADNYAGSLA 464
            ..||.|.:....|.|.:..|.....|:::.|:|||....:.::|..:|:.::..||........|
Mouse   372 QALGSNIFLLQALIGIVDFPVKTGSLLLISRLGRRLCQVSFLVLPGLCILSNILVPHGMGVLRSA 436

  Fly   465 LFLIGKLAITCSFQILYFFTSEIFPTNVRNTLLSLCSMVGRIGSMLAPQTPLLAKYYIYAPQILF 529
            |.::|...:..:|..:..|:||:|||.:|.|.:.||.:..|.|:||.|...||..|..:.|.:::
Mouse   437 LAVLGLGCLGGAFTCITIFSSELFPTVIRMTAVGLCQVAARGGAMLGPLVRLLGVYGSWMPLLVY 501

  Fly   530 ATFALISGFLTLAFPETADKVLPTTIEE 557
            ....::||...|..|||.:..||.||::
Mouse   502 GVVPVLSGLAALLLPETKNLPLPDTIQD 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7458	NP_649374.1	2A0119	46..554	CDD:273328	141/538 (26%)
		MFS	161..544	CDD:119392	106/392 (27%)
Slc22a12	NP_033229.3	2A0119	11..526	CDD:273328	141/538 (26%)
		MFS	147..516	CDD:119392	102/375 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843318
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.960