Protein Alignment CG7458 and Slc22a1

DIOPT Version :9

• Sequence 1: NP_649374.1
• Gene: CG7458 / 40441
• FlyBaseID: FBgn0037144
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: NP_033228.2
• Gene: Slc22a1 / 20517
• MGIID: 108111
• Length: 556
• Species: Mus musculus
• Alignment Length: 554
• Identity: 153/554 - (27%)
• Similarity: 267/554 - (48%)
• Gaps: 33/554 - (5%)

  Fly    37 SLDAILVRIGQFGRYQIINYVLLCVPMLFNAFFSISYVFTASTVVHRCTVP-------QCD-SPS 93
            ::|.:|..:|:||.:|...::|||:.....|...:..||...|..|.|..|       :|. ||:
Mouse     3 TVDDVLEHVGEFGWFQKQAFLLLCLISASLAPIYVGIVFLGFTPDHHCRSPGVAELSQRCGWSPA 67

  Fly    94 SVYEEDWLGFTIPKKNSAWD-----DCHRYAANISDAISGYTDP-SGQYCLKEYFTITSETCGRD 152
               ||  |.:|:|...||.:     .|.:|..:.:.:.....|| |.....:.:..::  .|...
Mouse    68 ---EE--LNYTVPGLGSAGEASFLSQCMKYEVDWNQSTLDCVDPLSSLAANRSHLPLS--PCEHG 125

  Fly   153 FKFRDEEKTISTEFGIYCEDEWKLSMVGTINNVGQFVGIPLGGYFADRYGRRTMLAVAGSVSALM 217
            :.:.....:|.|||.:.|.|.||:.:..:..|:|.|:|..:.||.|||:||:..|.|...|::|.
Mouse   126 WVYDTPGSSIVTEFNLVCGDAWKVDLFQSCVNLGFFLGSLVVGYIADRFGRKLCLLVTTLVTSLS 190

  Fly   218 GVIRSLSSNYSMFLVFEFLDMAVGSTLFPTAFLLAIELVGPKRRVAAATIITIFYALGEAFLGFL 282
            ||:.:::.:|:..|:|..|...|....:.:.:.|..|.||...|...|.:..:.:.:|...|..:
Mouse   191 GVLTAVAPDYTSMLLFRLLQGMVSKGSWVSGYTLITEFVGSGYRRTTAILYQVAFTVGLVGLAGV 255

  Fly   283 ASQVQHWRWLLRVLYAPAVLQILFLWILPESVRWLLSQGAEEKASNVLRRAARINQRPLPEEQLN 347
            |..:..||||...:..|..|.:|:.|.:|||.||||||....:|..::.:.|:.| |.:|...|.
Mouse   256 AYAIPDWRWLQLAVSLPTFLFLLYYWFVPESPRWLLSQKRTTQAVRIMEQIAQKN-RKVPPADLK 319

  Fly   348 DLL----TSNRQKLSQANESQYPIMRAVVFFSLRIANCCLCWFTHTLIALGLSLNSVNLGGNKYT 408
            .:.    .|.|:..|.|:..:.|.:|......:.:      ||:..::..||.::....|.|.|.
Mouse   320 MMCLEEDASERRSPSFADLFRTPSLRKHTLILMYL------WFSCAVLYQGLIMHVGATGANLYL 378

  Fly   409 NFMLNGFIQIPGLLLPLVIMDRVGRRHSLCASMLLCAICMGASAAVPADNYAGSLALFLIGKLAI 473
            :|..:..::.|...:.||.:||:||.:.:.||.|:..........:|.:.:..::.|..:|::..
Mouse   379 DFFYSSLVEFPAAFIILVTIDRIGRIYPIAASNLVAGAACLLMIFIPHELHWLNVTLACLGRMGA 443

  Fly   474 TCSFQILYFFTSEIFPTNVRNTLLSLCSMVGRIGSMLAP-QTPLLAKYYIYAPQILFATFALISG 537
            |...|::....:|::||.:||..:.:||.:..:|.:..| ....|.:.:...|.|||....|.:|
Mouse   444 TIVLQMVCLVNAELYPTFIRNLGMMVCSALCDLGGIFTPFMVFRLMEVWQALPLILFGVLGLSAG 508

  Fly   538 FLTLAFPETADKVLPTTIEEARDLNQAKRRSERS 571
            .:||..|||....||.|||||.:|.:.|.:::.:
Mouse   509 AVTLLLPETKGVALPETIEEAENLGRRKSKAKEN 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7458	NP_649374.1	2A0119	46..554	CDD:273328	144/526 (27%)
		MFS	161..544	CDD:119392	109/387 (28%)
Slc22a1	NP_033228.2	2A0119	12..525	CDD:273328	144/526 (27%)
		MFS	125..515	CDD:119392	109/396 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843893
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.960