Protein Alignment CG7458 and Y66D12A.13

DIOPT Version :10

• Sequence 1: NP_649374.1
• Gene: CG7458 / 40441
• FlyBaseID: FBgn0037144
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: NP_499489.1
• Gene: Y66D12A.13 / 190497
• WormBaseID: WBGene00013439
• Length: 533
• Species: Caenorhabditis elegans
• Alignment Length: 595
• Identity: 128/595 - (21%)
• Similarity: 229/595 - (38%)
• Gaps: 136/595 - (22%)

  Fly    33 DEDNSLDAILVRIGQFGRYQIINYVLLCVPMLFNAFFSISYVFTASTVVHRCTVPQCDSPSSVYE 97
            |:...|||..:.:..|..:.|..       ||.|..|:   :|.|:..    .:|.||.
 Worm     7 DDIFELDAYQLVVLAFNEFLIFT-------MLSNVVFN---MFGAAAP----RLPGCDD------ 51

  Fly    98 EDWLGFTIPKKNSAWDDCHRYAANISDAISGYTDPSGQYCLKEYFTITSETCGR--DFKFRDEEK 160
                  .|....|.:..|.:|.|::.     ..:|:.:|..|.......|.|.|  :..:.|
 Worm    52 ------IIYNATSPFQQCEQYDAHLD-----CEEPAMEYEFKSVAVEFQELCSRHNEHSYMD--- 102

  Fly   161 TISTEFGIYCEDEWKLSMVGTINN------VGQFVGIPLG----GYFADRYGRRTMLAVAGSVSA 215
            :|:..||              :||      ..|.:||.||    |..:|.|||:.:..:...:..
 Worm   103 SITQLFG--------------VNNRVRFSTTSQMIGIMLGSAIAGQLSDLYGRKKITLLFLCMML 153

  Fly   216 LMGVIRSLSSNYSMFLVFEFLDMAVGSTLFPTAFLLAIELVGPKRRVAAATIITIFYALGEAFLG 280
            ......|.||:..:|::..|........|.....:|.:|.:....|:..:|::|  :|.......
 Worm   154 FFSTSSSFSSSIEVFIIVRFFIGICCGGLTTVGSILVVENLPSAHRLWMSTVVT--WAPNYMLFA 216

  Fly   281 FLASQVQHWRWLLRVLYAPAVLQILF-LWILPESVRWLLSQGAEE---KASNVLRRAARINQRPL 341
            ..|.....||.|.|:..|..|:.||. .::||||.::|:.....:   |:...:.:..|:..: |
 Worm   217 LFAYITGEWRCLARMCNAMTVIAILICAFLLPESPKYLIQARKGKLAVKSIKYINKFKRVRNQ-L 280

  Fly   342 PEEQLNDLLTS--NRQKLSQANESQYPIMRAVVF--FSLRIANCCLCWFTHTLIALGLSLNSVNL 402
            .:.::.|::.|  .....|:|...:|..:...:.  .:::.....:..|:.:.:..||..|...|
 Worm   281 TDTEIEDVVHSAIEVDTKSRAKAKKYSFIHLYIHPKITVQTVVASISMFSVSYVTYGLLFNYDVL 345

  Fly   403 GGNKYTNFMLNGFIQ-IPGLLLPLVIMDRVG-------RRHSLCASMLLCAICMGA-------SA 452
            .|:.|.|..::||:: :.|.:  :.::|..|       |.|.:..|.::|  ||..       ..
 Worm   346 TGSIYMNAAVSGFLRYVVGAV--VAVLDHFGGEHVGRKRMHFITVSFIMC--CMFGIFFIYFNDL 406

  Fly   453 AVPADNYAGSLALFLIGKLAITCSFQILYFFTSEIFPTNVRNTLLSLCSMVGRIGSMLAPQTPLL 517
            .:...::..:|.|...|...  |.|..|...|:|:|||.:||...:..::.||:|::..|.
 Worm   407 VLEYKSWIRALTLLAFGTTG--CLFLQLLLITAEMFPTGIRNIASAHINVCGRLGNVFGPM---- 465

  Fly   518 AKYYIYAPQILFATFALISGFLTLA-------------FPETADKVLP----------------- 552
                :::.::.||.    ||:|.|.             .|||.::.||
 Worm   466 ----VFSYKLGFAG----SGYLILGVICLLDVIVFHIFIPETKNQPLPQGMPSRKKQRKDPEVQK 522

  Fly   553 --TTIEEARD 560
              |||.|..|
 Worm   523 SLTTISEEPD 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7458	NP_649374.1	MFS_SLC22	150..544	CDD:340875	93/441 (21%)
Y66D12A.13	NP_499489.1	2A0119	36..506	CDD:273328	113/531 (21%)