Protein Alignment CG7458 and T12B3.2

DIOPT Version :10

• Sequence 1: NP_649374.1
• Gene: CG7458 / 40441
• FlyBaseID: FBgn0037144
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: NP_501177.1
• Gene: T12B3.2 / 188439
• WormBaseID: WBGene00020445
• Length: 478
• Species: Caenorhabditis elegans
• Alignment Length: 555
• Identity: 112/555 - (20%)
• Similarity: 203/555 - (36%)
• Gaps: 172/555 - (30%)

  Fly    54 INYVLLC--VPMLFNAFFSISYVFTASTVVHRCTVPQCDSPSSVYEED---W-LGFTIPKKNSAW 112
            ||...:|  :...|..||:...:|                  .:|..:   | .|.:.|.|
 Worm     5 INRFHICAFITWQFANFFAGQNIF------------------GIYSNNVSKWKCGDSKPTK---- 47

  Fly   113 DDCHRY----AANISDAISGYTDPSGQYCLKEYFTITSETCGRDFKFRDEEKTISTEFGIYCEDE 173
             ||:.|    .:|::     :.||..|....|:..|    ||....::
 Worm    48 -DCNIYLSCPKSNLT-----FVDPPFQSAAIEFDWI----CGSSVFYQ----------------- 85

  Fly   174 WKLSMVGTINNVGQFVGIPLGGYFADRYGRRTMLAVAGSVSALMGVIRSLSSNYSMFLVFEFLDM 238
               |....:..||..:|..|.|..:||:|||.:        .::.:..::.|.::..|....
 Worm    86 ---SFFSQVQYVGVLIGTLLFGSLSDRFGRRPI--------GILVISNAICSTFASGLAPSV--- 136

  Fly   239 AVGSTLFPTAFLLAI--------------ELVGPKRRVAAATIITIFYALG--EAFLGFLASQVQ 287
               ..|||..||:.:              |::.|::|:    ::..|:..|  ..||..:....:
 Worm   137 ---KILFPLRFLVGLSIGGMLVVICAWIMEVILPQQRM----VVRGFFNWGWTRIFLTSICYFTR 194

  Fly   288 HWR---WLLRVLYAPAVLQILFLWILPESVRWLLSQGAEEKASNVLRRAARINQRPL-------- 341
            .||   ::..:...||:|.::|  ::|||..||.|:|.:.:......:.|||...|.
 Worm   195 EWRLATYVSSLSLIPALLLVIF--VIPESPVWLHSRGFKARMIQSEMQIARIAGVPYVPVQHKLV 257

  Fly   342 -PEEQLNDLLTSNRQKLSQANESQYPIMRAVVFFSLRIANCCLCWFTHTLIALGLSLNSVNLGGN 405
             |:..::.|.|....|            :..:.:::        ||...:......|:|..|.|:
 Worm   258 RPKSLMDTLKTKGMFK------------KLFILWTM--------WFIIAICGFANDLSSGTLAGD 302

  Fly   406 KYTNFMLNGFIQIPGLLLPLVIMD---------------RVGRRHSLCASMLLCAICMGASAAVP 455
            .|.|.:..|.:.:...:| |:.:|               ::|   :||..::|       :..:.
 Worm   303 LYLNQLFFGILLVFSKML-LLFVDTYFTNFKRRTLHQGSQIG---TLCCFIIL-------TTFMS 356

  Fly   456 ADNYA-GSLALFLIGKLAITCSFQILYFFTSEIFPTNVRNTLLSLCSMVGRIGSMLAPQTPLLAK 519
            .|.:. |.|.::|||...|..::...|....|:..|..|.:....||::.|||.:|||
 Worm   357 MDYHGIGVLIVYLIGTTFIEYTWDACYLCAIELMETPSRASATGSCSLIARIGMILAP------- 414

  Fly   520 YYIYA-----PQILFATFALISGFLTLAF---PET 546
            :..||     |.:......|.|..|.:::   ||:
 Worm   415 FLTYANTWWSPAVNVTVIVLGSANLLISYFFLPES 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7458	NP_649374.1	MFS_SLC22	150..544	CDD:340875	88/445 (20%)
T12B3.2	NP_501177.1	2A0119	<64..456	CDD:273328	96/468 (21%)