DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7458 and K09C4.4

DIOPT Version :9

Sequence 1:	NP_649374.1	Gene:	CG7458 / 40441	FlyBaseID:	FBgn0037144	Length:	572	Species:	Drosophila melanogaster
Sequence 2:	NP_001361998.1	Gene:	K09C4.4 / 187194	WormBaseID:	WBGene00019549	Length:	524	Species:	Caenorhabditis elegans

Alignment Length:	489	Identity:	109/489 - (22%)
Similarity:	198/489 - (40%)	Gaps:	80/489 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   138 LKEYFTITSETCGRDFKFRDEEKTISTEFGIYCEDEWKLSMVGTINNVGQFVGIPLGGYF----A 198
            |.:.|.|.::|. .|.    ...|:.|.:|| ......:|::.::....:.||..|...|    |
Worm    26 LTQTFPILADTI-NDM----NNHTLMTHYGI-TPTVTSISIMNSMITSSETVGTLLSLIFLIPMA 84

  Fly   199 DRYGRRTMLAVAGS----VSALMGVIRSLSSNYSMFL---VFEFLDMAVGSTLFPTAFLLAIELV 256
            |..||:.::....|    :|||..|:.:.|.:...|:   :||.|...:|:  |.||..:| |..
Worm    85 DTKGRKFLVIYMRSALLILSALCQVLSAYSQSAEFFIMSKLFEGLQHPLGT--FLTALFIA-ECA 146

  Fly   257 GPKRRVAAATIITIFYALGEAFLGFLASQVQHWR---WLLRVLYAPAVLQILFLWI--LPESVRW 316
            ..|.|..|.|.:.:...:....:..:||.....:   |.:..|.|.....::.:|:  ||||.:|
Worm   147 PDKNRGFACTSLVVLVGIVRMIMLPIASPAVLGKADTWFVFPLAALISSFLVLIWVCRLPESPKW 211

  Fly   317 LLSQGAEEKASNVLRRAARINQRPLPEEQLNDLLTSNRQKLSQANESQ---------------YP 366
            |:.|...|:|    :|:..........|..|::|.|..::.:...||.               :.
Worm   212 LVCQNRIEEA----KRSIEYYHGNDSSENFNNVLLSIVKEKNLTIESHISLREVLQNDTLREGFK 272

  Fly   367 IMRAVVFFSLRIANCCLCWFTHTL-IALGLSL-NSVNLGGNKYTNFMLNGFIQIPGLLLPLVIMD 429
            ::.:.:||.|..::..|..:|..| .:.|.:. .::|:.       ::...:..|...:..:::|
Worm   273 VLFSFLFFILIDSDNALSVYTVLLHKSAGFTTQEAININ-------LIISIVFFPTQFIGTLLID 330

  Fly   430 RVGRRHSLCAS--MLLCAICMGASAAVPADNYAGSLALFLIGKLAITC-----------SFQILY 481
            .:|||.:.|..  |:....|:...... |..:.|:..:..|..:.|.|           |.:||
Worm   331 YLGRRPAFCIGGFMIFIKSCLLLLVQF-AIYFFGANLITKIIDIIIACLGSGPNATGMSSLRIL- 393

  Fly   482 FFTSEIFPTNVRNTLLSLCSMVG-RIGSMLAPQTPLLAKYY---IYAPQILFATFALISGFLTLA 542
             |.:|:||.:.|.::..:..... .|.|.|....|||..::   .:.|.:....|..|  :|...
Worm   394 -FITELFPPSARTSISQIMLFTSLAINSSLLSSFPLLYSWFPPAFFTPLVFTQMFFGI--YLYRY 455

  Fly   543 FPETADKVLPTTIEEARDLNQAKRR----SERSP 572
            .|||..:.: ..|.|:.|...|.|.    .|::|
Worm   456 MPETKGRAV-CDIIESFDEEVASRSVSFLQEKTP 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7458	NP_649374.1	2A0119	46..554	CDD:273328	102/465 (22%)
CG7458	NP_649374.1	MFS	161..544	CDD:119392	94/432 (22%)
K09C4.4	NP_001361998.1	MFS	42..462	CDD:391944	97/439 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910