Protein Alignment CG7458 and F45E10.2

DIOPT Version :10

• Sequence 1: NP_649374.1
• Gene: CG7458 / 40441
• FlyBaseID: FBgn0037144
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: NP_001022174.1
• Gene: F45E10.2 / 185801
• WormBaseID: WBGene00009729
• Length: 538
• Species: Caenorhabditis elegans
• Alignment Length: 550
• Identity: 134/550 - (24%)
• Similarity: 239/550 - (43%)
• Gaps: 115/550 - (20%)

  Fly    38 LDAILVRIGQFGRYQIINYVLLCVPMLFNAFFSISYVFTASTVVHRCTVPQCDSPSSVYEEDWLG 102
            |::|...:|.|||:|.|.::|:|:|:.|.:...:|:.|..|.....|.
 Worm    68 LESIFEGLGSFGRFQQIQFILICIPIAFVSMHVMSWTFVVSPARKICN----------------- 115

  Fly   103 FTIPKKNSAWDDCHRYAANISD--AISGYTDPSGQYCLKEYFTITSETCGRDFKFRDEEKTISTE 165
               ....:..|.|...|.:.||  .:.|
 Worm   116 ---ETNETRIDGCEELAYSASDRWEMDG------------------------------------- 140

  Fly   166 FGIYCEDEWKLSMVGTINNVGQFVGIPLGGYFADRYGRRTML---AVAGSVSALMGVIRSLSSNY 227
                 ::.|..:.|..:..:||.:|....|..||:.||:.:|   .|...|.||:.::.
 Worm   141 -----DNGWIRATVQAVYFIGQMIGSFTCGVMADKIGRKKVLFWCLVLQVVCALLLIVA------ 194

  Fly   228 SMFLVFEFLDMAVGST---LFPTAFLLAIELVGPKRRVAAATIITIFYALGEAFLGFLASQVQHW 289
            ..:.::..|....|.|   ::..|.:|.|||||.|.|...|.|..:|..:|...|..:|..:..:
 Worm   195 PTWWIYAILKAGTGFTQPGIYGVAVVLGIELVGKKYRSFIAVIANVFGVIGGVLLAVMAYFIVDY 259

  Fly   290 RWLLRVLYAPAVLQILFLWILPESVRWLLSQGAEEKASNVLRRAARINQRPLP-------EEQLN 347
            |.|...:..|:::.|.:.|::.||.|||:||...:.|:.||...|..|::.:|       |::::
 Worm   260 RLLHASIAIPSLIFITYYWMIHESARWLVSQEKYDDANVVLCATANWNKKTIPKNWAEKIEKKMD 324

  Fly   348 DLLTSNRQKLSQANESQYPIMRAVVFFSLRIANCCLCWFTHTLIALGLSLNSVNLGGNKYTNFML 412
            ...|..:......:..:.|.||     ...|||..: |...|::..||::.|...||:.:..|:.
 Worm   325 VTATKKKDSFGVFDLIRTPQMR-----KRTIANFVM-WPVTTMMYYGLTMRSDVGGGSLFVTFVT 383

  Fly   413 NGFIQIPGLLLPLVIMDRVGRR--HS---LCASMLLCAICMGASAAVPADNYAGSLALFLIGKLA 472
            :..:::|.:::..:::||:|||  :|   ..|.|||.|..: ....:|: .||  :.:.::.|.|
 Worm   384 SQLMELPAVIIVALLIDRLGRRIMYSGAIFTAGMLLLASWL-THDLIPS-QYA--VIMLMVAKGA 444

  Fly   473 ITCSFQILYFFTSEIFPTNVRNTLLSLCSMVGRIGSMLAPQTPLLAKYYIYAPQILFATFALISG 537
            ::.::.::|.:|||:|||.:|||.:..||.:.|.|::.|   ..:|.:.:..    |....:|..
 Worm   445 VSVAYTVMYTYTSELFPTVIRNTAVGCCSTIARFGAISA---SFIAFFLVDR----FGRIVMIIP 502

  Fly   538 FLTLA----------FPETADKVLPTTIEE 557
            |..||          .|||.::.||.:|.|
 Worm   503 FTILALCASIVSWTMLPETVNQQLPDSISE 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7458	NP_649374.1	MFS_SLC22	150..544	CDD:340875	105/421 (25%)
F45E10.2	NP_001022174.1	MFS_SLC22	121..518	CDD:340875	111/461 (24%)