Protein Alignment CG7458 and hmit-1.2

DIOPT Version :9

• Sequence 1: NP_649374.1
• Gene: CG7458 / 40441
• FlyBaseID: FBgn0037144
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: NP_507624.1
• Gene: hmit-1.2 / 180206
• WormBaseID: WBGene00013074
• Length: 613
• Species: Caenorhabditis elegans
• Alignment Length: 547
• Identity: 103/547 - (18%)
• Similarity: 186/547 - (34%)
• Gaps: 186/547 - (34%)

  Fly   174 WKLSMVGTINNVGQFVGIPLGGYFADRYGRR------TMLAVAGSVSALMGVIRSLSSNYSMFLV 232
            ||..:|.....:.. ||....|..:|||||:      |::.|.|:|...:...:.:     |.:.
 Worm    67 WKEVIVSITPGMAA-VGAWFSGAGSDRYGRKPIIIGSTLIFVCGAVICAVAWTKIV-----MLIG 125

  Fly   233 FEFLDMAVGSTLFPTAFLLAIELVGPKRRVAAATIITIF---YALGEAFLGFLASQVQHWR---- 290
            ..||.:.:|.    .:.::.:.|..........|:::.|   .:.|:.....:.....:|.
 Worm   126 RIFLGVGIGF----ASMVVPVYLGEASPTHVRGTLVSAFAMMISFGQVVANIMGGVFSYWEPYTI 186

  Fly   291 -WLLRVLYA--PAVLQILFLWILPESVRWLLSQGAEEKASNVLRRAARINQRPLPEEQLNDLLT- 351
             |.|...:|  ||::|.:....|||:.|||...|..|:|..||.:....|...: |.:|.::.|
 Worm   187 GWRLMFAFAGIPALIQFVCFIFLPETPRWLYENGHTEQAEQVLEKIYGGNTEWI-EYELAEIKTY 250

  Fly   352 -SNRQKLSQANESQYPIMRAVV-----------------FFSLRIANCCLCWFT----------- 387
             ..|||..:..:...|::..::                 |..|...|..| ::|
 Worm   251 AEERQKQMEEEKKSGPVIWRILKTPHVLKACFIGSMLQAFQQLAGINTIL-YYTADIIRSAGIEN 314

  Fly   388 -HTLIALGLSLNSVNLGGNKYTNFMLNGFIQIPGLLLPLVIMDRVGRRHSL---CASMLLCAICM 448
             ||:|.:.:.|:..||                .|...|:..::::|||...   ||.:::..:.:
 Worm   315 YHTIIWISVILSICNL----------------IGPFAPMFFIEKLGRRKLFLFSCAGVVVSLVLI 363

  Fly   449 GA---------------SAAVPADNYAGS------------------------------------ 462
            |.               ||.:.|.||..:
 Worm   364 GVSFLLVGNDSAPNFDRSAYLLAGNYQSNGEAESCLMLSNCDSCVTSEHCGFCEDSETRTGFCLP 428

  Fly   463 ---------------------------------------------LALFLIG--KLAITCSFQIL 480
                                                         |.:.::|  .|..:|.|..|
 Worm   429 VDHNDVTLYSSTGLCTNGLDKSNSSFPNATSYVWQKHHCTTSYTILPIVMMGVYLLTFSCGFTSL 493

  Fly   481 -YFFTSEIFPTNVRNTLLSLCSMVGRIGSMLAPQTPLLAKYYI--YAPQILFATFALISGFLTLA 542
             :...||.:|...|:|.:|:.::...:.:::...|.|...:.|  |....|:|.|.:|: |:.:.
 Worm   494 PWVLNSEFYPMWARSTCVSISTLSNWVFNLIIALTYLSLTHAITKYGAFWLYAIFTIIA-FIFIY 557

  Fly   543 F--PETADKVLPTTIEEARDLNQAKRR 567
            |  |||..    .:|:|...|...||:
 Worm   558 FLVPETTG----YSIDEVEMLFMNKRQ 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7458	NP_649374.1	2A0119	46..554	CDD:273328	98/532 (18%)
		MFS	161..544	CDD:119392	95/522 (18%)
hmit-1.2	NP_507624.1	MFS	32..562	CDD:421695	95/523 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910