Protein Alignment CG7458 and hmit-1.1

DIOPT Version :9

• Sequence 1: NP_649374.1
• Gene: CG7458 / 40441
• FlyBaseID: FBgn0037144
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: NP_507623.1
• Gene: hmit-1.1 / 180205
• WormBaseID: WBGene00013073
• Length: 606
• Species: Caenorhabditis elegans
• Alignment Length: 519
• Identity: 99/519 - (19%)
• Similarity: 191/519 - (36%)
• Gaps: 156/519 - (30%)

  Fly   189 VGIPLGGYFADRYGRRTMLAVAGSVSALMGVIRSLSSNYSMFLVFE-FLDMAVG-STLFPTAFLL 251
            ||..:.|..:|..|||.::..|.::..:..::.:.|.|..|.||.. .|.:|:| :::....:|.
 Worm    80 VGSLMSGTSSDYIGRRKVILGASAIFTIGALVCAASVNKIMLLVGRVLLGIAIGFASMIVPVYLG 144

  Fly   252 AIELVGPKRRVAAATIITIFYA------LGEAFLGFLASQVQHWRWLLRVLYAPAVLQILFLWIL 310
            .......:..:.||..:.|.:.      .|.|| .::......||.:......|:::|.:....|
 Worm   145 ETAPTHVRGMLVAAFALMISFGQVVANITGGAF-SYIDPYNVGWRLMFAFAAVPSIIQFVCFMFL 208

  Fly   311 PESVRWLLSQGAEEKASNVLRRAARINQRPLPEEQLNDLLTSNRQKLSQANESQY---PIMRAVV 372
            ||:.|||...|.|.:...||.:... ..:...|.::.:::..|..: ::.||..:   |::..::
 Worm   209 PETPRWLYENGFETETREVLEKVYN-GDKEWVEYEMAEIIAFNEDQ-AKENEKAHASGPVIWRIL 271

  Fly   373 -----------------FFSLRIANCCLCWFTHTLIALGLSLNSVNLGGNKYTNFMLN--GFIQI 418
                             |..|...|..|.:....:.:.|:|.|...:    :.:.:|:  .||
 Worm   272 KTPHVLKACFIGSMLQAFQQLAGINTILYYTADIIRSSGISNNHTTI----WISVLLSLCNFI-- 330

  Fly   419 PGLLLPLVIMDRVGRRHSL---CASMLLCAICMG---------ASAAVPADNYA----------- 460
             |..:|:.::::||||...   |..::|..:.:|         ::|.:||:.|.
 Worm   331 -GPFVPMSLIEKVGRRIIFLFSCGLVVLSLVFIGVAFLLVNHDSAATLPANQYGSNFNSSYPDAK 394

  Fly   461 GSLAL----FLI---------------------------------------GKLA---------- 472
            |.:|.    :.:                                       |.:|
 Worm   395 GCMAYSNCDYCVTTDACGFCHDANTKQGYCLPAGFDNPEVYSSTGSCTNSNGSIANNFKWEKYYC 459

  Fly   473 ---------ITCSFQILYF---FT-------SEIFPTNVRNTLLSLCSMVGRIGSMLAPQTPLLA 518
                     |.|...:|.|   ||       ||.:|...|:|.:::.:....:.::      ::|
 Worm   460 DTKYTLLPIIACGVYLLTFSSGFTSLPWVLNSEFYPMWARSTCVAISTTSNWVFNL------IIA 518

  Fly   519 KYYIYAPQIL--FATFALISGFLTLAF-------PETADKVLPTTIEEARDL--NQAKRRSERS 571
            ..|:...|::  :..|.|.:|...:||       |||..    .:|||...|  |:.:||...|
 Worm   519 LTYLSLTQVIGKYGAFWLYAGLTVIAFIFILFLVPETKG----YSIEEVEMLFMNKKQRREAES 578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7458	NP_649374.1	2A0119	46..554	CDD:273328	91/498 (18%)
		MFS	161..544	CDD:119392	88/488 (18%)
hmit-1.1	NP_507623.1	MFS_HMIT_like	31..554	CDD:340918	88/489 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910