DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7458 and Ust5r

DIOPT Version :9

Sequence 1:	NP_649374.1	Gene:	CG7458 / 40441	FlyBaseID:	FBgn0037144	Length:	572	Species:	Drosophila melanogaster
Sequence 2:	NP_599207.2	Gene:	Ust5r / 171398	RGDID:	620985	Length:	552	Species:	Rattus norvegicus

Alignment Length:	573	Identity:	146/573 - (25%)
Similarity:	236/573 - (41%)	Gaps:	74/573 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 ILVRIGQFGRYQIINYVLLCVPMLFNAFFSISYV-------FTASTVVHRCTVP------QCDSP 92
            :|.::|..||:||:.       |.|....::|.|       |||:...|||.||      ..|:.
  Rat     6 LLNQVGSLGRFQILQ-------MAFVFLINVSVVPHSTIENFTAAIPSHRCWVPILDNVTVSDNH 63

  Fly    93 SSVYEED-WLGFTIP-KKNSAWDDCHRYA------ANISDAISGYTDPSGQYCLKEYFTITSETC 149
            |.:..:| .|..:|| ..:...|.|.|:|      .:::|..|..|:...:.|:.
  Rat    64 SRILNQDKLLKISIPLDSHLRLDKCRRFAQPQWHLLDLNDTFSSVTEADTEPCVD---------- 118

  Fly   150 GRDFKFRDEEKTISTEFGIYCEDEWKLSMVGTINNVGQFVGIPLGGYFADRYGRRTMLAVAGSVS 214
            |..:...:...|..||:.:.||.:...|:......:|.|:|..:.|..:||:||:.:|..|....
  Rat   119 GWVYDRSNFHSTTVTEWDLVCESQVLNSVTKFSFMIGAFIGGIVNGPLSDRFGRKFVLKCALLQM 183

  Fly   215 ALMGVIRSLSSNYSMFLVFEFLDMAVGSTLFP---TAFLLAIELVGPKRRVAAATIITIFYALGE 276
            |:.......:||:.::....||   .|.|..|   .:.||..|....|.....:.|.....:.|.
  Rat   184 AITETCVGFASNFFIYCSLRFL---AGMTFEPILVNSNLLMFEWTSHKFLAMMSVIAPCAGSFGS 245

  Fly   277 AFLGFLASQVQHWRWLLRVLYAPAVLQILFLWILPESVRWLLSQGAEEKASNVLRRAARINQRPL 341
            ..|..||.|.|:|..|...:..|....::....|.||.|||:.....:|....||:.|.:|....
  Rat   246 MILAGLAFQFQNWHHLQLAMSVPIFFFLILTRWLSESARWLIVTNKPQKGLKELRKVAHMNGMKN 310

  Fly   342 PEEQL--NDLLTSNRQKLSQANES-------QYPIMRAVVFFSLRIANCCLCWFTHTLIAL---G 394
            ..:.|  ..:.||.:::|..|...       ..||:|..:         |...|...|..|   |
  Rat   311 SGDNLTMEVVRTSMKRELEAAKARPSPRDLFHTPILRKRI---------CAMSFMRILFMLSIFG 366

  Fly   395 LSLNSVNLGGNKYTNFMLNGFIQIPGLLLPLVI----MDRVGRRHSLCASMLLCAICMGASAAVP 455
            :||:..:|.    :|.||..|:.....||..||    .:|:|||.:....|.|..||:..:..||
  Rat   367 MSLHLQHLS----SNIMLLQFVVSASSLLFSVIGPYVFNRMGRRITQMVVMTLRGICILTAVFVP 427

  Fly   456 ADNYAGSLALFLIGKLAITCSFQILYFFTSEIFPTNVRNTLLSLCSMVGRIGSMLAPQTPLLAKY 520
            .:.....:.:..:.......||.:....|:|:.||.:|.|.:.:..|.|..|..|||...:||.|
  Rat   428 QEMQILRITVVTLAGAFSALSFGVNRLHTNELLPTTLRATAIGVIGMFGNSGFFLAPLFMILASY 492

  Fly   521 YIYAPQILFATFALISGFLTLAFPETADKVLPTTIEE-ARDLNQAKRRSERSP 572
            ....|.|.:..|::::||.....|||.::.||..|.: ..|..::::..:..|
  Rat   493 SPNLPWIFYGGFSILNGFTVFLLPETKNQPLPDCIHDIGNDWEESRQEMKEDP 545

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7458	NP_649374.1	2A0119	46..554	CDD:273328	142/547 (26%)
CG7458	NP_649374.1	MFS	161..544	CDD:119392	105/401 (26%)
Ust5r	NP_599207.2	MFS_OAT	109..516	CDD:340932	108/432 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347317
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.940